Abstract
Both tricyclic antidepressants (TCAs) and serotonin-norepinephrine reuptake inhibitors (SNRIs) are medications that were initially intended to treat mood disorders, but their utility has broadened to include treatment of various chronic and neuropathic pain conditions. Consequently, many patients with chronic pain are maintained on one of these medications as a part of their outpatient regimen, and the inpatient chronic pain consultant should be familiar with the management of these medications when chronic pain patients present as inpatients.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Similar content being viewed by others
References
Sindrup SH, Otto M, Finnerup NB, Jensen TS. Antidepressants in the treatment of neuropathic pain. Basic Clin Pharmacol Toxicol. 2005;96(6):399–409.
Reid IC, Stewart CA. How antidepressants work: New perspectives on the pathophysiology of depressive disorder. Br J Psychiatry. 2001;178(4):299–303.
Shelton RC. Serotonin and norepinephrine reuptake inhibitors. Handb Exp Pharmacol. 2018:1–36.
Welsch P, Üçeyler N, Klose P, Walitt B, Häuser W. Serotonin and noradrenaline reuptake inhibitors (SNRIs) for fibromyalgia. Cochrane Database Syst Rev. 2018;2(2):CD010292.
Bainum TB, Fike DS, Mechelay D, Haase KK. Effect of abrupt discontinuation of antidepressants in critically ill hospitalized adults. pharmacotherapy. J Hum Pharmacol Drug Therap. 2017;37(10):1231–40.
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2022 Springer Nature Switzerland AG
About this chapter
Cite this chapter
Kuoni, S., James, M., Sobey, C.M. (2022). Tricyclic Antidepressants and Serotonin-Norepinephrine Reuptake Inhibitors. In: Edwards, D.A., Gulur, P., Sobey, C.M. (eds) Hospitalized Chronic Pain Patient . Springer, Cham. https://doi.org/10.1007/978-3-031-08376-1_35
Download citation
DOI: https://doi.org/10.1007/978-3-031-08376-1_35
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-031-08375-4
Online ISBN: 978-3-031-08376-1
eBook Packages: MedicineMedicine (R0)