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Roles of Probiotics on Lifelong Diversifications of Gut Microbiota

  • Chapter
Beneficial Microorganisms in Food and Nutraceuticals

Part of the book series: Microbiology Monographs ((MICROMONO,volume 27))

  • 2012 Accesses

Abstract

A diverse community of microbiota has been proven to inhabit the gastrointestinal tract along its length. This indigenous gut microbiota is important to the host metabolism and health. Although it is widely recognized that the initial contact with mothers during delivery shapes the composition of gut microbiota in newborns, uncertainties arising throughout the human life such as development of disorders, diseases, and stressful experiences may twist the microbial balance in host. These subsequently lead to the occurrence of aberrant composition of gut microbiota which often favors the proliferation of pathogenic bacteria. While alteration of gut microbiota composition has been suggested to be one of the contributing factors to pathogenesis of diseases, an enormous interest has emerged in the reestablishment of microbial balance in gut via the intervention of probiotics. In this chapter, we provide some evidence on numerous factors that affect the compositions gut microbiota, beginning from infancy to adulthood, and the effectiveness of probiotic therapy in tackling health issues arising from such alterations.

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Acknowledgment

This work was supported by the FRGS grant (203/PTEKIND/6711372) and MyBrain scholarship provided by the Ministry of Higher Education Malaysia and the USM IReC grant (1002/PTEKIND/910406) provided by Universiti Sains Malaysia.

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Authors and Affiliations

  1. Bioprocess Technology Division, School of Industrial Technology, Universiti Sains Malaysia, 11800, Penang, Malaysia

    Yung-Sheng Loh, Lee-Ching Lew & Min-Tze Liong

  2. Institute for Research in Molecular Medicine, Universiti Sains Malaysia, 11800, Penang, Malaysia

    Boon-Yin Khoo

  3. Advanced Medical and Dental Institute, Universiti Sains Malaysia, 11800, Penang, Malaysia

    Nor Azlina Khalil

  4. Centre for Advanced Analytical Toxicology Services, Universiti Sains Malaysia, 11800, Penang, Malaysia

    Chee-Yuen Gan

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    Min-Tze Liong

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Loh, YS., Lew, LC., Khoo, BY., Khalil, N.A., Gan, CY., Liong, MT. (2015). Roles of Probiotics on Lifelong Diversifications of Gut Microbiota. In: Liong, MT. (eds) Beneficial Microorganisms in Food and Nutraceuticals. Microbiology Monographs, vol 27. Springer, Cham. https://doi.org/10.1007/978-3-319-23177-8_11

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