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Multiple Pregnancies

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Benirschke's Pathology of the Human Placenta

Abstract

This chapter examines the pathology of multigestational placentas. Although this includes a brief discussion on the zygosity and genetics of twinning, the majority of the chapter is focused on the placental anatomy of twin gestation. This includes the relationship between zygosity and placental formation, including monoamniotic, monochorionic, diamniotic, and dichorionic placentas, and techniques on recognizing the type of placentation. A special focus is made of vascular anatomy, particularly as pertaining to twin-twin transfusion syndrome. In addition, the more unusual fetal results of twinning, including acardiac twins, conjoined twins, and congenital anomalies, are briefly discussed. Finally, the chapter closes with a discussion of the morbidity and mortality associated with twin gestation.

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  1. Jefferson University Hospital, Pathology, Anatomy, and Cell Biology, Philadelphia, PA, USA

    Joanna Sue Yee Chan

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  1. Professor of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York Presbyterian Hospital, New York, NY, USA

    Rebecca N. Baergen

  2. Centre for Trophoblast Research, University of Cambridge, Cambridge, UK

    Graham J. Burton

  3. Professor Emeritus of Pathology, State University of New York, Stony Brook, NY, USA

    Cynthia G. Kaplan

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Chan, J.S.Y. (2022). Multiple Pregnancies. In: Baergen, R.N., Burton, G.J., Kaplan, C.G. (eds) Benirschke's Pathology of the Human Placenta. Springer, Cham. https://doi.org/10.1007/978-3-030-84725-8_18

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