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Intrathecal Pump Management

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Intrathecal Pump Drug Delivery

Part of the book series: Medical Radiology ((Med Radiol Diagn Imaging))

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Abstract

Intrathecal therapy was introduced in the 1980s. Since that time, it has evolved into a very beneficial therapy for chronic pain, cancer pain, and spasticity. Patients are considered optimal candidates for intrathecal therapy when conservative treatments have been ineffective or when patients have intolerable side effects from systemic medications. By delivering medication directly to the intrathecal space, profound analgesia can be achieved with far fewer side effects. This also applies to patients suffering from spasticity that respond poorly to oral medications. This chapter will highlight proper patient selection, intrathecal dosing, medication compounding, and training requirements for implanting and managing physicians and will provide strategies to optimize the sustainability of intrathecal opioid therapy.

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Abbreviations

CT:

Computed tomography

CYP:

Cytochrome P450

FDA:

Food and Drug Administration

IDDS:

Intrathecal drug delivery system

ITB:

Intrathecal baclofen

MRI:

Magnetic resonance imaging

OIH:

Opioid-induced hyperalgesia

PTC:

Patient therapy controller

PTM:

Patient therapy manager

TDD:

Targeted drug delivery

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Author information

Authors and Affiliations

  1. Crimson Pain Management, Overland Park, KS, USA

    Daniel R. Kloster

Authors
  1. Daniel R. Kloster
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Editor information

Editors and Affiliations

  1. Comprehensive Specialty Care, Edmond, OK, USA

    Douglas P. Beall

  2. Department of Radiology, Vancouver General Hospital, Vancouver, BC, Canada

    Peter L. Munk

  3. Virginia iSpine Physicians, PC, Richmond, VA, USA

    Michael J. DePalma

  4. Source Healthcare, Santa Monica, CA, USA

    Timothy Davis

  5. IPM Medical Group, Inc., Walnut Creek, CA, USA

    Kasra Amirdelfan

  6. Ainsworth Institute of Pain Management, New York, NY, USA

    Corey W. Hunter

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Kloster, D.R. (2022). Intrathecal Pump Management. In: Beall, D.P., Munk, P.L., DePalma, M.J., Davis, T., Amirdelfan, K., Hunter, C.W. (eds) Intrathecal Pump Drug Delivery. Medical Radiology(). Springer, Cham. https://doi.org/10.1007/978-3-030-86244-2_7

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  • DOI: https://doi.org/10.1007/978-3-030-86244-2_7

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-86243-5

  • Online ISBN: 978-3-030-86244-2

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