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Gold-Based Nanomaterials for Applications in Nanomedicine

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Light-Responsive Nanostructured Systems for Applications in Nanomedicine

Part of the book series: Topics in Current Chemistry ((TOPCURRCHEM,volume 370))

Abstract

In this review, an overview of the current state-of-the-art of gold-based nanomaterials (Au NPs) in medical applications is given. The unique properties of Au NPs, such as their tunable size, shape, and surface characteristics, optical properties, biocompatibility, low cytotoxicity, high stability, and multifunctionality potential, among others, make them highly attractive in many aspects of medicine. First, the preparation methods for various Au NPs including functionalization strategies for selective targeting are summarized. Second, recent progresses on their applications, ranging from the diagnostics to therapeutics are highlighted. Finally, the rapidly growing and promising field of gold-based theranostic nano-platforms is discussed. Considering the great body of existing information and the high speed of its renewal, we chose in this review to generalize the data that have been accumulated during the past few years for the most promising directions in the use of Au NPs in current medical research.

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Acknowledgments

This work was supported by the European Commission (project Futurenanoneeds to WJP). SA, BP, and CCC acknowledge the Alexander von Humboldt Foundation for a PostDoc fellowship. QZ acknowledges CSC for funding. MGS acknowledges the Youssef Jameel Foundation for a PhD fellowship. AE acknowledges Junta de Andalucia for a Talentia Postdoc Fellowship, co-financed by the European Union’s Seventh Framework Programme, grant agreement no 267226. MC acknowledges a Research Fellow Grant from Ikerbasque, Basque Foundation for Science.

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Authors and Affiliations

  1. Fachbereich Physik, Philipps Universität Marburg, 35037, Marburg, Germany

    Sumaira Ashraf, Beatriz Pelaz, Alberto Escudero, Wolfgang J. Parak, Mahmoud G. Soliman, Qian Zhang & Carolina Carrillo-Carrion

  2. CIC biomaGUNE, San Sebastian, Spain

    Pablo del Pino, Mónica Carril & Wolfgang J. Parak

  3. Ikerbasque, Basque Foundation for Science, 48011, Bilbao, Spain

    Mónica Carril

  4. Instituto de Ciencia de Materiales de Sevilla, CSIC-University of Seville, 41092, Seville, Spain

    Alberto Escudero

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  1. Sumaira Ashraf
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  1. University of Catania, Catania, Italy

    Salvatore Sortino

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Ashraf, S. et al. (2016). Gold-Based Nanomaterials for Applications in Nanomedicine. In: Sortino, S. (eds) Light-Responsive Nanostructured Systems for Applications in Nanomedicine. Topics in Current Chemistry, vol 370. Springer, Cham. https://doi.org/10.1007/978-3-319-22942-3_6

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