Skip to main content
SpringerLink
Log in

Renovascular Hypertension, Vasculitis, and Aortic Coarctation

  • Reference work entry
  • First Online:
Pediatric Hypertension

  • 730 Accesses

Abstract

High blood pressure in children may be caused by vascular abnormalities in the aorta such as coarctation or mid-aortic syndrome, or in the renal arteries in a significant proportion of cases. The underlying causes are mostly unknown but thought to be an abnormality in the blood vessel wall, often called fibromuscular dysplasia. Inflammation in the vessel wall, vasculitis, can also cause hypertension. Vascular abnormalities are important to diagnose as in most cases they are amenable to surgery or angioplasty.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution

Institutional subscriptions

Similar content being viewed by others

References

  • Abdulsamea S, Anderson P, Biassoni L, Brennan E, McLaren CA, Marks SD, Roebuck DJ, Selim S, Tullus K (2010) Pre- and postcaptopril renal scintigraphy as a screening test for renovascular hypertension in children. Pediatr Nephrol 25(2):317–322

    Article  Google Scholar 

  • Alexander A, Richmond L, Geary D, Salle JLP, Amaral J, Connolly B (2017) Outcomes of percutaneous transluminal angioplasty for pediatric renovascular hypertension. J Pediatr Surg 52(3):395–399

    Article  Google Scholar 

  • Baker-Smith CM, Flinn SK, Flynn JT, Kaelber DC, Blowey D, Carrol AE, Daniels SR, de Ferranti SD, Dionne JM, Falkner B, Gidding SS, Goodwin C, Leu MG, Powers ME, Rea C, Samuels J, Simasek M, Thakker VV, Urbina EM (2018) Diagnosis, evaluation, and management of high blood pressure in children and adolescents. Pediatrics 14142(2):e20182096

    Article  Google Scholar 

  • Bayrak A, Numan F, Cantasdemir M, Bas A (2008) Percutaneous balloon angioplasty of renovascular hypertension in pediatric cases. Acta Chir Belg 108(6):708–714

    Article  Google Scholar 

  • Blockmans D (2011) PET in vasculitis. Ann N Y Acad Sci 1228:64–70

    Article  Google Scholar 

  • Blondin D, Lanzman R, Schellhammer F, Oels M, Grotemeyer D, Baldus SE, Rump LC, Sandmann W, Voiculescu A (2010) Fibromuscular dysplasia in living renal donors: still a challenge to computed tomographic angiography. Eur J Radiol 75(1):67–71

    Article  CAS  Google Scholar 

  • Bofinger A, Hawley C, Fisher P, Daunt N, Stowasser M, Gordon R (2001) Polymorphisms of the renin-angiotensin system in patients with multifocal renal arterial fibromuscular dysplasia. J Hum Hypertens 15(3):185–190

    Article  CAS  Google Scholar 

  • Brown BP, Karmazyn B (2014) Renal sonography with Doppler – not shown to be adequate as a screening tool for renovascular hypertension. Pediatr Radiol 44(8):1042–1043

    Article  Google Scholar 

  • Castelli PK, Dillman JR, Kershaw DB, Khalatbari S, Stanley JC, Smith EA (2014) Renal sonography with Doppler for detecting suspected pediatric renin-mediated hypertension – is it adequate? Pediatr Radiol 44(1):42–49

    Article  Google Scholar 

  • Chen T-Y, Huang L-T, Liang C-D, Ko S-F, Fang C-Y (2002) Renal artery stenosis presenting with status epilepticus: a report of one case. Acad Emerg Med 9(12):1445–7. https://doi.org/10.1111/j.1553-2712.2002.tb01618.x

  • Chhadia S, Cohn RA, Vural G, Donaldson JS (2013) Renal Doppler evaluation in the child with hypertension: a reasonable screening discriminator? Pediatr Radiol 43(12):1549–1556

    Article  Google Scholar 

  • Coleman DM et al (2020) Histologic and morphologic character of pediatric renal artery occlusive disease. J Vasc Surg 73(1):161–171. https://doi.org/10.1016/j.jvs.2020.02.046

  • Davis FM, Eliason JL, Ganesh SK, Blatt NB, Stanley JC, Coleman DM (2016) Pediatric nonaortic arterial aneurysms. J Vasc Surg 63(2):466–476

    Article  Google Scholar 

  • de Leeuw PW (2002) On the significance of renal vein renins in renovascular hypertension. J Hypertens 20(5):843–5. https://doi.org/10.1097/00004872-200205000-00015

  • De Souza AW, de Carvalho JF (2014) Diagnostic and classification criteria of Takayasu arteritis. J Autoimmun 48-48:79–83

    Article  Google Scholar 

  • Di Monaco S et al (2018) Genomics of fibromuscular dysplasia. Int J Mol Sci 19(5):1526. https://doi.org/10.3390/ijms19051526

  • Di Santo M, Stelmaszewski EV, Villa A (2018) Takayasu artertis in paediatrics. Cardiol Young 28(2=3):354–361

    Article  Google Scholar 

  • Duprey A, Chavent B, Meyer-Bisch V, Varin T, Albertini JN, Favre JP, Barral X, Ricco JB (2016) Editor’s choice – ex vivo renal artery repair with kidney autotransplantation for renal artery branch aneurysms: long-term results of sixty-seven procedures. Eur J Vasc Endovasc Surg 51(6):872–879

    Article  CAS  Google Scholar 

  • Eklof H, Ahlstrom H, Magnusson A, Andersson LG, Andren B, Hagg A, Bergqvist D, Nyman R (2006) A prospective comparison of duplex ultrasonography, captopril renography, MRA, and CTA in assessing renal artery stenosis. Acta Radiol 47(8):764–774

    Article  CAS  Google Scholar 

  • Eliason JL, Coleman DM, Criado E, Kershaw DB, Blatt NB, Williams DM, Dasika NL, Cho KJ, Stanley JC (2016) Remedial operations for failed endovascular therapy of 32 renal artery stenoses in 24 children. Pediatr Nephrol 31(5):809–817

    Article  Google Scholar 

  • Estepa R, Gallego N, Orte L, Belanger A, Aracil E, Ortuno J (2001) Pediatric renovascular hypertension. Pediatr Nephrol 16(6):529–531

    CAS  Google Scholar 

  • Forsey J, Dhandayuthapani G, Hamilton M, Martin R, Tizard E, Ramanan A (2011) Takayasu arteritis: key clinical factors for early diagnosis. Arch Dis Child Educ Pract Ed 96(5):176–182

    Article  CAS  Google Scholar 

  • Ganigara M, Doshi A, Naimi I, Mahadevaiah G, Buddhe S, Chikkabyrappa S (2019) Preoperative psychology, imaging and management of coarctation of aorta in children. Semin Cardiothorac Vasc Anesth 23(4):379–386

    Article  Google Scholar 

  • Ghirardo G, De FM, Vidal E, Vidoni A, Ramondo G, Benetti E, Motta R, Ferraro A, Zanon GF, Miotto D, Murer L (2014) Transplant renal artery stenosis in children: risk factors and outcome after endovascular treatment. Pediatr Nephrol 29(3):461–467

    Article  Google Scholar 

  • Green R, Gu X, Kline-Rogers E, Froehlich J, Mace P, Gray B, Katzen B, Olin J, Gornik HL, Cahill AM, Meyers KE (2016) Differences between the pediatric and adult presentation of fibromuscular dysplasia: results from the US registry. Pediatr Nephrol 31(4):641–650

    Article  Google Scholar 

  • Gulati A, Bagga A (2010) Large vessel vasculitis. Pediatr Nephrol 25(6):1037–1048

    Article  Google Scholar 

  • Hacklander T, Mertens H, Stattaus J, Lurken M, Lerch H, Altenburg A, Rautenbach J, Cramer BM (2004) Evaluation of renovascular hypertension: comparison of functional MRI and contrast-enhanced MRA with a routinely performed renal scintigraphy and DSA. J Comput Assist Tomogr 28(6):823–831

    Article  Google Scholar 

  • Hegde S, Coulthard MG (2007) Follow-up of early unilateral nephrectomy for hypertension. Arch Dis Child Fetal Neonatal Ed 92(4):F305–F306

    Article  Google Scholar 

  • Hiratzka LF, Bakris GL, Beckman JA, Bersin RM, Carr VF, Casey DE Jr, Eagle KA, Hermann LK, Isselbacher EM, Kazerooni EA, Kouchoukos NT, Lytle BW, Milewicz DM, Reich DL, Sen S, Shinn JA, Svensson LG, Williams DM (2010) ACCF/AHA/AATS/ACR/ASA/SCA/SCAI/SIR/STS/SVM guidelines for the diagnosis and management of patients with thoracic aortic disease. A report of the American College of Cardiology Foundation/American Heart Association Task Force On Practice Guidelines, American Association for Thoracic Surgery, American College of Radiology, American Stroke Association, Society of Cardiovascular Anesthesiologists, Society for Cardiovascular Angiography and Interventions, Society of Interventional Radiology, Society of Thoracic Surgeons, and Society for Vascular Medicine. J Am Coll Cardiol 55(14):e27–e129

    Article  Google Scholar 

  • Humbert J, Roussey-Kesler G, Guerin P, LeFrancois T, Connault J, Chenouard A, Warin-Fresse K, Salomon R, Bruel A, Allain-Launay E (2015) Diagnostic and medical strategy for renovascular hypertension: report from a monocentric pediatric cohort. Eur J Pediatr 174(1):23–32

    Article  CAS  Google Scholar 

  • Kadian-Dodov D, Gornik HL, Gu X, Froehlich J, Bacharach JM, Chi YW, Gray BH, Jaff MR, Kim ES, Mace P, Sharma A, Kline-Rogers E, White C, Olin JW (2016) Dissection and aneurysm in patients with fibromuscular dysplasia: findings from the U.S. registry for FMD. J Am Coll Cardiol 68(2):176–185

    Article  Google Scholar 

  • Karaconji T, Whist E, Jamieson RV, Flaherty MP, Grigg JRB (2019) Neurofibromatosis type 1: review and update on emerging therapies. Asia Pac J Ophtalmol (Phila) 8(1):62–72

    Google Scholar 

  • Kari JA, Roebuck DJ, McLaren CA, Davis M, Dillon MJ, Hamilton G, Shroff R, Marks SD, Tullus K (2014a) Angioplasty for renovascular hypertension in 78 children. Arch Dis Child 100:474–478

    Article  Google Scholar 

  • Kari J, Roebuck D, Tullus K (2014b) Renal artery stenosis in association with congenital anomalies of the kidney and urinary tract. Saudi Med J 35(10):1264–1266

    Google Scholar 

  • Kenny D, Polson JW, Martin RP, Paton JF, Wolf AR (2011) Hypertension and coarctation of the aorta: an inevitable consequence of developmental pathophysiology. Hypertens Res 34(5):543–547

    Article  Google Scholar 

  • Konig K, Gellermann J, Querfeld U, Schneider MB (2006) Treatment of severe renal artery stenosis by percutaneous transluminal renal angioplasty and stent implantation: review of the pediatric experience: apropos of two cases. Pediatr Nephrol 21(5):663–671

    Article  Google Scholar 

  • Lacombe M (2011) Surgical treatment of renovascular hypertension in children. Our J Vasc Endovasc Surg 41(6):770–777

    Article  CAS  Google Scholar 

  • Ladapo TA, Gajjar P, McCulloch M, Scott C, Numanoglu A, Nourse P (2015) Impact of revascularization on hypertension in children with Takayasu’s arteritis-induced renal artery stenosis: a 21-year review. Pediatr Nephrol 30(8):1289–1295

    Article  Google Scholar 

  • Lalji R, Tullus K (2018) What’s new in paediatric hypertension? Arch Dis Child 103(1):96–100. https://doi.org/10.1136/archdischild-2016-311662

  • Li JC, Wang L, Jiang YX, Dai Q, Cai S, Lv K, Qi ZH (2006) Evaluation of renal artery stenosis with velocity parameters of Doppler sonography. J Ultrasound Med 25(6):735–742

    Article  Google Scholar 

  • Marks SD, Gullett AM, Brennan E, Tullus K, Jaureguiberry G, Klootwijk E, Stanescu HC, Kleta R, Woolf AS (2011) Renal FMD may not confer a familial hypertensive risk nor is it caused by ACTA2 mutations. Pediatr Nephrol 26(10):1857–1861

    Article  Google Scholar 

  • McCrindle BW (1999) Coarctation of the aorta. Curr Opin Cardiol 14(5):448–452

    Article  CAS  Google Scholar 

  • McCulloch M, Andronikou S, Goddard E, Sinclair P, Lawrenson J, Mandelstam S, Beningfield SJ, Millar AJ (2003) Angiographic features of 26 children with Takayasu’s arteritis. Pediatr Radiol 33(4):230–235

    Article  Google Scholar 

  • McLaren CA, Roebuck DJ (2003) Interventional radiology for renovascular hypertension in children. Tech Vasc Interv Radiol 6(4):150–157

    Article  Google Scholar 

  • Miller JM, Rochitte CE, Dewey M, Arbab-Zadeh A, Niinuma H, Gottlieb I, Paul N, Clouse ME, Shapiro EP, Hoe J, Lardo AC, Bush DE, de Roos RA, Cox C, Brinker J, Lima JA (2008) Diagnostic performance of coronary angiography by 64-row CT. N Engl J Med 359(22):2324–2336

    Article  CAS  Google Scholar 

  • Min PK, Park S, Jung JH, Ko YG, Choi D, Jang Y, Shim WH (2005) Endovascular therapy combined with immunosuppressive treatment for occlusive arterial disease in patients with Takayasu’s arteritis. J Endovasc Ther 12(1):28–34

    Article  Google Scholar 

  • Minson S, McLaren CA, Roebuck DJ, Tullus K (2012) Infantile midaortic syndrome with aortic occlusion. Pediatr Nephrol 27(2):321–324

    Article  Google Scholar 

  • Moltzer E, Mattace Raso FU, Karamermer Y, Boersma E, Webb GD, Simoons ML, Danser AH, van den Meiracker AH, Roos-Hesselink JW (2010) Comparison of candesartan versus metoprolol for treatment of systemic hypertension after repaired aortic coarctation. Am J Cardiol 105(2):217–222

    Article  CAS  Google Scholar 

  • Mudalige N, Ranasinghe C, Stojanovic J (2021) The clinical and radiological cerebrovascular abnormalities associated with renovascular hypertension in children:a systematic review. Pediatr Nephrol 37(1):49–59

    Google Scholar 

  • O’Sullivan J (2014) Late hypertension in patients with repaired aortic coarctation. Curr Hypertens Rep 16(3):421

    Article  Google Scholar 

  • Olin JW, Sealove BA (2011) Diagnosis, management, and future developments of fibromuscular dysplasia. J Vasc Surg 53(3):826–836

    Article  Google Scholar 

  • Olin JW, Froehlich J, Gu X, Bacharach JM, Eagle K, Gray BH, Jaff MR, Kim ES, Mace P, Matsumoto AH, McBane RD, Kline-Rogers E, White CJ, Gornik HL (2012) The United States registry for fibromuscular dysplasia: results in the first 447 patients. Circulation 125(25):3182–3190

    Article  Google Scholar 

  • Olin JW, Gornik HL, Bacharach JM, Biller J, Fine LJ, Gray BH, Gray WA, Gupta R, Hamburg NM, Katzen BT, Lookstein RA, Lumsden AB, Newburger JW, Rundek T, Sperati CJ, Stanley JC (2014) Fibromuscular dysplasia: state of the science and critical unanswered questions: a scientific statement from the American Heart Association. Circulation 129(9):1048–1078

    Article  Google Scholar 

  • Ozen S, Ruperto N, Dillon MJ, Bagga A, Barron K, Davin JC, Kawasaki T, Lindsley C, Petty RE, Prieur AM, Ravelli A, Woo P (2006) EULAR/PReS endorsed consensus criteria for the classification of childhood vasculitides. Ann Rheum Dis 65(7):936–941

    Article  CAS  Google Scholar 

  • Ozen S, Pistorio A, Iusan SM, Bakkaloglu A, Herlin T, Brik R, Buoncompagni A, Lazar C, Bilge I, Uziel Y, Rigante D, Cantarini L, Hilario MO, Silva CA, Alegria M, Norambuena X, Belot A, Berkun Y, Estrella AI, Olivieri AN, Alpigiani MG, Rumba I, Sztajnbok F, Tambic-Bukovac L, Breda L, Al-Mayouf S, Mihaylova D, Chasnyk V, Sengler C, Klein-Gitelman M, Djeddi D, Nuno L, Pruunsild C, Brunner J, Kondi A, Pagava K, Pederzoli S, Martini A, Ruperto N (2010) EULAR/PRINTO/PRES criteria for Henoch-Schonlein purpura, childhood polyarteritis nodosa, childhood Wegener granulomatosis and childhood Takayasu arteritis: Ankara 2008. Part II: final classification criteria. Ann Rheum Dis 69(5):798–806

    Article  Google Scholar 

  • Palmerini T, Biondi-Zoccai G, Della RD, Stettler C, Sangiorgi D, D’Ascenzo F, Kimura T, Briguori C, Sabate M, Kim HS, De WA, Kedhi E, Smits PC, Kaiser C, Sardella G, Marullo A, Kirtane AJ, Leon MB, Stone GW (2012) Stent thrombosis with drug-eluting and bare-metal stents: evidence from a comprehensive network meta-analysis. Lancet 379(9824):1393–1402

    Article  CAS  Google Scholar 

  • Patel PA, Cahill AM (2021) Renovascular hypertension in children. CVIR Endovasc 4(1):10. https://doi.org/10.1186/s42155-020-00176-5

  • Patel P, Stojanovic J (2019) Diagnosis and treatment of renovascular disease in children. Semin Roentgenol 54(4):367–383. https://doi.org/10.1053/j.ro.2019.06.007

  • Pedersen TA, Munk K, Andersen NH, Lundorf E, Pedersen EB, Hjortdal VE, Emmertsen K (2011) High long-term morbidity in repaired aortic coarctation: weak association with residual arch obstruction. Congenit Heart Dis 6(6):573–582

    Article  Google Scholar 

  • Perdu J, Gimenez-Roqueplo AP, Boutouyrie P, Beaujour S, Laloux B, Nau V, Fiquet-Kempf B, Emmerich J, Tichet J, Plouin PF, Laurent S, Jeunemaitre X (2006) Alpha1-antitrypsin gene polymorphisms are not associated with renal arterial fibromuscular dysplasia. J Hypertens 24(4):705–710

    Article  CAS  Google Scholar 

  • Perdu J, Boutouyrie P, Bourgain C, Stern N, Laloux B, Bozec E, Azizi M, Bonaiti-Pellie C, Plouin PF, Laurent S, Gimenez-Roqueplo AP, Jeunemaitre X (2007) Inheritance of arterial lesions in renal fibromuscular dysplasia. J Hum Hypertens 21(5):393–400

    Article  CAS  Google Scholar 

  • Pober BR (2010) Williams-Beuren syndrome. N Engl J Med. 362 (3):239–252

    Google Scholar 

  • Poloskey SL, Kim ES, Sanghani R, Al-Quthami AH, Arscott P, Moran R, Rigelsky CM, Gornik HL (2012) Low yield of genetic testing for known vascular connective tissue disorders in patients with fibromuscular dysplasia. Vasc Med 17(6):371–378

    Article  Google Scholar 

  • Sandmann W, Dueppers P, Pourhassan S, Voiculescu A, Klee D, Balzer KM (2014) Early and long-term results after reconstructive surgery in 42 children and two young adults with renovascular hypertension due to fibromuscular dysplasia and middle aortic syndrome. Eur J Vasc Endovasc Surg 47(5):509–516

    Article  CAS  Google Scholar 

  • Sethna CB, Kaplan BS, Cahill AM, Velazquez OC, Meyers KE (2008) Idiopathic mid-aortic syndrome in children. Pediatr Nephrol 23(7):1135–1142

    Article  Google Scholar 

  • Seyahi E (2017) Takayasu arteritis:an update. Curr Opin Rheumatol 29(1):51–56

    Article  Google Scholar 

  • Shrinivasan A et al (2010) Angioplasty for renal artery stenosis in pediatric patients: an 11-year retrospective experience. J Vasc Interv Radiol 21(11):1672–80. https://doi.org/10.1016/j.jvir.2010.07.012

  • Shroff R, Roebuck DJ, Gordon I, Davies R, Stephens S, Marks S, Chan M, Barkovics M, McLaren CA, Shah V, Dillon MJ, Tullus K (2006) Angioplasty for renovascular hypertension in children: 20-year experience. Pediatrics 118(1):268–275

    Article  Google Scholar 

  • Slovut DP, Olin JW (2004) Fibromuscular dysplasia. N Engl J Med 350(18):1862–1871

    Article  CAS  Google Scholar 

  • Stadermann MB, Montini G, Hamilton G, Roebuck DJ, McLaren CA, Dillon MJ, Marks SD, Tullus K (2010) Results of surgical treatment for renovascular hypertension in children: 30 year single centre experience. Nephrol Dial Transplant 25(3):807–813

    Article  Google Scholar 

  • Stanley JC, Criado E, Upchurch GR Jr, Brophy PD, Cho KJ, Rectenwald JE, Kershaw DB, Williams DM, Berguer R, Henke PK, Wakefield TW (2006) Pediatric renovascular hypertension: 132 primary and 30 secondary operations in 97 children. J Vasc Surg 44(6):1219–1228

    Article  Google Scholar 

  • Tabbutt S, Nicolson SC, Adamson PC, Zhang X, Hoffman ML, Wells W, Backer CL, McGowan FX, Tweddell JS, Bokesch P, Schreiner M (2008) The safety, efficacy, and pharmacokinetics of esmolol for blood pressure control immediately after repair of coarctation of the aorta in infants and children: a multicenter, double-blind, randomized trial. J Thorac Cardiovasc Surg 136(2):321–328

    Article  CAS  Google Scholar 

  • Tanaka F, Kawakami A, Iwanaga N, Tamai M, Izumi Y, Aratake K, Arima K, Kamachi M, Nakamura H, Huang M, Ida H, Origuchi T, Eguchi K (2006) Infliximab is effective for Takayasu arteritis refractory to glucocorticoid and methotrexate. Intern Med 45(5):313–316

    Article  Google Scholar 

  • Towbin RB et al (2007) Cutting balloon angioplasty in children with resistant renal artery stenosis. J Vasc Interv Radiol 18(5):663–9. https://doi.org/10.1016/j.jvir.2007.02.014

  • Trautmann A, Roebuck D, McLaren C, Brennan E, Marks S, Tullus K (2017) Non-invasive imaging cannot replace formal angiography in the diagnosis of renovascular hypertension. Pediatr Nephrol 32(3):495–502

    Article  Google Scholar 

  • Tse Y, Marks SD, Brennan E, Hamilton G, McLaren CA, Roebuck DJ, Tullus K (2012) Renal artery revascularisation can restore kidney function with absent radiotracer uptake. Pediatr Nephrol 27(11):2153–2157

    Article  Google Scholar 

  • Tullus K (2013) Renovascular hypertension-is it fibromuscular dysplasia or Takayasu arteritis. Pediatr Nephrol 28(2):191–196

    Article  Google Scholar 

  • Tullus K (2015) Management of the renovascular disease in children with Takayasu arteritis. Pediatr Nephrol 30(8):1213–1216

    Article  Google Scholar 

  • Tullus K (2018) Renovascular hypertension in small children-is it Takayasu arteritis of fibromuscular dysplasia? J Am Soc Hypertens 12(7):506–508

    Google Scholar 

  • Tullus K, Brennan E, Hamilton G, Lord R, McLaren CA, Marks SD, Roebuck DJ (2008) Renovascular hypertension in children. Lancet 371(9622):1453–1463

    Article  CAS  Google Scholar 

  • Tullus K, Roebuck DJ, McLaren CA, Marks SD (2010) Imaging in the evaluation of renovascular disease. Pediatr Nephrol 25(6):1049–1056

    Article  Google Scholar 

  • Twite MD, Stenquist S, Ing RJ (2019) Williams syndrome. Paediatr Anaesth 29(5):483–490

    Article  Google Scholar 

  • Tyagi S, Kaul U, Satsangi D, Arora R (1997) Percutaneous transluminal angioplasty for renovascular hypertension in children: initial and long-term results. Pediatrics 99(1):44–49

    Article  CAS  Google Scholar 

  • Vasbinder GB, Nelemans PJ, Kessels AG, Kroon AA, Maki JH, Leiner T, Beek FJ, Korst MB, Flobbe K, de Haan MW, van Zwam WH, Postma CT, Hunink MG, de Leeuw PW, van Engelshoven JM (2004) Accuracy of computed tomographic angiography and magnetic resonance angiography for diagnosing renal artery stenosis. Ann Intern Med 141(9):674–682

    Article  Google Scholar 

  • Viering DHHM, Chan MMY, Hoogenboom L, Iancu D, de Baaij JHF, Tullus K, Kleta R, Bockenhauer D (2020) Genetics of renovascular hypertension in children. J Hypertens 38(10):1964–1970

    Article  CAS  Google Scholar 

  • Vo NJ, Hammelman BD, Racadio JM, Strife CF, Johnson ND, Racadio JM (2006) Anatomic distribution of renal artery stenosis in children: implications for imaging. Pediatr Radiol 36(10):1032–1036

    Article  Google Scholar 

  • Walhout RJ, Plokker HW, Meijboom EJ, Doevendans PA (2008) Advances in the management and surveillance of patients with aortic coarctation. Acta Cardiol 63(6):771–782

    Article  Google Scholar 

  • Warthol-Celinska E, Berrandou T, Prjbisz A, Georges A, Dupre D, Januszewicz M, Florczak E, Jozwik-Plebanek K, Dobrowolski P, Åšmigielskie W, Drygas W, Kadziela J, Witkowski A, Kabat M, Szczerbo-Trojanowska M, Pappacocogli M, Persu A, Jeunemaitre X, Januszewicz A, Boutia-Naji N (2020) Genetic study of PHACTR1 and fibromuscular dysplasia, meta-analysis and effects on clinical features of patients the ARCADIA-POL study. Hypertension 76:e4–e7

    Google Scholar 

  • Wong H, Hadi M, Khoury T, Geary D, Rubin B, Filler G (2006) Management of severe hypertension in a child with tuberous sclerosis-related major vascular abnormalities. J Hypertens 24(3):597–599

    Article  CAS  Google Scholar 

  • Wong D, Benson LN, Van Arsdell GS, Karamlou T, McCrindle BW (2008) Balloon angioplasty is preferred to surgery for aortic coarctation. Cardiol Young 18(1):79–88

    Article  Google Scholar 

  • Ye C, Yin H, Lin Y, Zhou L, Ye R, Li X, Han A, Wang S (2012) Abdominal aorta aneurysms in children: single-center experience of six patients. Ann Thorac Surg 93(1):201–205

    Article  Google Scholar 

  • Zhu G, He F, Gu Y, Yu H, Chen B, Hu Z, Liang W, Wang Z (2014) Angioplasty for pediatric renovascular hypertension:1 13 year experience. Diagn Interv Radiol 20(3):285–292

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Great Ormond Street Hospital for Children, London, UK

    Kjell Tullus & Jelena Stojanovic

Authors
  1. Kjell Tullus
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Jelena Stojanovic
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Kjell Tullus .

Editor information

Editors and Affiliations

  1. Department of Pediatrics, University of Washington School of Medicine, Seattle, WA, USA

    Joseph T. Flynn

  2. Pediatric Nephrology Unit, Mass General for Children at MGB Harvard Medical School, Boston, MA, USA

    Julie R. Ingelfinger

  3. Department of Pediatrics Division of Pediatric Nephrology, Johns Hopkins University School of Medicine, Baltimore, MD, USA

    Tammy M. Brady

Section Editor information

  1. University of Washington School of Medicine, Seattle, WA, USA

    Joseph T. Flynn MD, MS

  2. Divison of Nephrology, Seattle Children’s Hospital, Seattle, WA, USA

    Joseph T. Flynn MD, MS

Rights and permissions

Reprints and permissions

Copyright information

© 2023 Springer Nature Switzerland AG

About this entry

Check for updates. Verify currency and authenticity via CrossMark

Cite this entry

Tullus, K., Stojanovic, J. (2023). Renovascular Hypertension, Vasculitis, and Aortic Coarctation. In: Flynn, J.T., Ingelfinger, J.R., Brady, T.M. (eds) Pediatric Hypertension. Springer, Cham. https://doi.org/10.1007/978-3-031-06231-5_24

Download citation

  • DOI: https://doi.org/10.1007/978-3-031-06231-5_24

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-031-06230-8

  • Online ISBN: 978-3-031-06231-5

  • eBook Packages: MedicineReference Module Medicine

Publish with us

Policies and ethics

Search

Navigation