Abstract
The integration of nanotechnology in the sensor technology open ups the possibility for a wide variety of applications, such as micropollutants detection. Micropollutants are emerging as a new challenge to the scientific community, where the growing number of pollutants requires the development of innovative analytical devices that are precise, sensitive, specific, rapid, and easy-to-use to meet the increasing demand for environmental pollution control. Nanobiosensors, as a powerful alternative to conventional analytical techniques, enable the highly sensitive, real-time, and high-frequency monitoring of micropollutants without extensive sample preparation. Since nanobiosensor holds the possibility of detecting and manipulating atoms and molecules using nanodevices, which have led to the development of biosensors that interact with extremely small molecules that need to be analyzed, such as micropollutants.
This chapter reviews important advances in nanobiosensor structures based functionalized nanoparticles, nanotubes, and nanowires with biorecognition materials (e.g., enzymes, aptamers, DNAzymes, antibodies and whole cells) that facilitate the increasing application of nanobiosensors for detection of micropulutants. Nanomaterials such as gold nanoparticles, carbon nanotubes, magnetic nanoparticles and quantum dots have been actively studied for nanobiosensors. The use of nanoparticle-functionalized surfaces can drastically boost the specificity of the detection system, that make nanobiosensor becomes more refined and reliable. It will eventually make small devices for rapid screening of a wide variety of micropollutants with very low sensitivity and selectivity at low cost, which has become a new interdisciplinary frontier between chemical or biological detection, material science, and chemistry.
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The author gratefully thank the DRPM, Ministry of Research, Technology and Higher Education, the Republic of Indonesia for supporting this work via International Research Collaboration and Scientific Publication 2017 (Hibah Penelitian Kerjasama Luar Negeri dan Publikasi Internasional 2017) and thank to Prof. M. Ahmad, FST USIM Malaysisa, for valuable discussion regarding this work.
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Kuswandi, B. (2018). Nanobiosensors for Detection of Micropollutants. In: Dasgupta, N., Ranjan, S., Lichtfouse, E. (eds) Environmental Nanotechnology. Environmental Chemistry for a Sustainable World, vol 14. Springer, Cham. https://doi.org/10.1007/978-3-319-76090-2_4
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