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Biopolymers Nanofibers for Biomedical Applications and Environmental Applications

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Electrospun Biomaterials and Related Technologies

Abstract

Electrospinning is a manufacturing technique of growing interest by its versatility in the generation of membranes constituted by fibers. Its relevance has been evidenced by the growing number of researches conducted in the recent years in the field of biotechnology and nanotechnology. In the field of biotechnology, the research interest has been focused in the development of tridimensional assemblies from biocompatible polymers and biopolymers which are able to mimics biological structures and functions for use in tissue regeneration, wound healing, drug delivery, among other applications. In the environmental protection field, the use of electrospun biopolymers has been favored by the feasibility to functionalize them to improve its behavior as adsorbent material, filter or catalyst in the decomposition of toxic compounds while keeping its biodegradability.

This review will provide an overview on the electrospinning parameters, focusing in the processing and the stabilization conditions for nanofibers synthesized from biopolymers such as chitosan, collagen, alginate and gelatin. The results of some promising researches in biomedical and environmental applications using these biopolymers will be also summarized here.

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Abbreviations

BDDGE:

1,4-butanediol diglycidyl ether

BSA:

Bovine serum albumin

CLSM:

Confocal laser scanning microscopy

CNCs:

Cellulose nanocrystals

DMAc:

Dimethylacetamide

DMEM:

Dulbecco’s modified Eagle’s medium

DMF:

Dimethylformamide

DMSO:

Dimethyl sulfoxide

E. coli :

Escherichia coli

EC:

Endothelial cells

EDC:

1-ethyl-3-(3-dimethylaminopropyl) carbodiimide

FTIR:

Fourier-transform infrared spectroscopy

GRGDSP:

Glycine–arginine–glycine–aspartic acid–serine–proline

HAP:

Hydroxyapatite

HDFCs:

Human dental follicle cells

HFIP:

Hexafluoroisopropanol

HFP:

1,1,1,3,3,3-hexafluoro-2-propanol

hMSCs:

Human mesenchymal stem cells

HTCC:

N-[(2-hydroxyl-3-trimethylammonium) propyl] chitosan

ICP–AES:

Inductively Coupled Plasma Atomic Emission Spectroscopy

MIC:

Minimal inhibitory concentration

NMR:

Nuclear magnetic resonance

P. aureginosa :

Pseudomona aureginosa

PBS:

Phosphate buffer solution

PCL:

Poly(caprolactone)

PEO:

Poly(ethylene oxide)

PLA:

Poly(lactic acid)

PPV:

Porcine parvovirus

PVA:

Poly(vinyl alcohol)

S-aureus :

Staphylococcus aureus

SDS:

Sodium dodecyl sulphate

SHP:

Sodium hypophosphite monohydrate

SMC:

Smooth muscle cells

TEM:

Transmission electron microscopy

TFA:

Trifluoroacetic acid

TFE:

Trifluoroethanol

THF:

Tetrahydrofuran

WVTR:

Water vapor transmission rate

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Author information

Authors and Affiliations

  1. Chemistry Department, University of Puerto Rico, Mayagüez, Puerto Rico

    Ana L. Vega-Avila

  2. Department of Engineering Science and Materials, University of Puerto Rico, Mayagüez, Puerto Rico

    Oscar Perales-Perez

  3. Mechanical Engineering Department, University of Puerto Rico, Mayagüez, Puerto Rico

    Ricky Valentín Rullan

Authors
  1. Ana L. Vega-Avila
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  2. Oscar Perales-Perez
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  3. Ricky Valentín Rullan
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Corresponding author

Correspondence to Oscar Perales-Perez .

Editor information

Editors and Affiliations

  1. Department of Chemical Engineering, University of Puerto Rico Mayaguez, Mayaguez, Puerto Rico, Puerto Rico

    Jorge Almodovar

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Vega-Avila, A.L., Perales-Perez, O., Valentín Rullan, R. (2017). Biopolymers Nanofibers for Biomedical Applications and Environmental Applications. In: Almodovar, J. (eds) Electrospun Biomaterials and Related Technologies. Springer, Cham. https://doi.org/10.1007/978-3-319-70049-6_4

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