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Causes of Short Bowel Syndrome in Adults

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Contemporary Small Bowel Transplantation

Part of the book series: Organ and Tissue Transplantation ((OTT))

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Abstract

In adults, short bowel syndrome results from a large number of etiologies, many of which will be discussed within this chapter. Short bowel syndrome can result from Crohn’s disease, acute mesenteric ischemia, various forms of trauma, obstruction, and lastly, postoperatively. Crohn’s disease leads to short bowel syndrome through the disease itself and the necessity of surgeries to mediate the intestinal damage. Acute mesenteric ischemia causes short bowel syndrome through reduction of blood flow but is not frequently observed. Similarly, trauma, such as blunt and penetrating trauma, can directly lead to short bowel syndrome through the damage of the gastrointestinal tract and organs in the abdomen. Obstruction, whether congenital, acquired, iatrogenic, etc., can contribute to progression to short bowel syndrome. With respect to obstruction, hernias in various locations, volvuli at different locations along the gastrointestinal tract, luminal obstructions possibly resulting from malignancy, and radiation-induced injury will be specifically addressed. Postoperatively, surgery in itself can place a patient at high risk for development of short bowel syndrome.

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Author information

Authors and Affiliations

  1. The Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA, USA

    Gary A. Lindenbaum, Joshua A. Marks & Stephanie A. Costa

  2. Rush Medical College, Rush University, Chicago, IL, USA

    Thea P. Price

  3. Division of Traumatology, Surgical Critical Care and Emergency Surgery, Department of Surgery, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA

    Joshua A. Marks

Authors
  1. Gary A. Lindenbaum
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  2. Joshua A. Marks
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  3. Thea P. Price
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  4. Stephanie A. Costa
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Corresponding author

Correspondence to Gary A. Lindenbaum .

Editor information

Editors and Affiliations

  1. Division of Transplantation, Thomas Jefferson University Department of Surgery, Philadelphia, Pennsylvania, USA

    Ashesh Piyush Shah

  2. Division of Transplantation, Thomas Jefferson University Hospital Jefferson Medical College, Philadelphia, Pennsylvania, USA

    Cataldo Doria

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Lindenbaum, G.A., Marks, J.A., Price, T.P., Costa, S.A. (2018). Causes of Short Bowel Syndrome in Adults. In: Shah, A., Doria, C. (eds) Contemporary Small Bowel Transplantation. Organ and Tissue Transplantation. Springer, Cham. https://doi.org/10.1007/978-3-319-05547-3_24-1

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  • DOI: https://doi.org/10.1007/978-3-319-05547-3_24-1

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-05547-3

  • Online ISBN: 978-3-319-05547-3

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