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Elastic, Viscoelastic, and Fracture Properties of Bone Tissue Measured by Nanoindentation

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Handbook of Nanomaterials Properties

Abstract

Nanoindentation is a sophisticated technique that has been used to characterize a wide selection of materials, including bone. Given the complex and hierarchical nature of bone, nanoindentation allows for assessment of composite material properties at the nano-range of bone tissue. These nanoindentation-based measures can provide important baseline information to aid in understanding the overall mechanical behavior, the pathologic changes of disease, and the pharmaceutical response of bone. In this review, the challenges and limitations of our current knowledge related to nanoindentation are presented as well as the future directions for its application to bone biology.

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Authors and Affiliations

  1. Division of Orthodontics, College of Dentistry, The Ohio State University, 4088 Postle Hall, 305W. 12th Ave, 43210-1267, Columbus, OH, USA

    Do-Gyoon Kim & Kathy L. Elias

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  1. Do-Gyoon Kim
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  2. Kathy L. Elias
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Correspondence to Do-Gyoon Kim .

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Editors and Affiliations

  1. Nanoprobe Laboratory for Bio- & Nanotechnology and Biomimetics, Ohio State University, Columbus, Ohio, USA

    Bharat Bhushan

  2. Department of Biological and Environmental Engineering, Cornell University, Ithaca, New York, USA

    Dan Luo

  3. Division of Restorative, Prosthetic and Primary Care, The Ohio State University, College of Dentistry, Columbus, Ohio, USA

    Scott R. Schricker

  4. Department of Materials Science and Engineering, University of Florida, Gainesville, Florida, USA

    Wolfgang Sigmund

  5. Department of Mechanical Engineering and Materials Science, Duke University, Durham, North Carolina, USA

    Stefan Zauscher

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Kim, DG., Elias, K.L. (2014). Elastic, Viscoelastic, and Fracture Properties of Bone Tissue Measured by Nanoindentation. In: Bhushan, B., Luo, D., Schricker, S., Sigmund, W., Zauscher, S. (eds) Handbook of Nanomaterials Properties. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-31107-9_46

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