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The Genus Phoma: A Review of Its Potential Bioactivities, Implications, and Prospects

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Phoma: Diversity, Taxonomy, Bioactivities, and Nanotechnology

Abstract

This chapter presents a constructive review of genus Phoma, which includes important plant endophytes, plant pathogens, and in a few cases, pathogens of human and other vertebrates. Furthermore, many Phoma lineages have been reported to be efficient in biological control and to exhibit promising characteristics for agricultural, medical, and other industry field. The chapter includes many species and their useful beneficial traits, including microbial bioactive compounds that could be incorporated into biotechnology. Metabolites of Phoma have been demonstrated to promote crop protection, with great potential for biological weed control, in addition to exhibiting important biological factors and pharmacological properties such as anticancer, antimicrobial, and antioxidant activities. Alternative control products are scarcely available in the market for some Phoma species. However, there is a need for gathering information to highlight the great biotechnological potential to be explored. Therefore, the aim of this work is to describe the literature concerning the biological activities of the genus Phoma.

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Abbreviations

A549:

Human lung cancer

CHL:

Chinese hamster lung

CNS:

Central nervous system

DV3:

Dengue virus type 3

EPS:

Exopolysaccharides

H1N1:

Influenza A virus

HCT15:

Human colon cancer

HeLa:

Human cervical carcinoma

HIV-1:

Human immunodeficiency virus type 1

HL-60:

Leukemia cell line

HT-29:

Colon cancer cells

L-O2 cells:

Human hepatocytes

MCF-7:

Breast cancer cells

MGC80-3:

Gastric carcinoma cells

P-388:

Leukemia cell line

RSV:

Respiratory syncytial virus

SK-MEL-2:

Human skin cancer

SK-OV-3:

Human ovarian cancer

SMMC-772:

Liver cancer cells

TeA:

Tenuazonic acid

XF 498:

Human CNS cancer

YCP:

Yancheng polysaccharide

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  1. Department of Chemical Engineering, Federal University of Santa Maria, Santa Maria, Brazil

    Luciana Luft, Tássia C. Confortin, Izelmar Todero & Marcio A. Mazutti

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  2. Tássia C. Confortin
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  1. Department of Biotechnology, SGB Amravati University, Amravati, Maharashtra, India

    Mahendra Rai

  2. Department of Plant Protection Institute of Plant Pathology and Mycology, University of Life Sciences in Lublin Lublin, Lubelskie, Poland

    Beata Zimowska

  3. Plant Protection Institute, University of Debrecen, Debrecen, Hungary

    György János Kövics

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Luft, L., Confortin, T.C., Todero, I., Mazutti, M.A. (2022). The Genus Phoma: A Review of Its Potential Bioactivities, Implications, and Prospects. In: Rai, M., Zimowska, B., Kövics, G.J. (eds) Phoma: Diversity, Taxonomy, Bioactivities, and Nanotechnology. Springer, Cham. https://doi.org/10.1007/978-3-030-81218-8_12

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