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Endocrine Regulatory Mechanisms of Blood Flow: Vasoactive Peptides

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PanVascular Medicine

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Abstract

Several vasoactive substances released from the peripheral or autonomic nervous system, the adrenals, and the kidneys support the regulation of vascular tone and cardiac output through endocrine, autocrine, and paracrine mechanisms. Dysregulation of the expression or activation of renin-angiotensin-aldosterone system (RAS), kallikrein-kinin system (KKS), and the catecholamine or vasoactive peptide signaling pathways can affect cardiac homeostasis and might thus be targets for therapeutic interventions in the treatment of several diseases.

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Abbreviations

Desensitization:

Diminished response of the receptor due to prolonged stimulation. It is considered to be protective against overstimulation.

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Authors and Affiliations

  1. Endocrinology and Nutrition Department, Complejo Hospitalario Universitario Insular Materno-Infantil de Gran Canaria, Av Marítima del sur s/n, Las Palmas de Gran Canaria, 35016, Spain

    Julia Charlotte Wiebe Ph.D. & Ana María Wägner M.D., Ph.D.

Authors
  1. Julia Charlotte Wiebe Ph.D.
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  2. Ana María Wägner M.D., Ph.D.
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Corresponding author

Correspondence to Julia Charlotte Wiebe Ph.D. .

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Editors and Affiliations

  1. Akademisches Lehrkrankenhaus MLU, Bitterfeld-Wolfen, Germany

    Peter Lanzer

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Wiebe, J.C., Wägner, A.M. (2013). Endocrine Regulatory Mechanisms of Blood Flow: Vasoactive Peptides. In: Lanzer, P. (eds) PanVascular Medicine. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-37393-0_168-1

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  • DOI: https://doi.org/10.1007/978-3-642-37393-0_168-1

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  • Publisher Name: Springer, Berlin, Heidelberg

  • Online ISBN: 978-3-642-37393-0

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