Abstract
According to the World Health Organization (WHO), Salmonella is among the pathogens with the greatest impact on the human population and has been linked to outbreaks and sporadic cases of human foodborne diseases worldwide. Typically, humans become infected through ingesting foods contaminated with animal feces or cross-contaminated by other sources. Thus, we reported in this chapter the distribution and prevalence of antibiotic-resistant and antimicrobial resistance genes (ARGs) among non-typhoidal Salmonella (NTS) isolated from farm animals and animal products in Africa and identified key knowledge gaps regarding their spread. An online database (PubMed) was used to search for literature using the subject terms: “Salmonella” AND “Resistance” AND “Africa.” The predefined criteria to assess the literature and extract data included “country,” “sampling period,” “the origin and type of samples,” “Salmonella serotype,” “the associated ARGs,” “the sequence type (ST) of the identified strain,” “the antimicrobial resistance profile,” and “reference (authorship and year).” Eighty studies conducted in African countries met the inclusion criteria. Over 3391 Salmonella spp. isolates were recorded from farm animals and animal-based foods derived from cattle, swine, and poultry. Salmonella Enteritidis, S. Typhimurium, and S. Kentucky were the most commonly recorded serotypes (457, 441, and 328 strains, respectively). Salmonella spp. showed different antibiotic resistance patterns, including resistance to ampicillin, cephalosporins, streptomycin, tetracycline, trimethoprim-sulfamethoxazole, chloramphenicol, gentamicin, ciprofloxacin, and nalidixic acid. Salmonella spp. isolated from different farm animals and animal food products in many African countries often show resistance to several antibiotics. Therefore, monitoring antibiotic resistance in this genus is important to apply adequate control strategies.
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Zahra, B., Assia, M., Abdelaziz, T. (2023). Distribution and Prevalence of Antimicrobial Resistance of NTS Salmonella Isolated from Farm Animals and Animal Food Products in Africa. In: Abia, A.L.K., Essack, S.Y. (eds) Antimicrobial Research and One Health in Africa. Springer, Cham. https://doi.org/10.1007/978-3-031-23796-6_5
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