Skip to main content

Endoscopic Treatment of Internal Hemorrhoids

  • Reference work entry
  • First Online:
Hemorrhoids

Part of the book series: Coloproctology ((COLOPROCT,volume 2))

  • 1005 Accesses

Abstract

Hemorrhoids represent pathological changes in the physiological anal cushions and are one of the most common ano-rectal diseases. Hemorrhoids are divided in two main groups, internal and external. Internal hemorrhoidal complexes are furthermore conventionally categorized in IV grades according to their extent, tendency to prolapse, and reducibility (Goligher’s classification). Regardless to pathogenesis, the appropriate assessment of hemorrhoids is crucial to treatment. Once nonhemorrhoidal reasons for complaints have been ruled out, patients suffering from symptomatic low-graded internal hemorrhoids are initially best served with medical conservative behavioral approach with the aim of relief symptoms. When conservative treatments fail, patients are amenable to nonsurgical ablative office-based procedures. Rubber band ligation, injection sclerotherapy, and infrared coagulation are the three viable evidence-based treatment alternatives. These treatment modalities are well-established, relatively well-tolerated, almost effective, and furthermore repeatable procedures and can be performed using an anoscope or proctoscope or during flexible endoscopy, the latter with substantial advantages and minimal or no adjunctive equipment. According to the available literature, rubber band ligation is associated with better long-term efficacy and lower sessions needed for treatment with acceptable complication rates and is therefore advised as the first-line treatment option. However, sclerotherapy and infrared thermocoagulation may still be suitable in specific circumstances and subset of patients. Despite grade of disease and patients’ conditions and expectations, the choice between the different options ultimately depends on local expertise, preferences, and facilities.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 419.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Hardcover Book
USD 329.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  • Adami B, Eckardt VF, Suermann RB, Karbach U, Ewe K (1981) Bacteremia after proctoscopy and hemorrhoidal injection sclerotherapy. Dis Colon Rectum 24:373–374

    Article  CAS  PubMed  Google Scholar 

  • Albuquerque A (2016) Rubber band ligation of hemorrhoids: a guide for complication. World J Gastrointest Surg 27:614–620

    Article  Google Scholar 

  • Altomare DF, Roveran A, Pecorella G, Gaj F, Stortini E (2006) Guidelines of Italian Society of Colo-Rectal surgery. Tech Coloproctol 10:181–186

    Article  CAS  PubMed  Google Scholar 

  • ASGE Technology Assessment Committee, Croffie J, Somogyi L, Chuttani R, DiSario J, Liu J, Mishkin D, Shah RJ, Tierney W, Wong Kee Song LM, Petersen BT (2007) Sclerosing agents for use in GI endoscopy. Gastrointest Endosc 66:1–6

    Article  Google Scholar 

  • ASGE Technology Committee, Siddiqui UD, Barth BA, Banerjee S, Bhat YM, Chauhan SS, Gottlieb KT, Konda V, Maple JT, Murad FM, Pfau P, Pleskow D, Tokar JL, Wang A, Rodriguez SA (2014) Devices for the endoscopic treatment of hemorrhoids. Gastrointest Endosc 79:8–14

    Article  Google Scholar 

  • Beattie GC, Wilson RG, Loudon MA (2002) The contemporary management of hemorrhoids. Color Dis 4:450–454

    Article  CAS  Google Scholar 

  • Benin P, D’Amico C (2007) Foam sclerotherapy with Fibrovein (STD) for the treatment of hemorrhoids, using a flexible endoscope. Minerva Chir 62:235–240

    PubMed  CAS  Google Scholar 

  • Berkelhammer C, Moosvi SB (2002) Retroflected endoscopic band ligation of bleeding internal hemorrhoids. Gastrointest Endosc 55:532–537

    Article  PubMed  Google Scholar 

  • Blaisdell PC (1958) Office ligation of internal haemorrhoids. Am J Surg 96:401–404

    Article  CAS  PubMed  Google Scholar 

  • Brown SR, Tiernan JP, Watson AJM, Biggs K, Shephard N, Wailoo AJ, Bradburn M, Hind AAD (2016) Hemorrhoidal artery ligation versus rubber band ligation for the management of symptomatic second degree and third degree hemorrhoids (HubBLe): a multicentre, open-label, randomised controlled trial. Lancet 388:356–364

    Article  PubMed  PubMed Central  Google Scholar 

  • Cazemier M, Felt-Bersma RJF, Cuesta MA, Mulder CJJ (2007) Elastic band ligation of hemorroids: flexible gastroscope or rigid proctoscope? World J Gastroenterol 13:585–587

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Chew SS, Marshall L, Kalish L, Tham J, Grieve DA, Douglas PR, Newstead GL (2003) Short-term and long-term results of combined sclerotherapy and rubber band ligation of hemorrhoids and mucosal prolapse. Dis Colon Rectum 46:1232–1237

    Article  PubMed  Google Scholar 

  • Chiappone GM, Malpas PM (1992) Endoscopic retrograde haemorrhoidal sclerotherapy. Gastroenterol Nurs 15:78–80

    Article  CAS  PubMed  Google Scholar 

  • Cocorullo G, Tutino R, Falco N, Licari L, Orlando G, Fontana T, Raspanti C, Salamone G, Scerrino G, Gallo G, Trompetto M, Gulotta G (2017) The non-surgical management for hemorrhoidal disease. A systematic review. G Chir 38:5–14

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Dennison A, Whiston RJ, Rooney S, Chadderton RD, Wherry DC, Morris DL (1990) A randomized comparison of infrared photocoagulation with bipolar diathermy for the outpatient treatment of hemorrhoids. Dis Colon Rectum 33:32–34

    Article  CAS  PubMed  Google Scholar 

  • Elram R, Wasserberg N (2007) Anorectal necrosis induced by injection sclerotherapy for hemorrhoids. Int J Color Dis 22:997–998

    Article  Google Scholar 

  • Fukuda A, Kajiyama T, Arakawa H, Kishimoto H, Someda H, Sakai M, Tsunekawa S, Chiba T (2004) Retroflected endoscopic multiple band ligation of symptomatic internal hemorrhoids. Gastrointest Endosc 59:380–384

    Article  PubMed  Google Scholar 

  • Ganz RA (2013) The evaluation and treatment of hemorrhoids: a guide for the gastroenterologist. Clin Gastroenterol Epatol 11:593–603

    Article  Google Scholar 

  • Goligher JC (1980) Haemorrhoids or piles. In: Goligher JC (ed) Surgery of the anus, rectum and colon, 4th edn. Bailliere Tindall, London, p 96

    Google Scholar 

  • Greca F, Hares MM, Nevah E, Alexander-Williams J, Keighley MR (1981) A randomized trial to compare rubber band ligation with phenol injection for treatment of haemorrhoids. Br J Surg 68:250–252

    Article  CAS  PubMed  Google Scholar 

  • Higuero T, Abramowitz L, Castinel A, Fathallah N, Hemery P, Laclotte Duhoux C, Pigot F, Pillant-Le Moult H, SenĂ©joux A, Siproudhis L, Staumont G, Suduca JM, Vinson-Bonnet B (2016) Guidelines for the treatment of hemorrhoids (short report). J Visc Surg 153:213–218

    Article  CAS  PubMed  Google Scholar 

  • Hollingshead JRF, Phillips RK (2016) Haemorrhoids: modern diagnosis and treatment. Postgrad Med J 92:4–8

    Article  CAS  PubMed  Google Scholar 

  • Jacobs D (2014) Clinical practice. Hemorrhoids. N Engl J Med 37:944–951

    Article  CAS  Google Scholar 

  • Jalihal U, Satya Prakash BS, Avinash B, Karanth D (2013) Colonoscopic band ligation for internal hemorrhoids – a tertiary care experience. J Dig Endosc 4:6–9

    Google Scholar 

  • Johanson JF, Rimm A (1992) Optimal nonsurgical treatment of hemorrhoids: a comparative analysis of infrared coagulation, rubber band ligation, and injection sclerotherapy. Am J Gastroenterol 87:1600–1606

    PubMed  CAS  Google Scholar 

  • Kanellos I, Goulimaris I, Vakalis I, Dadoukis I (2000) Long-term evaluation of sclerotherapy for haemorrhoids. A prospective study. Int J Surg Investig 2:295–298

    PubMed  CAS  Google Scholar 

  • Kanellos I, Goulimaris I, Christoforidis E, Kelpis T, Betsis D (2003) A comparison of the simultaneous application of sclerotherapy and rubber band ligation, with sclerotherapy and rubber band ligation applied separately, for the treatment of haemorrhoids: a prospective randomized trial. Color Dis 5:133–138

    Article  CAS  Google Scholar 

  • Lohsiriwat V (2012) Hemorrhoids: from basic pathophysiology to clinical management. World J Gastroenterol 18:2009–2017

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Lohsiriwat V (2015) Treatment of hemorrhoids: a coloproctologist’s view. World J Gastroenterol 21:9245–9252

    Article  PubMed  PubMed Central  Google Scholar 

  • Lohsiriwat V (2016) Anorectal emergencies. World J Gastroenterol 22:5867–5878

    Article  PubMed  PubMed Central  Google Scholar 

  • MacRae HM, McLeod RS (1995) Comparison of hemorrhoidal treatment modalities. A meta-analysis. Dis Colon Rectum 38:687–694

    Article  CAS  PubMed  Google Scholar 

  • MacRae HM, McLeod RS (1997) Comparison of hemorrhoidal treatments: a meta-analysis. Can J Surg 40:14–17

    PubMed  PubMed Central  CAS  Google Scholar 

  • Marti M-C (2013) Hemorrhoids. In: Marti MC, Givel GC (eds) Surgery of anorectal diseases: with pre- and postoperative management. Springer-Verlag Berlin Heidelberg, pp 59–60

    Google Scholar 

  • McLemore EC, Rai R, Siddiqui J, Basu PP, Tabbaa M, Epstein MS (2012) Novel endoscopic delivery modality of infrared coagulation therapy for internal hemorrhoids. Surg Endosc 26:3082–3087

    Article  PubMed  PubMed Central  Google Scholar 

  • Moser KH, Mosch C, Walgenbach M, Bussen DG, Kirsch J, Joos AK, Gliem P, Sauerland S (2013) Efficacy and safety of sclerotherapy with polidocanol foam in comparison with fluid sclerosant in the treatment of first-grade haemorrhoidal disease: a randomised, controlled, single-blind, multicentre trial. Int J Color Dis 28:1439–1447

    Article  Google Scholar 

  • Murray-Lyon IM, Kirkham JS (2001) Hepatic abscesses complicating injection sclerotherapy of haemorrhoids. Eur J Gastroenterol Hepatol 13:971–972

    Article  CAS  PubMed  Google Scholar 

  • Nelson RS, Ewing BM, Ternent C, Shashidharan M, Blatchford GJ, Thorson AG (2008) Risk of late bleeding following hemorrhoidal banding in patients on antithrombotic prophylaxis. Am J Surg 196:994–999

    Article  PubMed  Google Scholar 

  • Nijhawan S, Udawat H, Gupta G, Sharma A, Mathur A, Sapra B, Nepalia S (2011) Flexible video-endoscopic injection sclerotherapy for second and third degree internal hemorrhoids. J Dig Endosc 2:1–5

    Google Scholar 

  • Ono T, Goto K, Takagi S, Iwasaki S, Komatsu H (2005) Sclerosing effect of OC-108, a novel agent for hemorrhoids, is associated with granulomatous inflammation induced by aluminum. J Pharmacol Sci 99:353–363

    Article  CAS  PubMed  Google Scholar 

  • Ponsky JL, Mellinger JD, Simon IB (1991) Endoscopic retrograde hemorrhoidal sclerotherapy using 23.4% saline: a preliminary report. Gastrointest Endosc 37:155–158

    Article  CAS  PubMed  Google Scholar 

  • Rivadeneira DE, Steele SR, Ternent C, Chalasani S, Buie WD, Rafferty JL, on behalf of the Standards Practice Task Force of The American Society of Colon and Rectal Surgeons (2011) Practice parameters for the management of hemorrhoids (revised 2010). Dis Colon Rectum 54:1059–1064

    Article  PubMed  Google Scholar 

  • Santos G, Novell JR, Khoury G, Winslet MC, Lewis AA (1993) Long-term results of large-dose, single-session phenol injection sclerotherapy for hemorrhoids. Dis Colon Rectum 36:958–961

    Article  CAS  PubMed  Google Scholar 

  • Schulte T, Fändrich F, Kahlke V (2008) Life-threatening rectal necrosis after injection sclerotherapy for haemorrhoids. Int J Color Dis 23:725–726

    Article  CAS  Google Scholar 

  • Senapati A, Nicholls RJ (1988) A randomised trial to compare the results of injection sclerotherapy with a bulk laxative alone in the treatment of bleeding haemorrhoids. Int J Color Dis 3:124–126

    Article  CAS  Google Scholar 

  • Shanmugam V, Hakeem A, Campbell KL, Rabindranath KS, Steele RJC, Thaha MA, Loudon MA (2005) Rubber band ligation versus excisional hemorrhoidectomy for hemorrhoids. Cochrane database syst rev 20(3):CD005034

    Google Scholar 

  • Society for Surgery of the Alimentary Tract (SSAT): Patient Care Guidelines – Surgical management of hemorrhoids (Revised & Board Approved 10/13/08) www.ssat.com

  • Stiegmann GV, Goff JS, Sun JH, Davis D, Bozdech J (1989) Endoscopic variceal ligation: an alternative to sclerotherapy. Gastrointest Endosc 35:431–434

    Article  CAS  PubMed  Google Scholar 

  • Su MY, Chiu CT, Wu CS, Ho YP, Lien JM, Tung SY, Chen PC (2003a) Endoscopic hemorroidal ligation of symptomatic internal hemorrhoids. Gastrointest Endosc 58:871–874

    Article  PubMed  Google Scholar 

  • Su MY, Tung SY, Wu CS, Sheen IS, Chen PC, Chiu CT (2003b) Long-term results of endoscopic hemorrhoidal ligation: two different devices with similar results. Endoscopy 35:416–420

    Article  PubMed  Google Scholar 

  • Su M-Y, Chiu C-t, Lin W-P, Hsu C-M, Chen P-C (2011) Long term outcome and efficacy of endoscopic hemorrhoid ligation for symptomatic internal hemorrhoids. World J Gastroenterol 17:2431–2436

    Article  PubMed  PubMed Central  Google Scholar 

  • Suh YJ, Ha HK, Oh HK, Shin R, Jeong SY, Park KJ (2013) Rectal perforation caused by anal stricture after hemorrhoid treatment. Ann Coloproctol 29:28–30

    Article  PubMed  PubMed Central  Google Scholar 

  • Takano M, Iwadare J, Ohba H, Takamura H, Masuda Y, Matsuo K, Kanai T, Ieda H, Hattori Y, Kurata S, Koganezawa S, Hamano K, Tsuchiya S (2006) Sclerosing therapy of internal hemorrhoids with a novel sclerosing agent. Comparison with ligation and excision. Int J Color Dis 21:44–51

    Article  CAS  Google Scholar 

  • Templeton JL, Spence RA, Kennedy TL, Parks TG, Mackenzie G, Hanna WA (1983) Comparison of infrared coagulation and rubber band ligation for first and second degree haemorrhoids: a randomised prospective clinical trial. Br Med J (Clin Res Ed) 286:1387–1389

    Article  CAS  Google Scholar 

  • Tokunaga Y, Sasaki H (2013) Impact of less invasive treatments including sclerotherapy with a new agent and hemorrhoidopexy for prolapsing internal hemorrhoids. Int Surg 98:210–213

    Article  PubMed  PubMed Central  Google Scholar 

  • Tomiki Y, Ono S, Aoki J, Takahashi R, Ishiyama S, Sugimoto K, Yaginuma Y, Kojima Y, Goto M, Okuzawa A, Sakamoto K (2015) Treatment of internal hemorrhoids by endoscopic sclerotherapy with aluminum potassium sulfate and tannic acid. Diagn Ther Endosc 2015:517690

    Article  PubMed  PubMed Central  Google Scholar 

  • Trompetto M, Clerico G, Cocorullo GF, Giordano P, Marino F, Martellucci J, Milito G, Mistrangelo M, Ratto C (2015) Evaluation and management of hemorrhoids: Italian society of colorectal surgery (SICCR) consensus statement. Tech Coloproctol 19:567–575. [Erratum in: Tech Coloproctol (2016) 20:201]

    Article  CAS  PubMed  Google Scholar 

  • Trowers EA, Ganga U, Rizk R, Ojo E, Hodges D (1998) Endoscopic hemorrhoidal ligation: preliminary clinical experience. Gastrointest Endosc 48:49–52

    Article  CAS  PubMed  Google Scholar 

  • Wald A, Bharucha AE, Cosman BC, Whitehead WE (2014) ACG clinical guideline: management of benign anorectal disorders. Am J Gastroenterol 109:1141–1157

    Article  PubMed  Google Scholar 

  • Walker AJ, Leicester RJ, Nicholls RJ, Mann CV (1990) A prospective study of infrared coagulation, injection and rubber band ligation in the treatment of hemorrhoids. Int J Colorect Dis 199:113–116

    Article  Google Scholar 

  • Wehermann T, Riphaus A, Feinstein J, Stergiou N (2004) Hemorrhoidal elastic band ligation with flexible videoendoscopes: a prospective, randomized comparison with the conventional technique that uses rigid proctoscope. Gastrointest Endosc 60:191–195

    Article  Google Scholar 

  • Yano T, Yano K (2015) Comparison of injection sclerotherapy between 5% phenol in almond oil and aluminum potassium sulfate and tannic acid for grade 3 hemorrhoids. Ann Coloproctol 31:103–105

    Article  PubMed  PubMed Central  Google Scholar 

  • Yano T, Nogaki T, Asano M, Tanaka S, Kawakami K, Matsuda Y (2013) Outcomes of case-matched injection sclerotherapy with a new agent for hemorrhoids in patients treated with or without blood thinners. Surg Today 43:854–858

    Article  CAS  PubMed  Google Scholar 

  • Yeomans FC (1931) Injection treatment of hemorrhoids. Am J Surg 14:489–491

    Article  Google Scholar 

  • Zhang T, Xu LJ, Xiang J, He Z, Peng ZY, Huang GM, Ji GZ, Zhang FM (2015) Cap-assisted endoscopic sclerotherapy for hemorrhoids: methods, feasibility and efficacy. World J Gastrointest Endosc 7:1334–1340

    Article  PubMed  PubMed Central  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Alessandra Bizzotto .

Editor information

Editors and Affiliations

1 Supplementary Electronic Material (S)

(MPG 127000 kb)

Rights and permissions

Reprints and permissions

Copyright information

© 2018 Springer International Publishing AG, part of Springer Nature

About this entry

Check for updates. Verify currency and authenticity via CrossMark

Cite this entry

Bizzotto, A., Codazzi, M., Spada, C. (2018). Endoscopic Treatment of Internal Hemorrhoids. In: Ratto, C., Parello, A., Litta, F. (eds) Hemorrhoids. Coloproctology, vol 2. Springer, Cham. https://doi.org/10.1007/978-3-319-53357-5_7

Download citation

  • DOI: https://doi.org/10.1007/978-3-319-53357-5_7

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-53356-8

  • Online ISBN: 978-3-319-53357-5

  • eBook Packages: MedicineReference Module Medicine

Publish with us

Policies and ethics