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Intrathecal Drug Delivery

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Spine Pain Care

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Abstract

This chapter is to introduce the use of an intrathecal drug delivery system for the management of refractory chronic cancer or noncancer pain. The chapter begins with an overview as to how intrathecal therapy can be a useful modality to modulate spinal transmission of pain (nociceptive) signals, followed by historical perspectives, indications, contraindications of intrathecal therapy, and current guidelines from the Polyanalgesic Consensus Conference (PACC). The chapter introduces the relevant surgical techniques, complications, and troubleshooting and concludes with a summary of the use of intrathecal therapy and future advancements in developing new pump technology, catheter materials, and intrathecal drugs for the treatment of severe chronic pain.

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Authors and Affiliations

  1. Department of Pain Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA

    Saiyun Hou & Salahadin Abdi

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  1. Saiyun Hou
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  2. Salahadin Abdi
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Correspondence to Salahadin Abdi .

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Editors and Affiliations

  1. Richard J. Kitz Professor of Anesthesia Research Harvard Medical School, Harvard University, Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Boston, MA, USA

    Jianren Mao

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Hou, S., Abdi, S. (2020). Intrathecal Drug Delivery. In: Mao, J. (eds) Spine Pain Care. Springer, Cham. https://doi.org/10.1007/978-3-030-27447-4_25

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  • DOI: https://doi.org/10.1007/978-3-030-27447-4_25

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-27446-7

  • Online ISBN: 978-3-030-27447-4

  • eBook Packages: MedicineMedicine (R0)

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