Abstract
Interbody cages represent an invaluable technologic advancement in the field of spinal fusion surgery, particularly anterior cervical discectomy and fusion (ACDF). Interbody cages improve sagittal alignment, aid in fusion by allowing for containment of graft material, and restore biomechanical stability after discectomy. Various design iterations and materials have been used over the last two to three decades, and advancements in materials science and cage properties have provided improved functional utility of interbody cages in ACDF surgery. This chapter provides an overview of the history of cervical interbody cages, including improvements in design, material, and methods of manufacturing processes of cervical interbody cages that have yielded the designs most commonly utilized today.
References
An HS, Simpson JM, Glover JM et al (1995) Comparison between allograft plus demineralized bone matrix versus autograft in anterior cervical fusion. Spine 20:2211–2216
Bagby G (1988) Arthrodesis by the distraction-compression method using a stainless steel implant. Orthopedics 11(6):931–934
Bent MJ, Oosting J, Wouda EJ et al (1996) Anterior cervical discectomy with or without fusion with acrylate. Spine 21:834–840
Bishop RC, Moore KA, Hadley MN (1996) Anterior cervical interbody fusion using autogeneic and allogeneic bone graft substrate: a prospective comparative analysis. J Neurosurg 85:206–210
Brown MD, Malinin TI, Davis PB (1976) A roentgenographic evaluation of frozen allografts versus autografts in anterior cervical spine fusions. Clin Orthop 119:231–236
Chong E, Pelletier MH, Mobbs RJ, Walsh WR (2015) The design evolution of interbody cages in anterior cervical discectomy and fusion: a systematic review. BMC Musculoskelet Disord 16:99. https://doi.org/10.1186/s12891-015-0546-x
DeBowes RM, Grant BD, Bagby GW et al (1984) Cervical vertebral interbody fusion in the horse: a comparative study of bovine xenografts and autografts supported by stainless steel baskets. Am J Vet Res 45:191–199
Ibanez J, Carreno A, Garcia-Amorena C et al (1998) Results of the biocompatible osteoconductive polymer (BOP) as an intersomatic graft in anterior cervical surgery. Acta Neuroshir (Wien) 140:126–133
McConnell JR, Freeman BJ, Debnath UK, Grevitt MP, Prince HG, Webb JK (2003) A prospective randomized comparison of coralline hydroxyapatite with autograft in cervical interbody fusion. Spine 28(4):317–323
Cage Design References
An HS, Simpson JM, Glover JM, Stephany J (1995) Comparison between allograft plus demineralized bone matrix versus autograft in anterior cervical fusion|a prospective multicenter study. Spine 20(Suppl):2211–2216
Banco SP, Jenis L, Tromanhauser S, Rand F, Banco RJ (2002) The use of cervical cages for treatment of cervical disc disease. Curr Opin Orthop 13(3):220–223
Cauthen JC, Kinard RE, Vogler JB, Jackson DE, DePaz OB, Hunter OL, Wasserburger LB, Williams VM (1998) Outcome analysis of noninstrumented anterior cervical discectomy and interbody fusion in 348 patients. Spine 23(2):188–192
Chen Y, Chen D, Guo Y, Wang X, Lu X, He Z, Yuan W (2008) Subsidence of titanium mesh cage: a study based on 300 cases. J Spinal Disord Tech 21(7):489–492
Chong E, Pelletier MH, Mobbs RJ, Walsh WR (2015) The design evolution of interbody cages in anterior cervical discectomy and fusion: a systematic review. BMC Musculoskelet Disord 16(1):99
Epari DR, Kandziora F, Duda GN (2005) Stress shielding in box and cylinder cervical interbody fusion cage designs. Spine 30(8):908–914
Gödde S, Fritsch E, Dienst M, Kohn D (2003) Influence of cage geometry on sagittal alignment in instrumented posterior lumbar Interbody fusion. Spine 28(15):1693–1699
Hacker RJ (2002) Threaded cages for degenerative cervical disease. Clin Orthop Relat Res 394:39–46
Jain S, Eltorai AEM, Ruttiman R, Daniels AH (2016) Advances in spinal Interbody cages. Orthop Surg 8(3):278–284
Kaiser MG, Haid RW Jr, Subach BR, Barnes B, Rodts GE Jr (2002) Anterior cervical plating enhances arthrodesis after discectomy and fusion with cortical allograft. Neurosurgery 50(2):229–236; discussion 236–8
Kandziora F, Pflugmacher R, Schäfer J, Born C, Duda G, Haas NP, Mittlmeier T (2001) Biomechanical comparison of cervical spine interbody fusion cages. Spine 26(17):1850–1857
Kandziora F, Schollmeier G, Scholz M, Schaefer J, Scholz A, Schmidmaier G, Schröder R, Bail H, Duda G, Mittlmeier T, Haas NP (2002) Influence of cage design on interbody fusion in a sheep cervical spine model. J Neurosurg Spine 96(3):321–332
Kast E, Derakhshani S, Bothmann M, Oberle J (2008) Subsidence after anterior cervical inter-body fusion. A randomized prospective clinical trial. Neurosurg Rev 32(2):207–214
Keogh A, Hardcastle P, Ali SF (2008) Anterior cervical fusion using the IntExt combined cage/plate. J Orthop Surg 16(1):3–8
Kettler A, Wilke H-J, Claes L (2001) Effects of neck movements on stability and subsidence in cervical interbody fusion: an in vitro study. J Neurosurg Spine 94(1):97–107
Kozak JA, OʼBrien JP (1990) Simultaneous combined anterior and posterior fusion, an independent analysis of a treatment for the disabled low-back pain patient. Spine 15(4):322–328
Kulkarni AG, Hee HT, Wong HK (2007) Solis cage (PEEK) for anterior cervical fusion: preliminary radiological results with emphasis on fusion and subsidence. Spine J 7(2):205–209
Matgé G (2002) Cervical cage fusion with 5 different implants: 250 cases. Acta Neurochir 144(6):539–549. discussion 550
McConnell JR, Freeman BJC, Debnath UK, Grevitt MP, Prince HG, Webb JK (2003) A prospective randomized comparison of coralline hydroxyapatite with autograft in cervical interbody fusion. Spine 28(4):317–323
Ono K, Ebara S, Yonenobu K, Hosono N, Dunn EJ (1992) Prosthetic replacement surgery for spine metastasis. In: Recent advances in musculoskeletal oncology. Springer Japan, Tokyo, pp 208–218
Pisano AJ, Short TK, Formby PM, Helgeson MD (2016) Anterior cervical discectomy and fusion techniques: bone graft, biologics, interbody spacers, and plating options. Semin Spine Surg 28(2):84–89
Samandouras G, Shafafy M, Hamlyn PJ (2001) A new anterior cervical instrumentation system combining an intradiscal cage with an integrated plate: an early technical report. Spine 26(10):1188–1192
Shimamoto N, Cunningham BW, Dmitriev AE, Minami A, McAfee PC (2001) Biomechanical evaluation of stand-alone interbody fusion cages in the cervical spine. Spine 26(19):E432–E436
Smith GW, Robinson RA (1958) The treatment of certain cervical-spine disorders by anterior removal of the intervertebral disc and interbody fusion. J Bone Joint Surg 40(3):607–624
Steffen T, Tsantrizos A, Aebi M (2000) Effect of implant design and endplate preparation on the compressive strength of interbody fusion constructs. Spine 25(9):1077–1084
Truumees E (2011) Cervical instrumentation. In: Rothman Simeone the spine. Elsevier, Philadelphia, pp 1175–1218
van Dijk M, Smit TH, Sugihara S, Burger EH, Wuisman PI (2002) The effect of cage stiffness on the rate of lumbar Interbody fusion. Spine 27(7):682–688
Weiner BK, Fraser RD (1998) Spine update lumbar interbody cages. Spine 23(5):634–640
Wilke HJ, Kettler A, Claes L (2000) Primary stabilizing effect of interbody fusion devices for the cervical spine: an in vitro comparison between three different cage types and bone cement. Eur Spine J 9(5):410–416
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Richards, J., Fredericks, D.R., Slaven, S.E., Wagner, S.C. (2021). Interbody Cages: Cervical. In: Cheng, B.C. (eds) Handbook of Spine Technology. Springer, Cham. https://doi.org/10.1007/978-3-319-44424-6_62
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DOI: https://doi.org/10.1007/978-3-319-44424-6_62
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