Abstract
It is well-known that bone is one of the most commonly replaced organs worldwide after a blood transfusion and therefore, the development of different strategies is necessary for treating bone defects. Based on this concept, bone surgical problems have been solved. Thanks to biomaterials, which involve calcium phosphates/silicates, porous metals, bioactive glasses, glass–ceramics, and synthetic polymers. Notably, hydroxyapatite (HA) is one of the calcium phosphate family, which possesses marvelous ability to integrate with hard tissues without triggering foreign body reactions and consequently, save patients from the possible undesirable complications. It is meaningful to mention that in spite of the attractive applications of HA in medicine, it has other important applications in many fields like agriculture, chemistry, and the environment. This chapter briefly discusses the different bone grafting materials, and their defects, 3D bioprinting of scaffolds, the definition and types of biomaterials, host responses to biomaterials, different methods for producing HA, and the different properties and applications of HA. Noteworthy, one can say that the preparation of HA with certain characteristics is very complicated due to the potential production of toxic intermediary phases that may occur during the synthesis process. Meanwhile, further investigations and descriptions of the HA structure and fictionalization could be achieved with molecular modeling at different levels.
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Ibrahim, M., Youness, R.A., Taha, M.A. (2024). Overview of Some Production Routes for Hydroxyapatite and Its Applications. In: Ikhmayies, S.J. (eds) Advances in Minerals Research. Advances in Material Research and Technology. Springer, Cham. https://doi.org/10.1007/978-3-031-49175-7_6
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