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Endometrial Carcinoma

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Diagnosis of Endometrial Biopsies and Curettings

Abstract

Endometrial carcinoma is the 4th most common cancer for American women and the most common malignant tumor of the female genital tract. In the United States in 2015, there were 54,644 new cases and 10,096 deaths resulting from this neoplasm. Black women have a much higher rate of mortality when compared to white women. Although most endometrial carcinomas that are diagnosed at early stages have an excellent survival rate, this neoplasm represents a biologically and morphologically diverse group of tumors, with differing pathogenesis, behavior, and prognosis. These tumors were grouped into two types based on clinicopathologic features designated “Type I and Type II”. This grouping was helpful in understanding the pathogenesis of endometrial cancer, but it is important to understand that this is not a histopathologic classification. The prototypic Type I tumor is the usual type of endometrioid carcinoma, and the prototypic Type II tumor is serous carcinoma.

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Authors and Affiliations

  1. Department of Pathology, The Johns Hopkins Hospital, Baltimore, MD, USA

    Tricia A. Murdock, Emanuela F. T. Veras & Robert J. Kurman

  2. Department of Pathology and Laboratory Medicine, State University of New York Upstate Medical University, Syracuse, NY, USA

    Michael T. Mazur

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Murdock, T.A., Veras, E.F.T., Kurman, R.J., Mazur, M.T. (2019). Endometrial Carcinoma. In: Diagnosis of Endometrial Biopsies and Curettings. Springer, Cham. https://doi.org/10.1007/978-3-319-98608-1_10

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