Abstract
Acute febrile neutrophilic dermatosis (Sweet’s Syndrome)
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![figure 1](http://media.springernature.com/lw685/springer-static/image/chp%3A10.1007%2F978-3-319-03218-4_111/MediaObjects/320127_1_En_111_Fig1_HTML.jpg)
Acute febrile neutrophilic dermatosis (Sweet’s Syndrome)
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Acute febrile neutrophilic dermatosis (Sweet’s Syndrome)
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A.
Upper respiratory infection or flu-like symptoms frequently precede the syndrome
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B.
Tender, edematous, erythematous papules and plaques that may develop vesicles, bullae, or pustules within the plaques
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C.
Vesiculobullous variant most frequently associated with acute myelogenous leukemia and may progress to ulceration resembling pyoderma gangrenosum
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D.
Favors the head, neck, and extremities (especially dorsal hand)
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E.
May be widespread in malignancy-associated cases
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F.
Pathergy is common
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G.
Resolves spontaneously in 5–12 weeks, recurs in 30 %
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H.
Associated conditions
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1.
Infections—upper respiratory tract infections due to streptococcus, Yersinia
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2.
Vaccinations
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3.
Malignancies
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a.
Hematologic (especially acute myelogenous leukemia), 10–20 %
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b.
Solid tumors
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a.
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4.
Inflammatory bowel disease
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5.
Autoimmune disease
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6.
Drugs
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7.
Pregnancy
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1.
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A.
![figure 2](http://media.springernature.com/lw685/springer-static/image/chp%3A10.1007%2F978-3-319-03218-4_111/MediaObjects/320127_1_En_111_Fig2_HTML.jpg)
Acute febrile neutrophilic dermatosis (Sweet’s Syndrome)
Photograph courtesy of SpringerImages Database, Springer Publishing Company
-
Acute febrile neutrophilic dermatosis (Sweet’s Syndrome)
-
A.
Tender, edematous, erythematous plaques
-
A.
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Gloster, H.M., Gebauer, L.E., Mistur, R.L. (2016). Acute Febrile Neutrophilic Dermatosis (Sweet’s Syndrome). In: Absolute Dermatology Review. Springer, Cham. https://doi.org/10.1007/978-3-319-03218-4_111
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DOI: https://doi.org/10.1007/978-3-319-03218-4_111
Publisher Name: Springer, Cham
Print ISBN: 978-3-319-03217-7
Online ISBN: 978-3-319-03218-4
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