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Scabies Multi-Omics to Identify Novel Diagnostic or Therapeutic Targets

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Scabies

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Abstract

In recent decades, substantial progress has been made in genome and transcriptome sequencing, assembly, annotation and analyses of many parasites with socioeconomic impact. This progress has upgraded our understanding of many parasitic pathogens at the molecular level. However, compared with ticks and insects, the research fields of functional genomics, transcriptomics, proteomics and metabolomics of free-living and parasitic mites are still in development. In particular, there are major gaps in our knowledge of the molecular biology of the scabies mite. Currently, molecular resources (including draft genomic, transcriptomic and proteomic databases) are being generated to provide a foundation that will allow us to begin exploring the molecular biology of this species. In this chapter, we provide an update on the recent advances in this field.

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Authors and Affiliations

  1. Scabies Laboratory, Infection and Inflammation Program, QIMR Berghofer Medical Research Institute, Brisbane, Australia

    Katja Fischer, Hieng Lu & Deepani D. Fernando

  2. Faculty of Veterinary and Agricultural Sciences, The University of Melbourne, Parkville, VIC, Australia

    Robin B. Gasser

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  1. Katja Fischer
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  2. Hieng Lu
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  3. Deepani D. Fernando
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  4. Robin B. Gasser
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Correspondence to Katja Fischer .

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Editors and Affiliations

  1. QIMR Berghofer Medical Research Institut, Herston, QLD, Australia

    Katja Fischer

  2. UPE-Université Paris-Est, Service de Dermatologie, Hôpital Henri Mondor, EA 7379 EpiDermE et INSERM CIC 1430, Créteil, France

    Olivier Chosidow

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Fischer, K., Lu, H., Fernando, D.D., Gasser, R.B. (2023). Scabies Multi-Omics to Identify Novel Diagnostic or Therapeutic Targets. In: Fischer, K., Chosidow, O. (eds) Scabies. Springer, Cham. https://doi.org/10.1007/978-3-031-26070-4_6

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