Abstract
Various techniques are used to determine cutaneous blood flow, such as radioactive microspheres, xenon clearances, plethysmography, laser Doppler velocimetry (Flagrell 1986; Guy et al. 1985), and reflectance spectrophotometry (Kimura et al. 1988; Kakizoe et al. 1992).
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References and Further Reading
General Considerations
Flagrell B (1986) Clinical studies of skin microcirculation. Klin Wochenschr 64:943–946
Guy RH, Tur E, Maibach H (1985) Optical techniques for monitoring cutaneous microcirculation. Int J Dermatol 24:88–94
Kakizoe E, Kobayashi Y, Shimoura K, Hattori K, Jidoi J (1992) Real-time measurement of microcirculation of skin by reflectance spectrophotometry. J Pharmacol Toxicol Methods 28:175–180
Kimura T, Tsushima N, Nakayama R, Yoshizaki S, Otsiji K, Shinohara M (1988) Effects of prostaglandin E1 on the microcirculation of skin in the arteriosclerosis obliterans. J Jpn Coll Angiol 28:177–181
Laser Doppler Velocimetry
Guy RH, Tur E, Maibach H (1985) Optical techniques for monitoring cutaneous microcirculation. Int J Dermatol 24:88–94
Hirkaler GM, Rosenberger LB (1989) Simultaneous two-probe laser Doppler velocimetric assessment of topically applied drugs in rats. J Pharmacol Methods 21:123–127
Knight KR, Collopy PA, O’Brien BM (1987) Correlation of viability and laser Doppler flowmetry in ischemic flaps. J Surg Res 43:444–451
Measurement of Skin Microcirculation by Reflectance Spectroscopy
Da Costa R, Aggarwal SJ, Diller KR, Baxter CR (1992) The effects of epinephrine, ibuprofen, and tetrachlorodecaoxide on cutaneous microcirculation in thermally injured hamsters. J Burn Care Rehabil 13:396–402
Hertel RF (1986) Microcirculatory measurements in the same conscious rats (WKY and SHR) during the first year from birth. Microcirc Endothelium Lymphatics 3:75–87
Hertel RF (1992) Potassium channel activation improves blood flow pattern of conscious rats in cutaneous microcirculation. Clin Exp Pharmacol Physiol 19:243–248
Kakizoe E, Kobayashi Y, Shimoura K, Hattori K, Jidoi J (1992) Real-time measurement of microcirculation of skin by reflectance spectrophotometry. J Pharmacol Toxicol Methods 28:175–180
Kimura T, Tsushima N, Nakayama R, Yoshizaki S, Otsiji K, Shinohara M (1988) Effects of prostaglandin E1 on the microcirculation of skin in the arteriosclerosis obliterans. J Jpn Coll Angiol 28:177–181
Tyml K, Ellis CG (1982) Evaluation of the flying spot technique as a television method for measuring red cell velocity in microvessels. Int J Microcirc Clin Exp 11:145–155
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Maibach, H. (2016). Cutaneous Microcirculation. In: Hock, F. (eds) Drug Discovery and Evaluation: Pharmacological Assays. Springer, Cham. https://doi.org/10.1007/978-3-319-05392-9_111
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DOI: https://doi.org/10.1007/978-3-319-05392-9_111
Publisher Name: Springer, Cham
Print ISBN: 978-3-319-05391-2
Online ISBN: 978-3-319-05392-9
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