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Enhancing Cognition in People with Mental Health Vulnerabilities

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Prevention in Mental Health

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Abstract

Cognitive alterations are core features of psychotic disorders and severe psychiatric conditions significantly affecting patients’ quality of life and socio-occupational outcomes. Considering that these alterations respond only mildly to pharmacological interventions, in the last 30 years research has focused on the development of behavioural interventions such as cognitive remediation or cognitive-enhancing programs. The beneficial effects of these interventions on chronic patients suffering from schizophrenia are well established as these interventions act on several cognitive domains including working memory, attention and executive functioning. However, less is known about their effects on patients at risk or in the first phases of psychosis and about their exact effects on several brain indices including grey matter volumes, white matter integrity or blood oxygenation level-dependent activations.

Therefore, in this chapter we summarized current evidence present in the literature about the effects of these interventions on patients in the chronic, early and prodromal phases of schizophrenia and related disorders. Results suggest that cognitive remediation and similar approaches exert a beneficial effect on several cognitive functions in patients suffering from schizophrenia and related psychotic disorders and on individuals at risk of developing these conditions. We suggest that the early the intervention, the better and more durable the beneficial outcomes. We also suggest the necessity of combining different types of interventions as cognitive-enhancing interventions alone do not seem to affect social cognition or social skills deficit characteristic of psychosis.

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Acknowledgements

This study was partially supported by grants from the Ministry of Health GR-2016-02361283 (CP).

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Authors and Affiliations

  1. Department of Neurosciences, Biomedicine and Movement Sciences, Section of Psychiatry, University of Verona, Verona, Italy

    Marcella Bellani & Niccolò Zovetti

  2. Department of Neurosciences, Biomedicine and Movement Sciences, Section of Clinical Psychology, University of Verona, Verona, Italy

    Cinzia Perlini

  3. Department of Neurosciences and Mental Health, Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Milan, Italy

    Paolo Brambilla

  4. Department of Pathophysiology and Transplantation, University of Milan, Milan, Italy

    Paolo Brambilla

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  1. Marcella Bellani
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  2. Niccolò Zovetti
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  3. Cinzia Perlini
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  4. Paolo Brambilla
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Correspondence to Marcella Bellani .

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Editors and Affiliations

  1. Department of Medicine (DAME), University of Udine, Udine, Italy

    Marco Colizzi

  2. Department of Neurosciences, Biomedicine and Movement Sciences, University of Verona, Verona, Italy

    Mirella Ruggeri

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Bellani, M., Zovetti, N., Perlini, C., Brambilla, P. (2022). Enhancing Cognition in People with Mental Health Vulnerabilities. In: Colizzi, M., Ruggeri, M. (eds) Prevention in Mental Health . Springer, Cham. https://doi.org/10.1007/978-3-030-97906-5_12

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