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Cortical Dysplasia

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Textbook of Pediatric Neurosurgery

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Abstract

The most common etiologic factor requiring epilepsy surgery in children is cortical dysplasia (CD). In recent years, the advent of modern imaging techniques and refined surgical approaches has allowed for a greater number of these patients to be properly diagnosed and treated, providing very good seizure outcomes. New pathological classifications of the different types of malformations of cortical development (MCD), CD among them, have included embryological, radiological, and genetic features. Moreover, it is now well recognized that the key to successful surgical treatment is to carry out a comprehensive presurgical workup, which consists of various noninvasive assessments, but that might also require invasive techniques such as the use of subdural electrodes or stereoelectroencephalography (SEEG). Thereby, completeness of resection of CD, which is certainly the most important prognostic factor for seizure freedom, can be achieved by means of different surgical strategies. These clinical, pathological, diagnostic, and surgical aspects, as well as outcome and other details regarding CD in children, will be discussed herein.

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Authors and Affiliations

  1. Division of Pediatric Neurosurgery and Pediatric Epilepsy Surgery, Ribeirão Preto Medical School – University of São Paulo, Campus Universitario, 14049-900, Ribeirão Preto, São Paulo, Brazil

    Helio Rubens Machado & Marcelo Volpon Santos

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  1. Helio Rubens Machado
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  2. Marcelo Volpon Santos
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Correspondence to Helio Rubens Machado .

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Editors and Affiliations

  1. International Neuroscience Institute, Hannover, Germany

    Concezio Di Rocco

  2. Oakland Medical Center, Oakland, California, USA

    Dachling Pang

  3. University of Toronto Hospital for Sick Children, Toronto, Ontario, Canada

    James T. Rutka

Section Editor information

  1. Director of Pediatric Neurosurgery, International Neuroscience Institute, Hannover, Germany

    Concezio Di Rocco

  2. Pediatric Neurosurgery, Institute of Neurosurgery, Catholic University Medical School, Largo “A. Gemelli”,8, 00168, Rome, Italy

    Gianpiero Tamburrini

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Machado, H.R., Santos, M.V. (2017). Cortical Dysplasia. In: Di Rocco, C., Pang, D., Rutka, J. (eds) Textbook of Pediatric Neurosurgery. Springer, Cham. https://doi.org/10.1007/978-3-319-31512-6_41-1

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  • DOI: https://doi.org/10.1007/978-3-319-31512-6_41-1

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