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Esophageal Motility

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Esophageal and Gastric Disorders in Infancy and Childhood

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Abstract

Esophageal motility testing evaluates the two most important physiologic functions of the esophagus: to provide appropriate muscle response, including two functional sphincters coordinated with the contraction of muscle from esophageal body, and to conduct food bolus from the pharynx into the stomach. Tests used to access esophageal contraction include stationary and prolonged esophageal manometry and, most recently, high-resolution manometry (HRM). Tests to evaluate bolus transmission include videocineroentgenography, esophageal transit scintigraphy, esophageal impedance monitoring, and, recently, esophageal motility testing, which consists and concomitant monitoring of the pressure profile and the impedance tracings.

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References

  1. Skandalakis JE, Ellis H. Embryologic and anatomic basis of esophageal surgery. Surg Clin North Am. 2000;80(1):85–155.

    Google Scholar 

  2. Kahrilas PJ, Dodds WJ, Dent J, Logemann JA, Shaker R. Upper esophageal sphincter function during deglutition. Gastroenterology. 1988;95(1):52–62.

    Google Scholar 

  3. Sivarao DV, Goyal RK. Functional anatomy and physiology of the upper esophageal sphincter. Am J Med. 2000;108(Suppl 4a):27S–37.

    Article  PubMed  Google Scholar 

  4. Mu L, Sanders I. The innervation of the human upper esophageal sphincter. Dysphagia. 1996;11(4):234–8.

    Article  CAS  PubMed  Google Scholar 

  5. Jadcherla SR, Shaker R. Esophageal and upper esophageal sphincter motor function in babies. Am J Med. 2001;111(Suppl 8A):64S–8.

    Google Scholar 

  6. Pandolfino JE, Ghosh SK, Zhang Q, Han A, Kahrilas PJ. Upper sphincter function during transient lower oesophageal sphincter relaxation (tlosr); it is mainly about the microburps. Neurogastroenterol Motil. 2007;19:203–10.

    Article  CAS  PubMed  Google Scholar 

  7. Jadcherla SR, Gupta A, Stoner E, Fernandez S, Shaker R. Pharyngeal swallowing: defining pharyngeal and upper esophageal sphincter relationships in human neonates. J Pediatr. 2007;151(6):597–603.

    Google Scholar 

  8. Kuo B, Urma D. Esophagus – anatomy and development. Goyal & Shaker. 2006. http://www.nature.com/gimo/contents/pt1/full/gimo6.html. Accessed 11 Aug 2010.

  9. Lynn RB. Mechanisms of esophageal pain. Am J Med. 1992;92(5A):11S–9.

    Article  CAS  PubMed  Google Scholar 

  10. Aziz Q, Thompson DG. Brain-gut axis in health and disease. Gastroenterology. 1998;114(3):559–78.

    Google Scholar 

  11. Holloway RH. Esophageal body motor response to reflux events: secondary peristalsis. Am J Med. 2000;108(Suppl 4a):20S–6.

    Article  PubMed  Google Scholar 

  12. Miller MJ, Kiatchoosakun P. Relationship between respiratory control and feeding in the developing infant. Semin Neonatol. 2004;9(3):221–7.

    Google Scholar 

  13. Goyal RK, Chaudhury A. Physiology of normal esophageal motility. J Clin Gastroenterol. 2008;42(5):610–9.

    Google Scholar 

  14. Diamant NE. Neuromuscular mechanisms of primary peristalsis. Am J Med. 1997;103(5A):40S–3.

    Article  CAS  PubMed  Google Scholar 

  15. Yamato S, Spechler SJ, Goyal RK. Role of nitric oxide in esophageal peristalsis in the opossum. Gastroenterology. 1992;103(1):197–204.

    Google Scholar 

  16. Gidda JS, Goyal RK. Influence of successive vagal stimulations on contractions in esophageal smooth muscle of opossum. J Clin Invest. 1983;71(5):1095–103.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  17. Staiano A, Boccia G, Salvia G, Zappulli D, Clouse RE. Development of esophageal peristalsis in preterm and term neonates. Gastroenterology. 2007;132(5):1718–25.

    Google Scholar 

  18. Gupta A, Gulati P, Kim W, Fernandez S, Shaker R, Jadcherla SR. Effect of postnatal maturation on the mechanisms of esophageal propulsion in preterm human neonates: primary and secondary peristalsis. Am J Gastroenterol. 2009;104(2):411–9.

    Google Scholar 

  19. Shaker R, Lang IM. Effect of aging on the deglutitive oral, pharyngeal, and esophageal motor function. Dysphagia. 1994;9(4):221–8.

    Article  CAS  PubMed  Google Scholar 

  20. Eckardt VF, LeCompte PM. Esophageal ganglia and smooth muscle in the elderly. Am J Dig Dis. 1978;23(5):443–8.

    Article  CAS  PubMed  Google Scholar 

  21. Jadcherla SR, Hoffmann RG, Shaker R. Effect of maturation of the magnitude of mechanosensitive and chemosensitive reflexes in the premature human esophagus. J Pediatr. 2006;149(1):77–82.

    Google Scholar 

  22. Apaydin N, Uz A, Elhan A, Loukas M, Tubbs RS. Does an anatomical sphincter exist in the distal esophagus? Surg Radiol Anat. 2008;30(1):11–6.

    Google Scholar 

  23. Mittal RK, Balaban DH. The esophagogastric junction. N Engl J Med. 1997;336(13):924–32.

    Google Scholar 

  24. Goyal RK, Rattan S. Genesis of basal sphincter pressure: effect of tetrodotoxin on lower esophageal sphincter pressure in opossum in vivo. Gastroenterology. 1976;71(1):62–7.

    Google Scholar 

  25. Mittal RK, Rochester DF, McCallum RW. Electrical and mechanical activity in the human lower esophageal sphincter during diaphragmatic contraction. J Clin Invest. 1988;81(4):1182–9.

    Google Scholar 

  26. Newell SJ, Sarkar PK, Durbin GM, Booth IW, McNeish AS. Maturation of the lower oesophageal sphincter in the preterm baby. Gut. 1988;29(2):167–72.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  27. Yeo C, Dempsey D, Klein AS, Pemberton JH, Peters JH. Shackelford’s surgery of the alimentary tract. 6th ed. Philadelphia: Saunders; 2006.

    Google Scholar 

  28. Kuribayashi S, Massey BT, Hafeezullah M, Perera L, Hussaini SQ, Tatro L, Darling RJ, Franco R, Shaker R. Terminating motor events for tlesr are influenced by the presence and distribution of refluxate. Am J Physiol Gastrointest Liver Physiol. 2009;297(1):G71–5.

    Google Scholar 

  29. Boulant J, Mathieu S, D’Amato M, Abergel A, Dapoigny M, Bommelaer G. Cholecystokinin in transient lower oesophageal sphincter relaxation due to gastric distension in humans. Gut. 1997;40(5):575–81.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  30. Passaretti S, Zaninotto G, Martino ND, Leo P, Costantini M, Baldi F. Standards for oseophageal manometry. A position statement from the gruppo italinao di studio motilita apparato digerente (gismad). Dig Liver Dis. 2000;32(1):46–56.

    Article  CAS  PubMed  Google Scholar 

  31. Tutuian R, Mainie I, Agrawal A, Gideon RM, Katz PO, Castell DO. Symptom and function heterogenicity among patients with distal esophageal spasm: studies using combined impedance-manometry. Am J Gastroenterol. 2006;101:464–9.

    Article  PubMed  Google Scholar 

  32. Katz P, Menin R, Gideon R. Utility and standards in esophageal manometry. J Clin Gastroenterol. 2008;42(5):620–6.

    Article  PubMed  Google Scholar 

  33. Chitkara DK, Fortunato C, Nurko S. Prolonged monitoring of esophageal motor function in healthy children. J Pediatr Gastroenterol Nutr. 2004;38(2):192–7.

    Article  PubMed  Google Scholar 

  34. Hussain S, Lorenzo CD. Motility disorders. Diagnosis and treatment for the pediatric patient. Pediatr Clin North Am. 2002;49(1):27–51.

    Article  PubMed  Google Scholar 

  35. Pandolfino JE, Fox MR, Bredenoord AJ, Kahrilas PJ. High-resolution manometry in clinical practice: utilizing pressure topography to classify oesophageal motility abnormalities. Neurogastroenterol Motil. 2009;21(8):796–806.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  36. Gideon R. Manometry: technical issues. Gastrointest Endoscopic Clin N Am. 2005;15(2):243–55.

    Article  Google Scholar 

  37. Pandolfino JE, Bulsiewicz WJ. Evaluation of esophageal motor disorders in the era of high-resolution manometry and intraluminal impedance. Curr Gastroenterol Rep. 2009;11:182–9.

    Article  PubMed  Google Scholar 

  38. Pursnani K, Oeffner C, Gideon R, Castell D. Comparison of lower oesophageal sphincter pressure measurement using circumferential vs unidirectional transducers. Neurogastroenterol Motil. 1997;9(3):177–80.

    Article  CAS  PubMed  Google Scholar 

  39. Jee S-R, Pimentel M, Soffer E, Conklin JL. A high-resolution view of achalasia. J Clin Gastroenterol. 2009;43(7):644–51.

    Article  PubMed  Google Scholar 

  40. Kahrilas PJ, Ghosh SK, Pandolfino JE. Esophageal motility disorders in terms of pressure topography: the Chicago classification. J Clin Gastroenterol. 2008;42(5):627–35.

    Article  PubMed  PubMed Central  Google Scholar 

  41. Panebianco V, Tomei E, Anzidei M, Habib FI, Catalano C, Lisi D, Laghi A, Passariello R. Functional mri in the evaluation of oesophageal motility: feasibility, mri patterns of normality, and preliminary experience in subjects with motility disorders. Gastrointest Radiol. 2006;11:881–9.

    Google Scholar 

  42. Bremner RM, Costantini M, DeMeester TR, Bremner CG, Hoeft SF, Crookes PF, Peters JH, Hagen JA. Normal esophageal body function: a study using ambulatory esophageal manometry. Am J Gastroenterol. 1998;93:183–7.

    Article  CAS  PubMed  Google Scholar 

  43. vanHerwaarden MA, Katz PO, Gideon RM, Barrett J, Castell JA, Achem S, Castell DO. Are manometric parameters of the upper esophagus sphincter and pharynx affected by age and gender? Dysphagia. 2003;18:211–7.

    Article  Google Scholar 

  44. Fox MR, Bredenoord AJ. Oesophageal high-resolution manometry: moving from research into clinical practice. Gut. 2008;57:405–23.

    Article  CAS  PubMed  Google Scholar 

  45. Kahrilas PJ, Sifrim D. High-resolution manometry and impedance-ph/manometry: valuable tools in clinical and investigational esophagology. Gastroenterology. 2008;135(3):756–69.

    Article  PubMed  PubMed Central  Google Scholar 

  46. Goldani HAS, Staiano A, Borrelli O, Thapar N, Lindley KJ. Pediatric esophageal high-resolution manometry: utility of a standardized protocol and size-adjusted pressure topography parameters. Pediatrics. 2010;105:460–7.

    Google Scholar 

  47. Russo S, LoRe G, Galia M, Reginelli A, LoGreco V, D’Agostino T, Tona GL, Coppolina F, Grassi R, Midiri M, Lagalia R. Videofluorograpphy swallow study of patients with systemic sclerosis. Gastrointest Radiol. 2009;114:948–59.

    CAS  Google Scholar 

  48. Fordham LA. Imaging of the esophagus in children. Radiol Clin North Am. 2005;43(2):283–302.

    Article  PubMed  Google Scholar 

  49. Levine MS, Rubesin SE, Laufer I. Barium esophagography: a study for all seasons. Clin Gastroenterol Hepatol. 2008;6(1):11–25.

    Google Scholar 

  50. Summerton SL. Radiographic evaluation of esophageal function. Gastrointest Endoscopic Clin N Am. 2005;15(2):231–42.

    Article  Google Scholar 

  51. Andersson M, Kostic S, Ruth M, Lonroth H, Kjellin A, Hellstrom M, Lundell L. Characteristics of timed barium esophagogram in newly diagnosed idiopathic achalasia: clinical and manometric correlates. ACTA Radiol. 2007;48:2–9.

    Article  CAS  PubMed  Google Scholar 

  52. Schima W, Stacher G, Pokieser P, Uranitsch K, Nekahm D, Schober E, Moser G, Tscholakoff D. Esophageal motor disorders: videofluoroscopic and manometric evaluation – prospective study in 88 symptomatic patients. Radiology. 1992;185:487–91.

    Article  CAS  PubMed  Google Scholar 

  53. Mariani G, Boni G, Barreca M, Bellini M, Fattori B, AlSharif A, Grosso M, Stasi C, Costa F, Anselmino M, Marchi S, Rubello D, Strauss HW. Radionuclide gastroesophageal motor studies. J Nucl Med. 2004;45(6):1004–28.

    PubMed  Google Scholar 

  54. Iascone C, Di Giulio E, Maffi C, Ruperto M. Use of radioisotopic esophageal transit in the assessment of patients with symptoms of reflux and non-specific esophageal motor disorders. Dis Esophagus. 2004;17(3):218–22.

    Google Scholar 

  55. Klein HA. Esophageal transit scintigraphy. Semin Nucl Med. 1995;25(4):306–17.

    Article  CAS  PubMed  Google Scholar 

  56. Chung JJ, Park HJ, Yu JS, Hong YJ, Kim JH, Kim MJ, Lee SI. A comparison of esophagography and esophageal transit scintigraphy in the evaluation of usefulness of endoscopic pneumatic dilatation in achalasia. Acta Radiol. 2008;49(5):498–505.

    Google Scholar 

  57. Blonski W, Hila A, Vela MF, Castell DO. An analysis of distal esophageal impedance in individuals with and without esophageal motility abnormalities. J Clin Gastroenterol. 2008;42(7):776–81.

    Google Scholar 

  58. Imam H, Shay S, Ali A, Baker M. Bolus transit patterns in healthy subjects: a study using simultaneous impedance monitoring, videoesophagram, and esophageal manometry. Am J Physiol Gastrointest Liver Physiol. 2005;288(5):G1000–6.

    Google Scholar 

  59. Szczesniak MM, Rommel N, Dinning PG, Fuentealba SE, Cook IJ, Omari TI. Optimal criteria for detecting bolus passage across the pharyngo-oesophageal segment during the normal swallow using intraluminal impedance recording. Neurogastroenterol Motil. 2008;20(5):440–7.

    Google Scholar 

  60. Tutuian R, Castell DO. Esophageal function testing: role of combined multichannel intraluminal impedance and manometry. Gastrointest Endosc Clin N Am. 2005;15(2):265–75.

    Google Scholar 

  61. Sperandio M, Tutuian R, Gideon RM, Katz PO, Castell DO. Diffuse esophageal spasm: not diffuse but distal esophageal spasm (des). Dig Dis Sci. 2003;48(7):1380–4.

    Article  PubMed  Google Scholar 

  62. Bredenoord AJ, Smout AJ. Esophageal motility testing: impedance-based transit measurement and high-resolution manometry. Gastroenterol Clin North Am. 2008;37(4):775–91.

    Google Scholar 

  63. Madarena E, Bonanno E, Skaggs B, Woodley F, H HM. Impedance is an effective method for characterizing bolus transit and clearance in children. J Pediatr Gastroenterol Nutr. 2009;49(S1):E83.

    Google Scholar 

  64. Bredenoord AJ, Tutuian R, Smout AJ, Castell DO. Technology review: esophageal impedance monitoring. Am J Gastroenterol. 2007;102(1):187–94.

    Article  PubMed  Google Scholar 

  65. Conchillo JM, Selimah M, Bredenoord AJ, Samsom M, Smout AJPM. Assessment of oesophageal emptying in achalasia patients by intraluminal impedance monitoring. Neurogastroenterol Motil. 2006;18:971–7.

    Article  CAS  PubMed  Google Scholar 

  66. Bredenoord AJ, Weusten BL, Sifrim D, Timmer R, Smout AJ. Aerophagia, gastric, and supragastric belching: a study using intraluminal electrical impedance monitoring. Gut. 2004;53(11):1561–5.

    Google Scholar 

  67. Savarino E, Tutuian R. Combined multichannel intraluminal impedance and manometry testing. Dig Liver Dis. 2008;40(3):167–73.

    Google Scholar 

  68. Bulsiewicz WJ, Kahrilas PJ, Kwiatek MA, Ghosh SK, Meek A, Pandolfino JE. Esophageal pressure topography criteria indicative of incomplete bolus clearance: a study using high-resolution impedance manometry. Am J Gastroenterol. 2009;104(11):2721–8.

    Google Scholar 

  69. Nguyen HN, Domingues GR, Lammert F. Technological insights: combined impedance manometry for esophageal motility testing-current results and further implications. World J Gastroenterol. 2006;12(39):6266–73.

    Article  PubMed  PubMed Central  Google Scholar 

  70. Yigit T, Quiroga E, Oelschlager B. Multichannel intraluminal impedance for the assessment of post-fundoplication dysphagia. Dis Esophagus. 2006;19(5):382–8.

    Google Scholar 

  71. Montenovo M, Tatum RP, Figueredo E, Martin AV, Vu H, Quiroga E, Pellegrini CA, Oelschlager BK. Does combined multichannel intraluminal esophageal impedance and manometry predict postoperative dysphagia after laparoscopic nissen fundoplication? Dis Esophagus. 2009;22(8):656–63.

    Google Scholar 

  72. Tutuian R, Vela MF, Balaji NS, Wise JL, Murray JA, Peters JH, Shay SS, Castell DO. Esophageal function testing with combined multichannel intraluminal impedance and manometry: multicenter study in healthy volunteers. Clin Gastroenterol Hepatol. 2003;1(3):174–82.

    Google Scholar 

  73. Cho YK, Choi MG, Park JM, Oh JH, Paik CN, Lee JW, Lee IS, Kim SW, Chung IS. Evaluation of esophageal function in patients with esophageal motor abnormalities using multichannel intraluminal impedance esophageal manometry. World J Gastroenterol. 2006;12(39):6349–54.

    Article  PubMed  PubMed Central  Google Scholar 

  74. Lacy BE, Weiser K. Esophageal motility disorders: medical therapy. J Clin Gastroenterol. 2008;42(5):652–8.

    Article  PubMed  Google Scholar 

  75. Korakaki E, Hatzidaki E, Manoura A, Velegrakis G, Charissis G, Gourgiotis D, Giannakopoulou C. Feeding difficulties in a neonate with primary cricopharyngeal achalasia treated by cricopharyngeal myotomy. Int J Pediatr Otorhinolaryngol. 2004;68:249–53.

    Article  PubMed  Google Scholar 

  76. Erdeve O, Kologlu M, Saygili B, Atasay B, Arsan S. Primary cricopharyngeal achalasia in a newborn treated by balloon dilatation: a case report and review of the literature. Int J Pediatr Otorhinolaryngol. 2007;71:165–8.

    Article  PubMed  Google Scholar 

  77. DeCaluwe D, Nassogne MC, Reding R, deVilledeGoyet J, Clapuyt P, Otte JB. Cricopharyngeal achalasia: case reports and review of the literature. Eur J Pediatr Surg. 1999;9:109–12.

    Article  CAS  Google Scholar 

  78. Munoz AA, Shapiro J, Cuddy LD, Misono S, Bhattacharyya N. Videofluoroscopic findings in dysphagic patients with cricopharyngeal dysfunction: before and after open cricopharyngeal myotomy. Ann Otol Rhinol Laryngol. 2007;116(1):49–56.

    Article  PubMed  Google Scholar 

  79. Muraji T, Takamizawa S, Satoh S, Nishijima E, Tsugawa C, Tamura A, Shimizu N. Congenital cricopharyngeal achalasia: diagnosis and surgical management. J Pediatr Surg. 2002;37(5):12–4.

    Article  Google Scholar 

  80. Blitzer A, Brin MF. Use of botulinum toxin for diagnosis and management of cricopharyngeal achalasia. Otolaryngol Head Neck Surg. 1997;116(3):328–30.

    Article  CAS  PubMed  Google Scholar 

  81. Patti MG, Gorodner MV, Galvani C, Tedesco P, Fisichella PM, Ostroff JW, Bagatelos KC, Way LW. Spectrum of esophageal motility disorders. Arch Surg. 2005;140:442–9.

    Article  PubMed  Google Scholar 

  82. Hussain SZ, Thomas R, Tolia V. A review of achalasia in 33 children. Dig Dis Sci. 2002;47(11):2538–43.

    Article  CAS  PubMed  Google Scholar 

  83. Adler DG, Romero Y. Primary esophageal motility disorders. Mayo Clin Proc. 2001;76(2):195–200.

    Article  CAS  PubMed  Google Scholar 

  84. Nguyen HN, Domingues GR, Winograd R, Lammert F, Silny J, Matern S. Impedance characteristics of esophageal motor function in achalasia. Dis Esophagus. 2004;17:44–50.

    Article  CAS  PubMed  Google Scholar 

  85. Meneghelli UG, Peria FM, Darezzo FMR, Almeida FH, Rodrigues CM, Aprile LRO, Dantas RO. Clinical, radiographic, and manometric evolution of esophageal involvement of chagas’ disease. Dysphagia. 2005;20:40–5.

    Article  PubMed  Google Scholar 

  86. Prpic I, Huebner A, Persic M, Handschug K, Pavletic M. Triple a syndrome: genotype-phenotype assessment. Clin Genet. 2003;63(5):415–7.

    Google Scholar 

  87. Committee SPC. Ssat patient care guidelines: esophageal achalasia. J Gastrointest Surg. 2007;11:1210–2.

    Article  Google Scholar 

  88. SSAT. Esophageal achalasia. Ssat patient care guidelines. J Gastrointest Surg. 2004;8(3):367–8.

    Article  Google Scholar 

  89. Pandolfino JE, Kwiatek MA, Nealis T, Blusiewicz W, Post J, Kahrilas PJ. Achalasia: a new clinically relevant classification by high-resolution manometry. Gastroenterology. 2008;135:1526–33.

    Article  PubMed  PubMed Central  Google Scholar 

  90. Agrawal A, Hila A, Tutuian R, Castell DO. Manometry and impedance characteristics of achalasia: facts and myths. J Clin Gastroenterol. 2008;42(3):266–70.

    PubMed  Google Scholar 

  91. Chung J-J, Park HJ, Yu JS, Hong YJ, Kim JH, Kim M-J, Lee SI. A comparison of esophagography and esophageal transit scintigraphy in the evaluation of usefulness of endoscopic pneumatic dilatation in achalasia. ACTA Radiol. 2008;49:498–505.

    Article  PubMed  Google Scholar 

  92. Levine MS, Rubesin SE. Diseases of the esophagus: diagnosis with esophagography. Radiology. 2005;237:414–27.

    Article  PubMed  Google Scholar 

  93. Smout AJPM. Advances in esophageal motor disorder. Curr Opin Gastroenterol. 2008;24:285–9.

    Article  Google Scholar 

  94. Levine MS, Rubesin SE, Laufer I. Barium esophagography: a study for all seasons. Clin Gastroenterol Hepatol. 2008;6(1):11–25.

    Article  PubMed  Google Scholar 

  95. Herbella FAM, Razx DJ, Nipomnick I, Patti MG. Primary versus secondary esophageal motility disorders: diagnosis and implications for treatment. J Laparoendosc Adv Surg Tech. 2009;19(2):195–8.

    Article  Google Scholar 

  96. Grubel C, Borovicka J, Schwizer W, Fox M, Hebbard G. Diffuse esophageal spasm. Am J Gastroenterol. 2008;103:450–7.

    Article  PubMed  Google Scholar 

  97. Konturek T, Lembo A. Spasm, nutcracker, and iem: real or manometry findings? J Clin Gastroenterol. 2008;42(5):647–51.

    Article  PubMed  Google Scholar 

  98. Tutuian R, Castell DO. Review article: oesophageal spasms – diagnosis and management. Aliment Pharmacol Ther. 2006;23(10):1393–402.

    Article  CAS  PubMed  Google Scholar 

  99. Allen ML, DiMarino AJ. Manometric diagnosis of diffuse esophageal spasm. Dig Dis Sci. 1996;41(7):1346–9.

    Article  CAS  PubMed  Google Scholar 

  100. Agrawal A, Hila A, Tutuian R, Mainie I, Castell D. Clinical relevance of the nutcracker esophagus: suggested revision of criteria for diagnosis. J Clin Gastroenterol. 2006;40(6):504–9.

    Article  PubMed  Google Scholar 

  101. Richter JE, Spurling TJ, Cordova CM, Castell DO. Effects of oral calcium blocker, diltiazem, on esophageal contractions. Studies in volunteers and patients with nutcracker esophagus. Dig Dis Sci. 1984;29(7):649–56.

    Article  CAS  PubMed  Google Scholar 

  102. Chitkara DK, Fortunato C, Nurko S. Esophageal motor activity in children with gastro-esophageal reflux disease and esophagitis. J Pediatr Gastroenterol Nutr. 2005;40(1):70–5.

    Article  PubMed  Google Scholar 

  103. Calderaro DC, de Carvalho MA, Moretzsohn LD. Esophageal manometry in 28 systemic sclerosis Brazilian patients: findings and correlations. Dis Esophagus. 2009;22(8):700–4.

    Google Scholar 

  104. Lahcene M, Oumnia N, Matougui N, Boudjella M, Tebaibia A, Touchene B. Esophageal dysmotility in scleroderma: a prospective study of 183 cases. Gastroenterol Clin Biol. 2009;33(6–7):466–9.

    Google Scholar 

  105. Edenbrandt L, Theander E, Hogstrom M, Scheja A, Akesson A, Palmer J. Esophageal scintigraphy of systemic sclerosis. J Nucl Med. 1995;36:1533–8.

    CAS  PubMed  Google Scholar 

  106. Sallam H, McNearney TA, Chen JD. Systematic review: pathophysiology and management of gastrointestinal dysmotility in systemic sclerosis (scleroderma). Aliment Pharmacol Ther. 2006;23(6):691–712.

    Google Scholar 

  107. Del Giudice E, Staiano A, Capano G, Romano A, Florimonte L, Miele E, Ciarla C, Campanozzi A, Crisanti AF. Gastrointestinal manifestations in children with cerebral palsy. Brain Dev. 1999;21(5):307–11.

    Google Scholar 

  108. Eckardt VF, Nix W, Kraus W, Bohl J. Esophageal motor function in patients with muscular dystrophy. Gastroenterology. 1986;90(3):628–35.

    Google Scholar 

  109. Modolell I, Mearin F, Baudet JS, Gamez J, Cervera C, Malagelada JR. Pharyngo-esophageal motility disturbances in patients with myotonic dystrophy. Scand J Gastroenterol. 1999;34(9):878–82.

    Article  CAS  PubMed  Google Scholar 

  110. Lecointe-Besancon I, Leroy F, Devroede G, Chevrollier M, Lebeurier F, Congard P, Arhan P. A comparative study of esophageal and anorectal motility in myotonic dystrophy. Dig Dis Sci. 1999;44(6):1090–9.

    Article  CAS  PubMed  Google Scholar 

  111. Staiano A, Del Giudice E, Romano A, Andreotti MR, Santoro L, Marsullo G, Rippa PG, Iovine A, Salvatore M. Upper gastrointestinal tract motility in children with progressive muscular dystrophy. J Pediatr. 1992;121(5 Pt 1):720–4.

    Article  CAS  PubMed  Google Scholar 

  112. Camelo AL, Awad RA, Madrazo A, Aguilar F. Esophageal motility disorders in mexican patients with duchenne’s muscular dystrophy. Acta Gastroenterol Latinoam. 1997;27(3):119–22.

    CAS  PubMed  Google Scholar 

  113. Zarate N, Mearin F, Gil-Vernet JM, Camarasa F, Malagelada JR. Achalasia and down’s syndrome: coincidental association or something else? Am J Gastroenterol. 1999;94(6):1674–7.

    Google Scholar 

  114. Zarate N, Mearin F, Hidalgo A, Malagelada J-R. Prospective evaluation of esophageal motor dysfunction in down’s syndrome. Am J Gastroenterol. 2001;96(6):1718–24.

    Article  CAS  PubMed  Google Scholar 

  115. Nurko S, Rosen R. Esophageal dysmotility in patients who have eosinophilic esophagitis. Gastrointest Endoscopic Clin N Am. 2008;18:73–89.

    Article  Google Scholar 

  116. Nurko S, Rosen R, Furuta GT. Esophageal dysmotility in children with eosinophilic esophagitis: a study using prolonged esophageal manometry. Am J Gastroenterol. 2009;104(12):3050–7.

    Google Scholar 

  117. Hejazi RA, Reddymasu SC, Sostarich S, McCallum RW. Disturbances of esophageal motility in eosinophilic esophagitis: a case series. Dysphagia: Published online: 26 Aug 2009.

    Google Scholar 

  118. Fass R, Landau O, Kovacs TOG, Ippoliti AF. Esophageal motility abnormalities in cirrhotic patients before and after endoscopic variceal treatment. Am J Gastroenterol. 1997;92(6):941–6.

    CAS  PubMed  Google Scholar 

  119. Genc A, Mutaf O. Esophageal motility changes in acute and late periods of caustic esophageal burns and their relation to prognosis in children. J Pediatr Surg. 2002;37(11):1526–8.

    Article  PubMed  Google Scholar 

  120. Dantas RO, Mamede RC. Esophageal motility in patients with esophageal caustic injury. Am J Gastroenterol. 1996;91(6):1157–61.

    CAS  PubMed  Google Scholar 

  121. Jadcherla SR, Gupta A, Stoner E, Fernandez S, Caniano D, Rudolph CD. Neuromotor markers of esophageal motility in feeding intolerant infants with gastroschisis. J Pediatr Gastroenterol Nutr. 2008;47(2):158–64.

    Article  PubMed  Google Scholar 

  122. Shono T, Sulta S, Arima T, Handa N, Ishii K, Hirose R, Sakaguchi T. Motility function of the esophagus before primary anastomosis in esophageal atresia. J Pediatr Surg. 1993;28(5):673–6.

    Article  CAS  PubMed  Google Scholar 

  123. Tugay M, Yildiz F, Utkan T, Ulak G, Gacar N, Erden F. Impaired esophageal reactivity in adriamycin-induced rat esophageal atresia: an in vitro study. J Pediatr Surg. 2001;36(10):1569–73.

    Google Scholar 

  124. Qi BQ, Merei J, Farmer P, Hasthorpe S, Myers NA, Beasley SW, Hutson JM. The vagus and recurrent laryngeal nerves in the rodent experimental model of esophageal atresia. J Pediatr Surg. 1997;32(11):1580–6.

    Google Scholar 

  125. Kawahara H, Kubota A, Hasegawa T, Okuyama H, Ueno T, Watanabe T, Morshita Y, Saka R, Fukuzawa M. Lack of distal esophageal contractions is a key determinant of gastroesophageal reflux disease after repair of esophageal atresia. J Pediatr Surg. 2007;42:2017–21.

    Article  PubMed  Google Scholar 

  126. Dutta HK, Grover VP, Dwivedi SN, Bhatnagar V. Manometric evaluation of postoperative patients of esophageal atresia and tracheo-esophageal fistula. Eur J Pediatr Surg. 2001;11(6):371–6.

    Google Scholar 

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Authors and Affiliations

  1. Division of Pediatric Gastroenterology, Ohio State University College of Medicine, Nationwide Children’s Hospital, 700 Children’s Drive, JW 1985, Columbus, OH, 43205, USA

    Hayat M. Mousa MD, FAAP

  2. Department of Pediatrics, Federal University of Sao Paulo, Sao Paulo, Brazil

    Rodrigo Machado MD, PhD

Authors
  1. Hayat M. Mousa MD, FAAP
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  2. Rodrigo Machado MD, PhD
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Correspondence to Hayat M. Mousa MD, FAAP .

Editor information

Editors and Affiliations

  1. Medical University of Graz, Graz, Austria

    Holger Till

  2. Sheffield Children’s Hospital, Paediatric Gastroenterology Centre, Sheffield, United Kingdom

    Mike Thomson

  3. Division of Cardiothoracic Surgery, Department of Surgery, University of Minnesota Medical School, Minneapolis, Minnesota, USA

    John E. Foker

  4. Department Surgery, University of Missouri, Kansas City Children’s Mercy Hospital, Kansas City, Missouri, USA

    George W. Holcomb III

  5. University of Arizona, Tucson, Arizona, USA

    Khalid M. Khan

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Mousa, H.M., Machado, R. (2017). Esophageal Motility. In: Till, H., Thomson, M., Foker, J., Holcomb III, G., Khan, K. (eds) Esophageal and Gastric Disorders in Infancy and Childhood. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-11202-7_4

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  • DOI: https://doi.org/10.1007/978-3-642-11202-7_4

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