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Embryology, Anatomy, and Variations of the Anterior Cerebral Artery

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Anatomy of Cranial Arteries, Embryology and Variants

Abstract

The anterior cerebral artery (ACA) is one of the most important arteries of the brain and in particular of the telencephalon [1, 2]. The ACA is also one of the most studied cerebral arteries since it is a common location for intracranial aneurysms [3]. During the species’ evolution, the ACA acquires its vascular territories with the development of the telencephalon in mammals; before this event, its role is limited to the vascularization of the olfactory system and in part of the diencephalon [4]. In this chapter, the normal anatomy and functions of the ACA will be reminded with special attention to its embryological development and to its known anatomical variations.

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References

  1. Gomes F, Dujovny M, Umansky F, Ausman JI, Diaz FG, Ray WJ, et al. Microsurgical anatomy of the recurrent artery of Heubner. J Neurosurg. 1984;60(1):130–9. https://doi.org/10.3171/jns.1984.60.1.0130.

    Article  PubMed  CAS  Google Scholar 

  2. Gomes FB, Dujovny M, Umansky F, Berman SK, Diaz FG, Ausman JI, et al. Microanatomy of the anterior cerebral artery. Surg Neurol. 1986;26(2):129–41. https://doi.org/10.1016/0090-3019(86)90365-4.

    Article  PubMed  CAS  Google Scholar 

  3. Tahir RA, Haider S, Kole M, Griffith B, Marin H. Anterior cerebral artery: variant anatomy and pathology. J Vasc Interv Neurol. 2019;10(3):16–22.

    PubMed  PubMed Central  Google Scholar 

  4. Abbie AA. The morphology of the fore-brain arteries, with especial reference to the evolution of the basal ganglia. J Anat. 1934;68(Pt 4):433–70.

    PubMed  PubMed Central  CAS  Google Scholar 

  5. Moffat DB. The embryology of the arteries of the brain. Ann R Coll Surg Engl. 1962;30:368–82.

    PubMed  PubMed Central  CAS  Google Scholar 

  6. Padget DH. The development of cranial arteries in the human embryo. Contrib Embryol Carneg Instn. 1948;212:205–62.

    Google Scholar 

  7. Rosner SS, Rhoton AL Jr, Ono M, Barry M. Microsurgical anatomy of the anterior perforating arteries. J Neurosurg. 1984;61(3):468–85. https://doi.org/10.3171/jns.1984.61.3.0468.

    Article  PubMed  CAS  Google Scholar 

  8. Perlmutter D, Rhoton AL Jr. Microsurgical anatomy of the anterior cerebral-anterior communicating-recurrent artery complex. J Neurosurg. 1976;45(3):259–72. https://doi.org/10.3171/jns.1976.45.3.0259.

    Article  PubMed  CAS  Google Scholar 

  9. Perlmutter D, Rhoton AL Jr. Microsurgical anatomy of the distal anterior cerebral artery. J Neurosurg. 1978;49(2):204–28. https://doi.org/10.3171/jns.1978.49.2.0204.

    Article  PubMed  CAS  Google Scholar 

  10. Yasargil MG. Microneurosurgery. New York: Thieme Medical Publisher; 1984.

    Google Scholar 

  11. Farnarier P, Michotey P, Moscow N, Salamon G. An anatomical and radiological study of the cortical branches of the anterior cerebral artery (author’s transl). Ann Radiol (Paris). 1977;20(2):203–21.

    PubMed  CAS  Google Scholar 

  12. Lasjaunias P, Bereinstein A, Ter Brugge KG. Surgical neuroangiography. Berlin: Springer edition; 2001.

    Google Scholar 

  13. Lasjaunias P, Moret J, Manelfe C, Theron J, Hasso T, Seeger J. Arterial anomalies at the base of the skull. Neuroradiology. 1977;13(5):267–72. https://doi.org/10.1007/bf00347072.

    Article  PubMed  CAS  Google Scholar 

  14. Fisher E. Die Lageabweichungen der vorderen Hirnarterie in Gefassbild. Zentralbl Neurochir. 1938;3:300–12.

    Google Scholar 

  15. Uchino A, Nomiyama K, Takase Y, Kudo S. Anterior cerebral artery variations detected by MR angiography. Neuroradiology. 2006;48(9):647–52. https://doi.org/10.1007/s00234-006-0110-3.

    Article  PubMed  Google Scholar 

  16. Aydin IH, Takci E, Kadioglu HH, Tuzun Y, Kayaoglu CR, Barlas E. Vascular variations associated with anterior communicating artery aneurysms-an intraoperative study. Minim Invasive Neurosurg. 1997;40(1):17–21. https://doi.org/10.1055/s-2008-1053407.

    Article  PubMed  CAS  Google Scholar 

  17. Rhoton AL Jr, Perlmutter D. Microsurgical anatomy of anterior communicating artery aneurysms. Neurol Res. 1980;2(3–4):217–51. https://doi.org/10.1080/01616412.1980.11739581.

    Article  PubMed  Google Scholar 

  18. Kaplan HA. The lateral perforating branches of the anterior and middle cerebral arteries. J Neurosurg. 1965;23(3):305–10. https://doi.org/10.3171/jns.1965.23.3.0305.

    Article  PubMed  CAS  Google Scholar 

  19. Marinkovic S, Milisavljevic M, Kovacevic M. Anatomical bases for surgical approach to the initial segment of the anterior cerebral artery. Microanatomy of Heubner’s artery and perforating branches of the anterior cerebral artery. Surg Radiol Anat. 1986;8(1):7–18.

    Article  PubMed  CAS  Google Scholar 

  20. Barry DM. Surgical treatment of anterior cerebral-anterior communicating artery aneurysms. R I Med J. 1972;55(8):245–7.

    PubMed  CAS  Google Scholar 

  21. Kaplan HA, Krieger AJ. Vascular anatomy of the preoptic region of the brain. Acta Neurochir. 1980;54(3–4):233–41. https://doi.org/10.1007/bf01407090.

    Article  PubMed  CAS  Google Scholar 

  22. Stefani MA, Schneider FL, Marrone AC, Severino AG, Jackowski AP, Wallace MC. Anatomic variations of anterior cerebral artery cortical branches. Clin Anat. 2000;13(4):231–6. https://doi.org/10.1002/1098-2353(2000)13:4<231::AID-CA1>3.0.CO;2-T.

    Article  PubMed  CAS  Google Scholar 

  23. Krishnamoorthy T, Gupta AK, Bhattacharya RN, Rajesh BJ, Purkayastha S. Anomalous origin of the callosomarginal artery from the A1 segment with an associated saccular aneurysm. AJNR Am J Neuroradiol. 2006;27(10):2075–7.

    PubMed  PubMed Central  CAS  Google Scholar 

  24. Ture U, Yasargil MG, Krisht AF. The arteries of the corpus callosum: a microsurgical anatomic study. Neurosurgery. 1996;39(6):1075–84; discussion 84-5. https://doi.org/10.1097/00006123-199612000-00001.

    Article  PubMed  CAS  Google Scholar 

  25. van der Zwan A, Hillen B, Tulleken CA, Dujovny M, Dragovic L. Variability of the territories of the major cerebral arteries. J Neurosurg. 1992;77(6):927–40. https://doi.org/10.3171/jns.1992.77.6.0927.

    Article  PubMed  Google Scholar 

  26. Picard L, Vignaud J, Lombardi G, Roland J. Radiological anatomy of the origin of the ophthalmic artery. Mod Probl Ophthalmol. 1975;14:164–9.

    PubMed  CAS  Google Scholar 

  27. Hassler W, Zentner J, Voigt K. Abnormal origin of the ophthalmic artery from the anterior cerebral artery: neuroradiological and intraoperative findings. Neuroradiology. 1989;31(1):85–7. https://doi.org/10.1007/bf00342037.

    Article  PubMed  CAS  Google Scholar 

  28. Baltsavias G, Turk Y, Valavanis A. Persistent ventral ophthalmic artery associated with supraclinoid internal carotid artery aneurysm: case report and review of the literature. J Neuroradiol. 2012;39(3):186–9. https://doi.org/10.1016/j.neurad.2011.08.002.

    Article  PubMed  Google Scholar 

  29. Hannequin P, Peltier J, Destrieux C, Velut S, Havet E, Le Gars D. The inter-optic course of a unique precommunicating anterior cerebral artery with aberrant origin of an ophthalmic artery: an anatomic case report. Surg Radiol Anat. 2013;35(3):269–71. https://doi.org/10.1007/s00276-012-1028-6.

    Article  PubMed  Google Scholar 

  30. Uchino A, Saito N, Kozawa E, Mizukoshi W, Inoue K. Persistent primitive olfactory artery: MR angiographic diagnosis. Surg Radiol Anat. 2011;33(3):197–201. https://doi.org/10.1007/s00276-010-0743-0.

    Article  PubMed  Google Scholar 

  31. Islak C, Ogut G, Numan F, Cokyuksel O, Kuday C. Persistent nonmigrated ventral primitive ophthalmic artery. Report on one case. J Neuroradiol. 1994;21(1):46–9.

    PubMed  CAS  Google Scholar 

  32. Honma Y, Ogawa T, Nagao S. Angiographically occult anomalous ophthalmic artery arising from the anterior cerebral artery. Acta Neurochir. 1997;139(5):480–1. https://doi.org/10.1007/bf01808888.

    Article  PubMed  CAS  Google Scholar 

  33. Belotti F, Ferrari M, Doglietto F, Cocchi MA, Lancini D, Buffoli B, et al. Ophthalmic artery originating from the anterior cerebral artery: anatomo-radiological study, histological analysis, and literature review. Neurosurg Rev. 2016;39(3):483–93. https://doi.org/10.1007/s10143-016-0715-x.

    Article  PubMed  Google Scholar 

  34. Uchino A, Saito N, Tanahashi N. Bilateral carotid-anterior cerebral artery anastomoses associated with bilateral ophthalmic arteries arising from the anastomotic arteries diagnosed by magnetic resonance angiography: a case report. Surg Radiol Anat. 2018;40(6):721–5. https://doi.org/10.1007/s00276-017-1953-5.

    Article  PubMed  Google Scholar 

  35. Matsuura K, Uchino A, Saito N, Ishida J, Suzuki T. Carotid-anterior cerebral artery (ACA) anastomosis associated with azygos ACA and ophthalmic artery arising from the middle meningeal artery: a case report. Surg Radiol Anat. 2020;42(2):211–4. https://doi.org/10.1007/s00276-019-02353-1.

    Article  PubMed  Google Scholar 

  36. Robinson LR. An unusual human anterior cerebral artery. J Anat. 1959;93(1):131–3.

    PubMed  PubMed Central  CAS  Google Scholar 

  37. Nutik S, Dilenge D. Carotid-anterior cerebral artery anastomosis. Case report. J Neurosurg. 1976;44(3):378–82. https://doi.org/10.3171/jns.1976.44.3.0378.

    Article  PubMed  CAS  Google Scholar 

  38. Mercier P, Velut S, Fournier D, Lescalie F, Guy G, Pillet J, et al. A rare embryologic variation: carotid-anterior cerebral artery anastomosis or infraoptic course of the anterior cerebral artery. Surg Radiol Anat. 1989;11(1):73–7. https://doi.org/10.1007/bf02102250.

    Article  PubMed  CAS  Google Scholar 

  39. Bosma NJ. Infra-optic course of anterior cerebral artery and low bifurcation of the internal carotid artery. Acta Neurochir. 1977;38(3–4):305–12. https://doi.org/10.1007/bf01401101.

    Article  PubMed  CAS  Google Scholar 

  40. Kessler LA. Unusual anomaly of the anterior cerebral artery: report of a case. Arch Neurol. 1979;36(8):509–10. https://doi.org/10.1001/archneur.1979.00500440079017.

    Article  PubMed  CAS  Google Scholar 

  41. Maurer J, Maurer E, Perneczky A. Surgically verified variations in the A1 segment of the anterior cerebral artery. Report of two cases. J Neurosurg. 1991;75(6):950–3. https://doi.org/10.3171/jns.1991.75.6.0950.

    Article  PubMed  CAS  Google Scholar 

  42. Given CA 2nd, Morris PP. Recognition and importance of an infraoptic anterior cerebral artery: case report. AJNR Am J Neuroradiol. 2002;23(3):452–4.

    PubMed  PubMed Central  Google Scholar 

  43. Isherwood I, Dutton J. Unusual anomaly of anterior cerebral artery. Acta Radiol Diagn (Stockh). 1969;9:345–51.

    PubMed  CAS  Google Scholar 

  44. Chua MH, Thomas AJ, Fusco MR, Ogilvy CS. An unruptured anterior communicating artery aneurysm with bilateral infraoptic anterior cerebral arteries. Case report and review of the literature. J Cerebrovasc Endovasc Neurosurg. 2014;16(4):368–73. https://doi.org/10.7461/jcen.2014.16.4.368.

    Article  PubMed  PubMed Central  Google Scholar 

  45. Yi Z, Sasaki T, Satoh D, Muruta T, Kitazawa K, Kobayashi S. Carotid-anterior cerebral artery anastomosis associated with Paraclinoid aneurysm and ophthalmic artery originating from middle meningeal artery: case report and consideration of terminology. World Neurosurg. 2016;88(689):e1–4. https://doi.org/10.1016/j.wneu.2015.11.021.

    Article  Google Scholar 

  46. Turnbull I. Agenesis of the internal carotid artery. Neurology. 1962;12:588–90. https://doi.org/10.1212/wnl.12.9.588.

    Article  PubMed  CAS  Google Scholar 

  47. Brismar J, Ackerman R, Roberson G. Anomaly of anterior cerebral artery. A case report and embryologic considerations. Acta Radiol Diagn (Stockh). 1977;18(2):154–60. https://doi.org/10.1177/028418517701800202.

    Article  PubMed  CAS  Google Scholar 

  48. Milenkovic Z. Anastomosis between internal carotid artery and anterior cerebral artery with other anomalies of the circle of Willis in a fetal brain. J Neurosurg. 1981;55(5):701–3. https://doi.org/10.3171/jns.1981.55.5.0701.

    Article  PubMed  CAS  Google Scholar 

  49. Bernini FP, Cioffi FA, Muras I, Rinaldi F. Carotid syphon—pericallosal arterial anastomosis. Case report. Acta Neurochir (Wien). 1982;66(1–2):61–9. https://doi.org/10.1007/bf01809304.

    Article  PubMed  CAS  Google Scholar 

  50. Senter HJ, Miller DJ. Interoptic course of the anterior cerebral artery associated with anterior cerebral artery aneurysm. Case report. J Neurosurg. 1982;56(2):302–4. https://doi.org/10.3171/jns.1982.56.2.0302.

    Article  PubMed  CAS  Google Scholar 

  51. Sheehy JP, Kendall BE, Thomas DG. Infraoptic course of the anterior cerebral artery associated with a pituitary tumor. Surg Neurol. 1983;20(2):97–9. https://doi.org/10.1016/0090-3019(83)90456-1.

    Article  PubMed  CAS  Google Scholar 

  52. Bollar A, Martinez R, Gelabert M, Garcia A. Anomalous origin of the anterior cerebral artery associated with aneurysm—embryological considerations. Neuroradiology. 1988;30(1):86. https://doi.org/10.1007/bf00341953.

    Article  PubMed  CAS  Google Scholar 

  53. Onishi H, Yamashita J, Enkaku F, Fujisawa H. Anomalous origin of the anterior cerebral artery and congenital skull dysplasia. Case report. Neurol Med Chir (Tokyo). 1992;32(5):296–9. https://doi.org/10.2176/nmc.32.296.

    Article  PubMed  CAS  Google Scholar 

  54. Sakai K, Asari S, Fujisawa M, Katagi R. Ruptured aneurysm arising from the anomalous anterior cerebral artery. Case report. Neurol Med Chir (Tokyo). 1992;32(11):846–50. https://doi.org/10.2176/nmc.32.846.

    Article  PubMed  CAS  Google Scholar 

  55. Ladzinski P, Maliszewski M, Majchrzak H. The accessory anterior cerebral artery: case report and anatomic analysis of vascular anomaly. Surg Neurol. 1997;48(2):171–4. https://doi.org/10.1016/s0090-3019(96)00421-1.

    Article  PubMed  CAS  Google Scholar 

  56. Singer RJ, Abe T, Taylor WH, Marks MP, Norbash AM. Intracavernous anterior cerebral artery origin with associated arteriovenous malformations: a developmental analysis: case report. Neurosurgery. 1997;40(4):829–31; discussion 31. https://doi.org/10.1097/00006123-199704000-00033.

    Article  PubMed  CAS  Google Scholar 

  57. Al-Qahtani S, Tampieri D, Brassard R, Sirhan D, Mellanson D. Coil embolization of an aneurysm associated with an infraoptic anterior cerebral artery in a child. AJNR Am J Neuroradiol. 2003;24(5):990–1.

    PubMed  PubMed Central  Google Scholar 

  58. Burbank NS, Morris PP. Unique anomalous origin of the left anterior cerebral artery. AJNR Am J Neuroradiol. 2005;26(10):2533–5.

    PubMed  PubMed Central  Google Scholar 

  59. Kilic K, Orakdogen M, Bakirci A, Berkman Z. Bilateral internal carotid to anterior cerebral artery anastomosis with anterior communicating artery aneurysm: technical case report. Neurosurgery. 2005;57(4 Suppl):E400; discussion E

    PubMed  Google Scholar 

  60. Akiyama Y, Okada T, Hayashi N, Yokoi T. Infraoptic course of the anterior cerebral artery originating from the extradural internal carotid artery associated with contralateral internal carotid artery agenesis and multiple intracerebral aneurysms. Neurol Med Chir (Tokyo). 2010;50(11):984–7. https://doi.org/10.2176/nmc.50.984.

    Article  PubMed  Google Scholar 

  61. Odake G. Carotid-anterior cerebral artery anastomosis with aneurysm: case report and review of the literature. Neurosurgery. 1988;23(5):654–8. https://doi.org/10.1227/00006123-198811000-00021.

    Article  PubMed  CAS  Google Scholar 

  62. Friedlander RM, Oglivy CS. Aneurysmal subarachnoid hemorrhage in a patient with bilateral A1 fenestrations associated with an azygos anterior cerebral artery. Case report and literature review. J Neurosurg. 1996;84(4):681–4. https://doi.org/10.3171/jns.1996.84.4.0681.

    Article  PubMed  CAS  Google Scholar 

  63. Fujimura M, Seki H, Sugawara T, Tomichi N, Oku T, Higuchi H. Anomalous internal carotid artery-anterior cerebral artery anastomosis associated with fenestration and cerebral aneurysm. Neurol Med Chir (Tokyo). 1996;36(4):229–33. https://doi.org/10.2176/nmc.36.229.

    Article  PubMed  CAS  Google Scholar 

  64. McLaughlin N, Bojanowski MW. Infraoptic course of anterior cerebral arteries associated with abnormal gyral segmentation. Case report. J Neurosurg. 2007;107(2):430–4. https://doi.org/10.3171/JNS-07/08/0430.

    Article  PubMed  Google Scholar 

  65. Stevenson CB, Chambless LB, Rini DA, Thompson RC. Bilateral infraoptic A1 arteries in association with a craniopharyngioma: case report and review of the literature. Surg Neurol Int. 2011;2:89. https://doi.org/10.4103/2152-7806.82371.

    Article  PubMed  PubMed Central  Google Scholar 

  66. Turkoglu E, Arat A, Patel N, Kertmen H, Baskaya MK. Anterior communicating artery aneurysm associated with an infraoptic course of anterior cerebral artery and rare variant of the persistent trigeminal artery: a case report and literature review. Clin Neurol Neurosurg. 2011;113(4):335–40. https://doi.org/10.1016/j.clineuro.2010.12.009.

    Article  PubMed  Google Scholar 

  67. Wong ST, Yuen SC, Fok KF, Yam KY, Fong D. Infraoptic anterior cerebral artery: review, report of two cases and an anatomical classification. Acta Neurochir. 2008;150(10):1087–96. https://doi.org/10.1007/s00701-008-0016-4.

    Article  PubMed  CAS  Google Scholar 

  68. Kim MS, Lee GJ. Persistent primitive olfactory artery: CT angiographic diagnosis and literature review for classification and clinical significance. Surg Radiol Anat. 2014;36(7):663–7. https://doi.org/10.1007/s00276-013-1239-5.

    Article  PubMed  Google Scholar 

  69. Moffat DB. A case of peristence of the primitive olfactory artery. Anat Anz. 1967;121(5):477–9.

    PubMed  CAS  Google Scholar 

  70. Kim MS. Persistent primitive olfactory artery connected with middle cerebral artery: case report. Surg Radiol Anat. 2013;35(9):849–52. https://doi.org/10.1007/s00276-013-1147-8.

    Article  PubMed  PubMed Central  Google Scholar 

  71. Lin WC, Hsu SW, Kuo YL, Feekes JA, Wang HC. Combination of olfactory course anterior cerebral artery and accessory middle cerebral artery (MCA) with occluded in situ MCA and related moyamoya phenomenon. Brain and Development. 2009;31(4):318–21. https://doi.org/10.1016/j.braindev.2008.05.008.

    Article  PubMed  Google Scholar 

  72. Nozaki K, Taki W, Kawakami O, Hashimoto N. Cerebral aneurysm associated with persistent primitive olfactory artery aneurysm. Acta Neurochir. 1998;140(4):397–401; discussion −2. https://doi.org/10.1007/s007010050114.

    Article  PubMed  CAS  Google Scholar 

  73. Tsuji T, Abe M, Tabuchi K. Aneurysm of a persistent primitive olfactory artery. Case report. J Neurosurg. 1995;83(1):138–40. https://doi.org/10.3171/jns.1995.83.1.0138.

    Article  PubMed  CAS  Google Scholar 

  74. Tsutsumi S, Shimizu Y, Nonaka Y, Abe Y, Yasumoto Y, Ito M, et al. Arteriovenous fistula arising from the persistent primitive olfactory artery with dual supply from the bilateral anterior ethmoidal arteries. Neurol Med Chir (Tokyo). 2009;49(9):407–9. https://doi.org/10.2176/nmc.49.407.

    Article  PubMed  Google Scholar 

  75. Uchino A, Sawada A, Takase Y, Kudo S. Persistent primitive olfactory artery: diagnosis with MR angiography. Clin Imaging. 2001;25(4):258–61. https://doi.org/10.1016/s0899-7071(01)00294-7.

    Article  PubMed  CAS  Google Scholar 

  76. Vasovic L, Trandafilovic M, Vlajkovic S, Jovanovic I, Ugrenovic S. Persistent primitive olfactory artery in Serbian population. Biomed Res Int. 2013;2013:903460. https://doi.org/10.1155/2013/903460.

    Article  PubMed  PubMed Central  Google Scholar 

  77. Yamamoto T, Suzuki K, Yamazaki T, Tsuruta W, Tsurubuchi T, Matsumura A. Persistent primitive olfactory artery aneurysm. Neurol Med Chir (Tokyo). 2009;49(7):303–5. https://doi.org/10.2176/nmc.49.303.

    Article  PubMed  Google Scholar 

  78. Signorelli F, Scholtes F, Kauffmann C, McLaughlin N, Bojanowski MW. Dural artery from the anterior cerebral artery to the planum sphenoidale. Acta Neurochir. 2010;152(10):1807–8. https://doi.org/10.1007/s00701-010-0716-4.

    Article  PubMed  Google Scholar 

  79. Horie N, Morikawa M, Fukuda S, Hayashi K, Suyama K, Nagata I. New variant of persistent primitive olfactory artery associated with a ruptured aneurysm. J Neurosurg. 2012;117(1):26–8. https://doi.org/10.3171/2012.3.JNS111932.

    Article  PubMed  Google Scholar 

  80. Baptista AG. Studies of the arteries of the brain. II. The anterior cerebral artery: some anatomic features and their clinical implications. Neurology. 1963;13:825–35.

    Article  PubMed  CAS  Google Scholar 

  81. LeMay M, Gooding CA. The clinical significance of the azygos anterior cerebral artery (a.C.a.). Am J Roentgenol Radium Therapy, Nucl Med. 1966;98(3):602–10. https://doi.org/10.2214/ajr.98.3.602.

    Article  CAS  Google Scholar 

  82. Windle BC. The arteries forming the circle of Willis. J Anat Physiol. 1888;22(Pt 2):289–93.

    PubMed  PubMed Central  CAS  Google Scholar 

  83. Katz RW, Horoupian DS, Zingesser L. Aneurysm of azygous anterior cerebral artery. A case report. J Neurosurg. 1978;48(5):804–8. https://doi.org/10.3171/jns.1978.48.5.0804.

    Article  PubMed  CAS  Google Scholar 

  84. Huber P, Braun J, Hirschmann D, Agyeman JF. Incidence of berry aneurysms of the unpaired pericallosal artery: angiographic study. Neuroradiology. 1980;19(3):143–7. https://doi.org/10.1007/bf00342389.

    Article  PubMed  CAS  Google Scholar 

  85. Hashizume K, Nukui H, Horikoshi T, Kaneko M, Fukamachi A. Giant aneurysm of the azygos anterior cerebral artery associated with acute subdural hematoma. Case report. Neurol Med Chir (Tokyo). 1992;32(9):693–7. https://doi.org/10.2176/nmc.32.693.

    Article  PubMed  CAS  Google Scholar 

  86. Kanemoto Y, Tanaka Y, Nonaka M, Hironaka Y. Giant aneurysm of the azygos anterior cerebral artery. Case report. Neurol Med Chir (Tokyo). 2000;40(9):472–5. https://doi.org/10.2176/nmc.40.472.

    Article  PubMed  CAS  Google Scholar 

  87. Kondo A, Koyama T, Ishikawa J, Iwaki K, Yamasaki T. Ruptured aneurysm of an azygos anterior cerebral artery. Neuroradiology. 1979;17(4):227–9. https://doi.org/10.1007/bf00342754.

    Article  PubMed  CAS  Google Scholar 

  88. Niizuma H, Kwak R, Uchida K, Suzuki J. Aneurysms of the azygos anterior cerebral artery. Surg Neurol. 1981;15(3):225–8. https://doi.org/10.1016/0090-3019(81)90150-6.

    Article  PubMed  CAS  Google Scholar 

  89. Hayashi M, Kobayashi H, Kawano H, Handa Y, Kabuto M. Giant aneurysm of an azygos anterior cerebral artery: report of two cases and review of the literature. Neurosurgery. 1985;17(2):341–4. https://doi.org/10.1227/00006123-198508000-00020.

    Article  PubMed  CAS  Google Scholar 

  90. Handa J, Matsuda M, Koyama T, Handa H, Kikuchi H. Internal carotid aneurysm associated with multiple anomalies of cerebral arteries. Neuroradiology. 1971;2(4):230–3. https://doi.org/10.1007/bf00337573.

    Article  PubMed  CAS  Google Scholar 

  91. Yanaka K, Shirai S, Shibata Y, Nose T. Ruptured aneurysm at the origin of the median artery of the corpus callosum associated with accessory middle cerebral artery—Case report. Neurol Med Chir (Tokyo). 2000;40(10):511–4. https://doi.org/10.2176/nmc.40.511.

    Article  PubMed  CAS  Google Scholar 

  92. Gibbons K, Hopkins LN, Heros RC. Occlusion of an “accessory” distal anterior cerebral artery during treatment of anterior communicating artery aneurysms. Report of two cases. J Neurosurg. 1991;74(1):133–5. https://doi.org/10.3171/jns.1991.74.1.0133.

    Article  PubMed  CAS  Google Scholar 

  93. Kwak R, Niizuma H, Hatanaka M, Suzuki J. Anterior communicating artery aneurysms with associated anomalies. J Neurosurg. 1980;52(2):162–4. https://doi.org/10.3171/jns.1980.52.2.0162.

    Article  PubMed  CAS  Google Scholar 

  94. Ogawa A, Suzuki M, Sakurai Y, Yoshimoto T. Vascular anomalies associated with aneurysms of the anterior communicating artery: microsurgical observations. J Neurosurg. 1990;72(5):706–9. https://doi.org/10.3171/jns.1990.72.5.0706.

    Article  PubMed  CAS  Google Scholar 

  95. Crompton MR. The pathology of ruptured middle-cerebral aneurysms with special reference to the differences between the sexes. Lancet. 1962;2(7253):421–5. https://doi.org/10.1016/s0140-6736(62)90281-7.

    Article  PubMed  CAS  Google Scholar 

  96. Teal JS, Rumbaugh CL, Bergeron RT, Segall HD. Angiographic demonstration of fenestrations of the intradural intracranial arteries. Radiology. 1973;106(1):123–6. https://doi.org/10.1148/106.1.123.

    Article  PubMed  CAS  Google Scholar 

  97. Ito J, Washiyama K, Kim CH, Ibuchi Y. Fenestration of the anterior cerebral artery. Neuroradiology. 1981;21(5):277–80. https://doi.org/10.1007/bf02100160.

    Article  PubMed  CAS  Google Scholar 

  98. Kobayashi S, Yuge T, Sugita Y, Kuratomi A, Katayama M, Iryo O, et al. Azygos anterior cerebral artery aneurysm associated with fenestration of the anterior cerebral artery. Kurume Med J. 1986;33(3):149–53. https://doi.org/10.2739/kurumemedj.33.149.

    Article  PubMed  CAS  Google Scholar 

  99. Korosue K, Kuwamura K, Okuda Y, Tamaki N, Matsumoto S. Saccular aneurysm arising from a fenestrated anterior cerebral artery. Surg Neurol. 1983;19(3):273–5. https://doi.org/10.1016/s0090-3019(83)80015-9.

    Article  PubMed  CAS  Google Scholar 

  100. Matsumura M, Nojiri K. Ruptured anterior communicating artery aneurysms associated with fenestration of the anterior cerebral artery. Surg Neurol. 1984;22(4):371–6. https://doi.org/10.1016/0090-3019(84)90142-3.

    Article  PubMed  CAS  Google Scholar 

  101. Minakawa T, Kawamata M, Hayano M, Kawakami K. Aneurysms associated with fenestrated anterior cerebral arteries. Report of four cases and review of the literature. Surg Neurol. 1985;24(3):284–8. https://doi.org/10.1016/0090-3019(85)90040-0.

    Article  PubMed  CAS  Google Scholar 

  102. Ogasawara H, Inagawa T, Yamamoto M, Kamiya K. Aneurysm in a fenestrated anterior cerebral artery. Case report. Neurol Med Chir (Tokyo). 1988;28(6):575–8. https://doi.org/10.2176/nmc.28.575.

    Article  PubMed  CAS  Google Scholar 

  103. Yamada T, Inagawa T, Takeda T. Ruptured aneurysm at the anterior cerebral artery fenestration. Case report. J Neurosurg. 1982;57(6):826–8. https://doi.org/10.3171/jns.1982.57.6.0826.

    Article  PubMed  CAS  Google Scholar 

  104. Fawcett E, Blachford JV. The circle of Willis: an examination of 700 specimens. J Anat Physiol. 1905;40(Pt 1):632–70.

    Google Scholar 

  105. Vucetic RR. Segmental duplication of the fetal anterior cerebral artery. J Anat. 1998;192(Pt 3):431–4. https://doi.org/10.1046/j.1469-7580.1998.19230431.x.

    Article  PubMed  PubMed Central  Google Scholar 

  106. Dimmick SJ, Faulder KC. Fenestrated anterior cerebral artery with associated arterial anomalies. Case reports and literature review. Interv Neuroradiol. 2008;14(4):441–5. https://doi.org/10.1177/159101990801400410.

    Article  PubMed  CAS  Google Scholar 

  107. Fujimoto S, Murakami M. Anomalous branch of the internal carotid artery supplying circulation of the anterior cerebral artery. Case report. J Neurosurg. 1983;58(6):941–6. https://doi.org/10.3171/jns.1983.58.6.0941.

    Article  PubMed  CAS  Google Scholar 

  108. Hillard VH, Musunuru K, Nwagwu C, Das K, Murali R, Zablow B, et al. Treatment of an anterior communicating artery aneurysm through an anomalous anastomosis from the cavernous internal carotid artery. J Neurosurg. 2002;97(6):1432–5. https://doi.org/10.3171/jns.2002.97.6.1432.

    Article  PubMed  Google Scholar 

  109. Yurt A, Ucar K, Ozer F, Oran I, Arda N. A rare embryologic variation: anterior communicating artery aneurysm associated with carotid-anterior cerebral artery anastomosis or infraoptic course of the anterior cerebral artery. Clin Med Case Rep. 2008;1:123–5. https://doi.org/10.4137/ccrep.s918.

    Article  PubMed  PubMed Central  Google Scholar 

  110. Chakraborty S, Fanning NF, Lee SK, Terbrugge KG. Bilateral infraoptic origin of anterior cerebral arteries: a rare anomaly and its embryological and clinical significance. Interv Neuroradiol. 2006;12(2):155–9. https://doi.org/10.1177/159101990601200210.

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  111. Rosenorn J, Ahlgren P, Ronde F. Pre-optic origin of the anterior cerebral artery. Neuroradiology. 1985;27(3):275–7. https://doi.org/10.1007/bf00344501.

    Article  PubMed  CAS  Google Scholar 

  112. Kim MS, Sim SY. Infraoptic anterior cerebral artery: case series report and literature review. Surg Radiol Anat. 2016;38(8):887–91. https://doi.org/10.1007/s00276-016-1651-8.

    Article  PubMed  Google Scholar 

  113. Ji C, Ahn JG. Infraoptic course of both anterior cerebral arteries. J Korean Neurosurg Soc. 2010;47(1):71–3. https://doi.org/10.3340/jkns.2010.47.1.71.

    Article  PubMed  PubMed Central  Google Scholar 

  114. Fisher AG. A case of complete absence of both internal carotid arteries, with a preliminary note on the developmental history of the stapedial artery. J Anat Physiol. 1913;48(Pt 1):37–46.

    PubMed  PubMed Central  CAS  Google Scholar 

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Bonasia, S., Robert, T., Bojanowski, M.W. (2023). Embryology, Anatomy, and Variations of the Anterior Cerebral Artery. In: Robert, T., Bonasia, S., Bojanowski, M.W. (eds) Anatomy of Cranial Arteries, Embryology and Variants. Springer, Cham. https://doi.org/10.1007/978-3-031-32913-5_8

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