Skip to main content

Tissue Plasminogen Activator (tPA)

  • Chapter
  • First Online:
Neuroimaging Pharmacopoeia

Abstract

This chapter reviews the neuroimaging features of the potential effects of tissue plasminogen activator (tPA).

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 129.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 169.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 249.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Similar content being viewed by others

Suggested Reading

  • Derex L, Hermier M, Adeleine P, Pialat J-B, Wiart M, Bertheze’ne Y, Philippeau F, Honnorat J, Froment J-C, Trouillas P, Nighoghossian N. Clinical and imaging predictors of intracerebral haemorrhage in stroke patients treated with intravenous tissue plasminogen activator. J Neurol Neurosurg Psychiatry. 2005;76:70–5.

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  • Gore JM, Sloan M, Price TR, et al. Intracerebral hemorrhage, cerebral infarction, and subdural hematoma after acute myocardial infarction and thrombolytic therapy in the thrombolysis in myocardial infarction study. Thrombolysis in myocardial infarction, phase II, pilot and clinical trial. Circulation. 1991;83:448–59.

    Article  PubMed  CAS  Google Scholar 

  • Kase CS, Williams JP, Wyatt DA, et al. Lobar intracerebral hematomas: clinical and CT analysis of 22 cases. Neurology. 1982;32:1146–50.

    Article  PubMed  CAS  Google Scholar 

  • Mould WA, Carhuapoma JR, Muschelli J, et al. Minimally invasive surgery plus recombinant tissue-type plasminogen activator for intracerebral hemorrhage evacuation decreases perihematomal edema. Stroke. 2013;44(3):627–34.

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  • O’Connor CM, Califf RM, Massey EW, et al. Stroke and acute myocardial infarction in the thrombolytic era: clinical correlates and long-term prognosis. J Am Coll Cardiol. 1990;16:533–40.

    Article  PubMed  Google Scholar 

  • Quinones-Hinojosa A, Gulati M, Singh V, Lawton MT. Spontaneous intracerebral hemorrhage due to coagulation disorders. Neurosurg Focus. 2003;15(4):E3.

    Article  PubMed  Google Scholar 

  • Wijdicks EF, Jack CR Jr. Intracerebral hemorrhage after fibrinolytic therapy for acute myocardial infarction. Stroke. 1993;24:554–7.

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Daniel Thomas Ginat .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2022 Springer Nature Switzerland AG

About this chapter

Check for updates. Verify currency and authenticity via CrossMark

Cite this chapter

Watkins, E., Small, J.E., Ginat, D.T. (2022). Tissue Plasminogen Activator (tPA). In: Ginat, D.T., Small, J.E., Schaefer, P.W. (eds) Neuroimaging Pharmacopoeia. Springer, Cham. https://doi.org/10.1007/978-3-031-08774-5_45

Download citation

  • DOI: https://doi.org/10.1007/978-3-031-08774-5_45

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-031-08773-8

  • Online ISBN: 978-3-031-08774-5

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics