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Unusual form of superficial spreading squamous cell carcinoma of cervix involving the endometrium, bilateral tubes and ovaries: a case report with literature review

  • Gynecologic Oncology
  • Published:
Archives of Gynecology and Obstetrics Aims and scope Submit manuscript

Abstract

Objective

Although the majority of metastatic ovarian tumors arise within the female genital tract, squamous cell carcinoma of the cervix is a rare form of metastases to the bilateral ovaries by endometrial and transtubal spreading.

Case

A 53-year-old woman was referred to the oncology clinic with postmenopausal bleeding. On vaginal examination, a 3 cm tumor arising from the cervix was inspected. Multiple cervical biopsies and endocervical curettage revealed large cell, non-keratinized squamous cell cervix carcinoma. Radical hysterectomy and bilateral salpingo-oophorectomy were performed. Bilateral pelvic and para-aortic lymph nodes were also removed. The final pathology report revealed endometrial, focal myometrial, bilateral tubal mucosal, fimbrial and bilateral ovarian squamous cell carcinoma involvement. Pelvic and para-aortic nodes were free from metastases.

Conclusion

Although the incidence of ovarian metastases of adenocarcinoma of the cervix is significantly higher, squamous cell carcinoma may also metastasize to the ovaries by endometrial and transtubal spreading in the absence of lymph node involvement. Especially in young patients for whom preservation of the ovaries is supposed, gross intraoperative inspection of the radical hysterectomy specimen and endometrium should be done and ovaries should be evaluated carefully.

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Acknowledgments

The present case was presented in part (poster presentation) at the 16th International Meeting of the European Society of Gynecological Oncology (ESGO), which was held in Belgrade, Serbia, 2009.

Conflict of interest

We declare that we have no conflict of interest.

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Authors and Affiliations

  1. Department of Gynecologic Oncology, Zekai Tahir Burak Women’s Health Education and Research Hospital, Zekai Tahir Burak Kadin Sagligi Egitim ve Arastirma Hastanesi Cebeci, Ankara, Turkey

    Tayfun Gungor, Sunduz Ozlem Altinkaya, Mustafa Ozat & Leyla Mollamahmutoglu

  2. Yali Mahallesi 6330 Sokak Cagdas Apt. 4/2, Karsiyaka, Izmir, Turkey

    Sunduz Ozlem Altinkaya

  3. Department of Pathology, Zekai Tahir Burak Women’s Health Education and Research Hospital, Ankara, Turkey

    Serap Akbay

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  1. Tayfun Gungor
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  2. Sunduz Ozlem Altinkaya
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  3. Mustafa Ozat
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  5. Leyla Mollamahmutoglu
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Correspondence to Sunduz Ozlem Altinkaya.

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Gungor, T., Altinkaya, S.O., Ozat, M. et al. Unusual form of superficial spreading squamous cell carcinoma of cervix involving the endometrium, bilateral tubes and ovaries: a case report with literature review. Arch Gynecol Obstet 283, 323–327 (2011). https://doi.org/10.1007/s00404-010-1672-1

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  • DOI: https://doi.org/10.1007/s00404-010-1672-1

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