Overview
- Fills a gap in published literature on specifics of TDM and Toxicity
- Covers forensic toxicology, nanotoxicology, toxicogenomics and toxinology
- Discusses pharmacokinetics and pharmacogenomics
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Table of contents (21 chapters)
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Front Matter
Keywords
- pharmacokinetics
- drug dose adjustment
- pharmacogenomics
- biological matrices
- critical care drug dosage
- anticonvulsants
- antipsychotics dosing
- antidepressant dosing
- immunosuppressants
- immunodeficiency
- kidney and hepatic drug dosing
- cancer chemotherapy
- forensic toxicology
- banned sports substances
- reactive metabolites
- nanotoxicology
- toxicogenomics
- toxinology
About this book
This book gives an overview of therapeutic drug monitoring (TDM) and its clinical application. It also highlights recent advances in toxicological studies, as they relate to therapeutic drug monitoring.
This is one of the few books available on the market that covers TDM. Therapeutic drug monitoring (TDM) is a clinical decision-making tool that enables dosage regimen adjustments based on clinical and laboratory measurements. TDM not only involves the measuring of drug concentrations but also interpretation of the results. There is a strong correlation between drug concentrations in body fluids and outcome than between dose and outcome. The chapters include coverage of analytical techniques, pharmacokinetics, therapeutic indices, artificial intelligence and recent advances in toxicological studies.
The book fills a gap in published literature and provides reliable information on;
- Analytical techniques in TDM and clinical toxicology
- TDM and pharmacokinetic studies
- TDM of drugs with narrow therapeutic indices
- Artificial intelligence in TDM and clinical toxicology
- Future directions and challenges
Editors and Affiliations
About the editors
Seth Kwabena Amponsah (PhD) is a Senior Lecturer and Head of Department of Medical Pharmacology, University of Ghana Medical School. He has an MPhil and PhD in Pharmacology. He has over 10 years' experience in teaching and research. His research focus includes Clinical Pharmacology (infectious disease and antimicrobial stewardship): prudent use of antimicrobials, antimicrobial level monitoring, and efficacy of antimicrobials in patients. He also has experience in therapeutic drug monitoring, population pharmacokinetic modeling; non-compartment pharmacokinetic and pharmacodynamic estimation; and pharmacokinetic evaluation of new drug formulations. He has published over 40 research articles, 3 book chapters and several conference abstracts.
Dr. Yashwant Pathak has over 13 years of versatile administrative experience in an institution of higher education as Dean (and over 30 years as faculty and as a researcher in higher education after his Ph.D). He now holds the position for Associate Dean for Faculty Affairs and tenured professor of Pharmaceutical Sciences. Dr. Pathak is an internationally recognized scholar, researcher and educator in the areas of health care education, nanotechnology, drug delivery systems and nutraceuticals. He has published extensively with over 50 edited volumes in the area of nanotechnology, drug delivery systems, artificial neural networks, conflict management and cultural studies. He has over 300 research papers, reviews, and chapters in books and presented in many national and international conferences. He is also actively involved many nonprofit organizations, to mention a few, Hindu Swayamsevak Sangh (USA), Sewa International (USA), International accreditation council for Dharma Schools and colleges, International commission for Human rights and religious freedom.
Bibliographic Information
Book Title: Recent Advances in Therapeutic Drug Monitoring and Clinical Toxicology
Editors: Seth Kwabena Amponsah, Yashwant V. Pathak
DOI: https://doi.org/10.1007/978-3-031-12398-6
Publisher: Springer Cham
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG 2022
Hardcover ISBN: 978-3-031-12397-9Published: 26 October 2022
Softcover ISBN: 978-3-031-12400-6Published: 27 October 2023
eBook ISBN: 978-3-031-12398-6Published: 25 October 2022
Edition Number: 1
Number of Pages: XVIII, 381
Number of Illustrations: 2 b/w illustrations, 41 illustrations in colour
Topics: Pharmacology/Toxicology, Biomedicine, general, Pharmaceutical Sciences/Technology