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Endovascular Technologies for Chronic Critical Limb Ischemia

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Critical Limb Ischemia

Abstract

Endovascular interventions for symptomatic peripheral artery disease (PAD) have undergone significant progress in recent years. Trials, however, remain limited for evaluating the efficacy and safety of these technologies in critical limb ischemia (CLI). This chapter attempts to review the mechanism of restenosis which has provided the impetus for the development of multiple endovascular options for PAD interventions. Following it is a review of available evidence for the use of percutaneous transluminal angioplasty (PTA), stent technologies including bare-metal (BMS), bare-nitinol, and drug-eluting stents (DES); cryoplasty; cutting and scoring balloons; and drug-eluting balloon (DEB) technologies. Finally, adjunctive technologies designed for intervention in special circumstances are reviewed including atherectomy technologies, technologies for intervening on chronic total occlusions (CTOs), and embolic protection devices.

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Panico, A.F., Jafferani, A., Johnson, P.A., Lopez, J.J., Laird, J.R., Dieter, R.S. (2017). Endovascular Technologies for Chronic Critical Limb Ischemia. In: Dieter, R., Dieter, Jr, R., Dieter, III, R., Nanjundappa, A. (eds) Critical Limb Ischemia. Springer, Cham. https://doi.org/10.1007/978-3-319-31991-9_35

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