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Abstract

Mechanical ventilatory support (MV) management of critically ill patients has undergone profound changes over the past 10 years. This practice has evolved from deep-sedation associated to a totally controlled ventilation for prolonged periods of time to minimal sedation with daily interruptions and the corollary use of ventilatory modes based on spontaneous breathing. By reducing the depth and the duration of the sedation, invasive mechanical ventilation in intensive care units (ICUs) has been significantly shortened. The benefit of such strategies is now clearly demonstrated [1–3] and could be further increased by the use of automated weaning modes such as ASV, Intellivent and Smartcare. These promising automatic modes demonstrated their safety in managing ventilation and weaning even proving a reduction in weaning time especially when the patient-to-nurse ratio is high. Clear benefit for survival is still needed, and accceptance by health-care teams remains a challenge.

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References

  1. Hess DR, MacIntyre NR. Ventilator discontinuation: why are we still weaning? Am J Respir Crit Care Med. 2011;184(4):392–4.

    Article  PubMed  Google Scholar 

  2. Epstein SK. Weaning from mechanical ventilation. Respir Care. 2002;47(4):454–66; discussion 66–8.

    PubMed  Google Scholar 

  3. Girard TD, Kress JP, Fuchs BD, Thomason JW, Schweickert WD, Pun BT, et al. Efficacy and safety of a paired sedation and ventilator weaning protocol for mechanically ventilated patients in intensive care (Awakening and Breathing Controlled trial): a randomised controlled trial. Lancet. 2008;371(9607):126–34.

    Article  PubMed  Google Scholar 

  4. MacIntyre NR, Cook DJ, Ely Jr EW, Epstein SK, Fink JB, Heffner JE, et al. Evidence-based guidelines for weaning and discontinuing ventilatory support: a collective task force facilitated by the American College of Chest Physicians; the American Association for Respiratory Care; and the American College of Critical Care Medicine. Chest. 2001;120(6 Suppl):375S–95.

    Article  PubMed  CAS  Google Scholar 

  5. Kollef MH, Shapiro SD, Silver P, St John RE, Prentice D, Sauer S, et al. A randomized, controlled trial of protocol-directed versus physician-directed weaning from mechanical ventilation. Crit Care Med. 1997;25(4):567–74.

    Article  PubMed  CAS  Google Scholar 

  6. Esteban A, Alia I, Tobin MJ, Gil A, Gordo F, Vallverdu I, et al. Effect of spontaneous breathing trial duration on outcome of attempts to discontinue mechanical ventilation. Spanish Lung Failure Collaborative Group. Am J Respir Crit Care Med. 1999;159(2):512–8.

    Article  PubMed  CAS  Google Scholar 

  7. Cox CE, Carson SS, Govert JA, Chelluri L, Sanders GD. An economic evaluation of prolonged mechanical ventilation. Crit Care Med. 2007;35(8):1918–27.

    Article  PubMed  PubMed Central  Google Scholar 

  8. Needham DM, Bronskill SE, Calinawan JR, Sibbald WJ, Pronovost PJ, Laupacis A. Projected incidence of mechanical ventilation in Ontario to 2026: preparing for the aging baby boomers. Crit Care Med. 2005;33(3):574–9.

    Article  PubMed  Google Scholar 

  9. Zilberberg MD, de Wit M, Pirone JR, Shorr AF. Growth in adult prolonged acute mechanical ventilation: implications for healthcare delivery. Crit Care Med. 2008;36(5):1451–5.

    Article  PubMed  Google Scholar 

  10. Donchin Y, Seagull FJ. The hostile environment of the intensive care unit. Curr Opin Crit Care. 2002;8(4):316–20.

    Article  PubMed  Google Scholar 

  11. Scott LD, Rogers AE, Hwang WT, Zhang Y. Effects of critical care nurses’ work hours on vigilance and patients’ safety. Am J Crit Care. 2006;15(1):30–7.

    PubMed  Google Scholar 

  12. Le Gall JR, Azoulay E, Embriaco N, Poncet MC, Pochard F. [Burn out syndrome among critical care workers]. Bull Acad Natl Med. 2011;195(2):389–97; discussion 97–8.

    PubMed  Google Scholar 

  13. Scott LD, Hwang WT, Rogers AE. The impact of multiple care giving roles on fatigue, stress, and work performance among hospital staff nurses. J Nurs Adm. 2006;36(2):86–95.

    Article  PubMed  Google Scholar 

  14. McGlynn EA, Asch SM, Adams J, Keesey J, Hicks J, DeCristofaro A, et al. The quality of health care delivered to adults in the United States. N Engl J Med. 2003;348(26):2635–45.

    Article  PubMed  Google Scholar 

  15. Pronovost PJ, Rinke ML, Emery K, Dennison C, Blackledge C, Berenholtz SM. Interventions to reduce mortality among patients treated in intensive care units. J Crit Care. 2004;19(3):158–64.

    Article  PubMed  Google Scholar 

  16. Lellouche F, Brochard L. Advanced closed loops during mechanical ventilation (PAV, NAVA, ASV, SmartCare). Best Pract Res Clin Anaesthesiol. 2009;23(1):81–93.

    Article  PubMed  Google Scholar 

  17. Laubscher TP, Frutiger A, Fanconi S, Jutzi H, Brunner JX. Automatic selection of tidal volume, respiratory frequency and minute ventilation in intubated ICU patients as start up procedure for closed-loop controlled ventilation. Int J Clin Monit Comput. 1994;11(1):19–30.

    Article  PubMed  CAS  Google Scholar 

  18. Campbell RS, Branson RD, Johannigman JA. Adaptive support ventilation. Respir Care Clin N Am. 2001;7(3):425–40.

    Article  PubMed  CAS  Google Scholar 

  19. Otis AB, Fenn WO, Rahn H. Mechanics of breathing in man. J Appl Physiol. 1950;2(11):592–607.

    PubMed  CAS  Google Scholar 

  20. Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome. The Acute Respiratory Distress Syndrome Network. N Engl J Med. 2000;342(18):1301–8.

    Google Scholar 

  21. Brower RG, Lanken PN, MacIntyre N, Matthay MA, Morris A, Ancukiewicz M, et al. Higher versus lower positive end-expiratory pressures in patients with the acute respiratory distress syndrome. N Engl J Med. 2004;351(4):327–36.

    Article  PubMed  Google Scholar 

  22. Cannesson M, Attof Y, Rosamel P, Desebbe O, Joseph P, Metton O, et al. Respiratory variations in pulse oximetry plethysmographic waveform amplitude to predict fluid responsiveness in the operating room. Anesthesiology. 2007;106(6):1105–11.

    Article  PubMed  Google Scholar 

  23. Sulzer CF, Chiolero R, Chassot PG, Mueller XM, Revelly JP. Adaptive support ventilation for fast tracheal extubation after cardiac surgery: a randomized controlled study. Anesthesiology. 2001;95(6):1339–45.

    Article  PubMed  CAS  Google Scholar 

  24. Gruber PC, Gomersall CD, Leung P, Joynt GM, Ng SK, Ho KM, et al. Randomized controlled trial comparing adaptive-support ventilation with pressure-regulated volume-controlled ventilation with automode in weaning patients after cardiac surgery. Anesthesiology. 2008;109(1):81–7.

    Article  PubMed  Google Scholar 

  25. Chen CW, Wu CP, Dai YL, Perng WC, Chian CF, Su WL, et al. Effects of implementing adaptive support ventilation in a medical intensive care unit. Respir Care. 2011;56(7):976–83.

    Article  PubMed  Google Scholar 

  26. Kirakli C, Ozdemir I, Ucar ZZ, Cimen P, Kepil S, Ozkan SA. Adaptive support ventilation for faster weaning in COPD: a randomised controlled trial. Eur Respir J. 2011;38(4):774–80.

    Article  PubMed  CAS  Google Scholar 

  27. Lellouche F, Mancebo J, Jolliet P, Roeseler J, Schortgen F, Dojat M, et al. A multicenter randomized trial of computer-driven protocolized weaning from mechanical ventilation. Am J Respir Crit Care Med. 2006;174(8):894–900.

    Article  PubMed  Google Scholar 

  28. Burns KE, Meade MO, Lessard MR, Hand L, Zhou Q, Keenan SP, et al. Wean earlier and automatically with New technology (the WEAN study): a multicentre, pilot randomized controlled trial. Am J Respir Crit Care Med. 2013;187(11):1203–11.

    Article  PubMed  Google Scholar 

  29. Rose L, Presneill JJ, Johnston L, Cade JF. A randomised, controlled trial of conventional versus automated weaning from mechanical ventilation using SmartCare/PS. Intensive Care Med. 2008;34(10):1788–95.

    Article  PubMed  Google Scholar 

  30. Schadler D, Engel C, Elke G, Pulletz S, Haake N, Frerichs I, et al. Automatic control of pressure support for ventilator weaning in surgical intensive care patients. Am J Respir Crit Care Med. 2012;185(6):637–44.

    Article  PubMed  Google Scholar 

  31. Lellouche F, Bouchard PA, Simard S, L’Her E, Wysocki M. Evaluation of fully automated ventilation: a randomized controlled study in post-cardiac surgery patients. Intensive Care Med. 2013;39(3):463–71.

    Article  PubMed  Google Scholar 

  32. Burns KE, Lellouche F, Nisenbaum R, Lessard MR, Friedrich JO. Automated weaning and SBT systems versus non-automated weaning strategies for weaning time in invasively ventilated critically ill adults. Cochrane Database Syst Rev. 2014;9, CD008638.

    PubMed  Google Scholar 

  33. Arnal JM, Wysocki M, Novotni D, Demory D, Lopez R, Donati S, et al. Safety and efficacy of a fully closed-loop control ventilation (IntelliVent-ASV(R)) in sedated ICU patients with acute respiratory failure: a prospective randomized crossover study. Intensive Care Med. 2012;38(5):781–7.

    Article  PubMed  Google Scholar 

  34. Clavieras N, Wysocki M, Coisel Y, Galia F, Conseil M, Chanques G, et al. Prospective randomized crossover study of a new closed-loop control system versus pressure support during weaning from mechanical ventilation. Anesthesiology. 2013;119(3):631–41.

    Article  PubMed  Google Scholar 

  35. Arnal JM, Garnero A, Novonti D, Demory D, Ducros L, Berric A, et al. Feasibility study on full closed-loop control ventilation (IntelliVent-ASV) in ICU patients with acute respiratory failure: a prospective observational comparative study. Crit Care. 2013;17(5):R196.

    Article  PubMed  PubMed Central  Google Scholar 

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Wallet, F., Ledochowski, S., Bernet, C., Mottard, N., Friggeri, A., Piriou, V. (2016). Automated Weaning Modes. In: Esquinas, A. (eds) Noninvasive Mechanical Ventilation and Difficult Weaning in Critical Care. Springer, Cham. https://doi.org/10.1007/978-3-319-04259-6_3

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  • DOI: https://doi.org/10.1007/978-3-319-04259-6_3

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