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matRadiomics: From Biomedical Image Visualization to Predictive Model Implementation

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Image Analysis and Processing. ICIAP 2022 Workshops (ICIAP 2022)

Part of the book series: Lecture Notes in Computer Science ((LNCS,volume 13373))

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Abstract

The development of radiomics tools allows the extraction of quantitative features from medical images, thus enhancing the available information for clinicians. However, to date, these tools do not allow the user to complete the radiomics workflow by stopping at the feature extraction step. Therefore, a new software, namely matRadiomics, was developed as a user-friendly tool with the aim of allowing the user to carry out all the steps of a radiomics study. Using a single tool, i) biomedical images can be imported and inspected, ii) the target can be identified and segmented, iii) features can be extracted from the target, iv) reduced and selected, and v) used to build a predictive model using machine learning algorithms. As result, two different feature extractors can be chosen, a Matlab-based extractor, and the Pyradiomics extractor naturally integrated into matRadiomics. Extracted features can be selected using a hybrid descriptive-inferential method, while selected features can be used to train three different classifiers: Linear Discriminant Analysis, K-Nearest Neighbors, and Support Vector Machines. Models’ validation is performed using K-Fold Cross Validation and K-Fold Stratified Cross Validation. Finally, the performance metrics of each model are shown in the graphical interface of matRadiomics. In conclusion, the result of this study was the development, implementation, and validation of an innovative and complete radiomics tool that accompanies the researcher throughout the whole radiomics workflow.

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Authors and Affiliations

  1. Institute of Molecular Bioimaging and Physiology, National Research Council (IBFM-CNR), 90015, Cefalù, Italy

    Giovanni Pasini, Giorgio Russo & Alessandro Stefano

  2. Department of Mechanical and Aerospace Engineering, Sapienza University of Rome, Eudossiana 18, 00184, Rome, Italy

    Giovanni Pasini, Fabiano Bini & Franco Marinozzi

Authors
  1. Giovanni Pasini
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  2. Fabiano Bini
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  3. Giorgio Russo
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  4. Franco Marinozzi
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  5. Alessandro Stefano
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Correspondence to Alessandro Stefano .

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Editors and Affiliations

  1. National Research Council, Lecce, Italy

    Pier Luigi Mazzeo

  2. Università Politecnica delle Marche, Ancona, Italy

    Emanuele Frontoni

  3. Boston University, Boston, MA, USA

    Stan Sclaroff

  4. National Research Council, Lecce, Italy

    Cosimo Distante

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Pasini, G., Bini, F., Russo, G., Marinozzi, F., Stefano, A. (2022). matRadiomics: From Biomedical Image Visualization to Predictive Model Implementation. In: Mazzeo, P.L., Frontoni, E., Sclaroff, S., Distante, C. (eds) Image Analysis and Processing. ICIAP 2022 Workshops. ICIAP 2022. Lecture Notes in Computer Science, vol 13373. Springer, Cham. https://doi.org/10.1007/978-3-031-13321-3_33

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  • DOI: https://doi.org/10.1007/978-3-031-13321-3_33

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  • Print ISBN: 978-3-031-13320-6

  • Online ISBN: 978-3-031-13321-3

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