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Endoscopic Duodeno-Jejunal Bypass Sleeve Treatment for Obesity

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Obesity, Bariatric and Metabolic Surgery

Abstract

Bariatric surgery has experienced a dramatic evolution over the last years. The search for less invasive procedures to improve the benefit/risk ratio and to expand the benefits of these interventions to a larger group of patients has led to the development of primary endoscopic procedures for the treatment of obesity and its associated diseases. The duodenal-jejunal bypass liner (DJBL) is a highly flexible and impermeable tube that can be endoscopically implanted and explanted. It is specifically designed to create a duodenal-jejunal exclusion. The DJBL treatment has now become a primary intervention for the treatment of morbid obesity and to improve glycemic control in obese patients with type 2 diabetes mellitus (T2DM). Available evidence supports the role of DJBL in treating obesity and improving glycemic control in a significant proportion of severely obese diabetic patients. Early removal and a higher rate of serious adverse events in clinical practice are the most important limitations in terms of safety. Randomized clinical trials are needed to evaluate the safety/efficacy ratio of the procedure and its clinical use in future.

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Author information

Authors and Affiliations

  1. Department of Digestive Surgery, Pontificia Universidad Católica de Chile, Santiago, Chile

    Rodrigo Muñoz MD, PhD

  2. Department of Surgery, Faculty of Medicine, Universidad de los Andes, Santiago, Chile

    Alex Escalona MD

Authors
  1. Rodrigo Muñoz MD, PhD
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  2. Alex Escalona MD
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Corresponding author

Correspondence to Alex Escalona MD .

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Editors and Affiliations

  1. Homerton University Hospital, London, United Kingdom

    Sanjay Agrawal

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Endoscopic Duodenal-Jejunal Bypass Liner Treatment (MOV 993349 kb)

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Muñoz, R., Escalona, A. (2016). Endoscopic Duodeno-Jejunal Bypass Sleeve Treatment for Obesity. In: Agrawal, S. (eds) Obesity, Bariatric and Metabolic Surgery. Springer, Cham. https://doi.org/10.1007/978-3-319-04343-2_51

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  • DOI: https://doi.org/10.1007/978-3-319-04343-2_51

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-04342-5

  • Online ISBN: 978-3-319-04343-2

  • eBook Packages: MedicineMedicine (R0)

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