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The Role of Physical Activity in Sarcopenia

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Sarcopenia

Part of the book series: Practical Issues in Geriatrics ((PIG))

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Abstract

Sarcopenia is a geriatric syndrome that can lead to mortality and morbidity. Physical activity is a cornerstone in human health, for all ages and most health conditions including sarcopenia. There is evidence of the role of physical activity interventions to prevent and manage sarcopenia. General physical activity guidelines for the older population can be followed in the prescription of physical activity for sarcopenia. While emphasis of resistance exercise is meaningful due to the fact that low muscle mass is the first marker of sarcopenia, combined aerobic and resistance exercise can yield greater benefits than separate aerobic and resistance exercise per se. Sedentary behaviour increases with age and is associated with increases in fat mass and decreases in muscle mass potentially leading to sarcopenic obesity. Combined aerobic and resistance exercise can help to prevent and manage sarcopenic obesity which are two combined risk challenges that the older population usually face. Eccentric resistance exercise is a suggested modality for sarcopenic individuals. Moreover, neuromotor exercise is important to prevent falls and stiffness. Low extremities are the most vulnerable parts of the human body that can be affected by sarcopenia and may cause falls and fractures. Long-term engagement in Tai Chi activities is a recommended neuromotor exercise that can help to improve balance, strength, and posture of the low extremities. While the current chapter emphasis some types of physical activities in order to prevent and manage sarcopenia, there is a need for a consensus of physical activity guidelines for sarcopenia.

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References

  1. Caspersen CJ, Powell KE, Christenson GM. Physical activity, exercise, and physical fitness: definitions and distinctions for health-related research. Public Health Rep. 1985;100(2):126–31.

    CAS  PubMed  PubMed Central  Google Scholar 

  2. Jette M, Sidney K, Blumchen G. Metabolic equivalents (METS) in exercise testing, exercise prescription, and evaluation of functional capacity. Clin Cardiol. 1990;13(8):555–65. https://doi.org/10.1002/clc.4960130809.

    Article  CAS  PubMed  Google Scholar 

  3. Smith L, Ekelund U, Hamer M. The potential yield of non-exercise physical activity energy expenditure in public health. Sports Med (Auckland, NZ). 2015;45(4):449–52. https://doi.org/10.1007/s40279-015-0310-2.

    Article  Google Scholar 

  4. Sheikholeslami S, Ghanbarian A, Azizi F. The impact of physical activity on non-communicable diseases: findings from 20 years of the Tehran Lipid and Glucose Study. Int J Endocrinol Metab. 2018;16(4 Suppl):e84740-e. https://doi.org/10.5812/ijem.84740.

    Article  Google Scholar 

  5. Health H. Exercise is an all-natural treatment to fight depression. Cambridge, MA: Harvard Health Publishing, Harvard University; 2013. https://www.health.harvard.edu/mind-and-mood/exercise-is-an-all-natural-treatment-to-fight-depression. Accessed 9 Mar 2020.

    Google Scholar 

  6. Woo J. Sarcopenia. Clin Geriatr Med. 2017;33(3):305–14. https://doi.org/10.1016/j.cger.2017.02.003.

    Article  PubMed  Google Scholar 

  7. Mayhew AJ, Amog K, Phillips S, Parise G, McNicholas PD, de Souza RJ, et al. The prevalence of sarcopenia in community-dwelling older adults, an exploration of differences between studies and within definitions: a systematic review and meta-analyses. Age Ageing. 2019;48(1):48–56. https://doi.org/10.1093/ageing/afy106.

    Article  CAS  PubMed  Google Scholar 

  8. Lee S-Y, Tung H-H, Liu C-Y, Chen L-K. Physical activity and sarcopenia in the geriatric population: a systematic review. J Am Med Dir Assoc. 2018;19(5):378–83. https://doi.org/10.1016/j.jamda.2018.02.003.

    Article  PubMed  Google Scholar 

  9. Beaudart C, Dawson A, Shaw SC, Harvey NC, Kanis JA, Binkley N, et al. Nutrition and physical activity in the prevention and treatment of sarcopenia: systematic review. Osteoporos Int. 2017;28(6):1817–33. https://doi.org/10.1007/s00198-017-3980-9.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  10. Miyazaki R, Takeshima T, Kotani K. Exercise intervention for anti-sarcopenia in community-dwelling older people. J Clin Med Res. 2016;8(12):848–53. https://doi.org/10.14740/jocmr2767w.

    Article  PubMed  PubMed Central  Google Scholar 

  11. Marzetti E, Calvani R, Tosato M, Cesari M, Di Bari M, Cherubini A, et al. Physical activity and exercise as countermeasures to physical frailty and sarcopenia. Aging Clin Exp Res. 2017;29(1):35–42. https://doi.org/10.1007/s40520-016-0705-4.

    Article  PubMed  Google Scholar 

  12. Short KR, Vittone JL, Bigelow ML, Proctor DN, Nair KS. Age and aerobic exercise training effects on whole body and muscle protein metabolism. Am J Physiol Endocrinol Metab. 2004;286(1):E92–101. https://doi.org/10.1152/ajpendo.00366.2003.

    Article  CAS  PubMed  Google Scholar 

  13. Laurin JL, Reid JJ, Lawrence MM, Miller BF. Long-term aerobic exercise preserves muscle mass and function with age. Curr Opin Physio. 2019;10:70–4. https://doi.org/10.1016/j.cophys.2019.04.019.

    Article  Google Scholar 

  14. Lira VA, Okutsu M, Zhang M, Greene NP, Laker RC, Breen DS, et al. Autophagy is required for exercise training-induced skeletal muscle adaptation and improvement of physical performance. FASEB J. 2013;27(10):4184–93.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  15. Harber MP, Konopka AR, Undem MK, Hinkley JM, Minchev K, Kaminsky LA, et al. Aerobic exercise training induces skeletal muscle hypertrophy and age-dependent adaptations in myofiber function in young and older men. J Appl Physiol (1985). 2012;113(9):1495–504. https://doi.org/10.1152/japplphysiol.00786.2012.

    Article  PubMed Central  Google Scholar 

  16. Law TD, Clark LA, Clark BC. Resistance exercise to prevent and manage sarcopenia and Dynapenia. Annu Rev Gerontol Geriatr. 2016;36(1):205–28. https://doi.org/10.1891/0198-8794.36.205.

    Article  PubMed  PubMed Central  Google Scholar 

  17. Johnston AP, De Lisio M, Parise G. Resistance training, sarcopenia, and the mitochondrial theory of aging. Appl Physiol Nutr Metab. 2008;33(1):191–9. https://doi.org/10.1139/h07-141.

    Article  CAS  PubMed  Google Scholar 

  18. Yoo S-Z, No M-H, Heo J-W, Park D-H, Kang J-H, Kim SH, et al. Role of exercise in age-related sarcopenia. J Exerc Rehabil. 2018;14(4):551–8. https://doi.org/10.12965/jer.1836268.134.

    Article  PubMed  PubMed Central  Google Scholar 

  19. Liu C-J, Latham N. Can progressive resistance strength training reduce physical disability in older adults? A meta-analysis study. Disabil Rehabil. 2011;33(2):87–97. https://doi.org/10.3109/09638288.2010.487145.

    Article  PubMed  Google Scholar 

  20. Hassan BH, Hewitt J, Keogh JWL, Bermeo S, Duque G, Henwood TR. Impact of resistance training on sarcopenia in nursing care facilities: a pilot study. Geriatr Nurs. 2016;37(2):116–21. https://doi.org/10.1016/j.gerinurse.2015.11.001.

    Article  PubMed  Google Scholar 

  21. Vandervoort AA. Aging of the human neuromuscular system. Muscle Nerve. 2002;25(1):17–25. https://doi.org/10.1002/mus.1215.

    Article  CAS  PubMed  Google Scholar 

  22. Vallejo AF, Schroeder ET, Zheng L, Jensky NE, Sattler FR. Cardiopulmonary responses to eccentric and concentric resistance exercise in older adults. Age Ageing. 2006;35(3):291–7. https://doi.org/10.1093/ageing/afj082.

    Article  PubMed  Google Scholar 

  23. Mueller M, Breil FA, Vogt M, Steiner R, Lippuner K, Popp A, et al. Different response to eccentric and concentric training in older men and women. Eur J Appl Physiol. 2009;107(2):145–53. https://doi.org/10.1007/s00421-009-1108-4.

    Article  PubMed  Google Scholar 

  24. Lim J-Y. Therapeutic potential of eccentric exercises for age-related muscle atrophy. Integr Med Res. 2016;5(3):176–81.

    Article  PubMed  PubMed Central  Google Scholar 

  25. Hamada K, Vannier E, Sacheck JM, Witsell AL, Roubenoff R. Senescence of human skeletal muscle impairs the local inflammatory cytokine response to acute eccentric exercise. FASEB J. 2005;19(2):264–6. https://doi.org/10.1096/fj.03-1286fje.

    Article  CAS  PubMed  Google Scholar 

  26. Tajra V, Tibana RA, Vieira DCL, de Farias DL, Teixeira TG, Funghetto SS, et al. Identification of high responders for interleukin-6 and creatine kinase following acute eccentric resistance exercise in elderly obese women. J Sci Med Sport. 2014;17(6):662–6. https://doi.org/10.1016/j.jsams.2013.09.012.

    Article  PubMed  Google Scholar 

  27. Reeves ND, Maganaris CN, Longo S, Narici MV. Differential adaptations to eccentric versus conventional resistance training in older humans. Exp Physiol. 2009;94(7):825–33. https://doi.org/10.1113/expphysiol.2009.046599.

    Article  PubMed  Google Scholar 

  28. Roubenoff R. Sarcopenic obesity: the confluence of two epidemics. Obes Res. 2004;12(6):887–8. https://doi.org/10.1038/oby.2004.107.

    Article  PubMed  Google Scholar 

  29. Polyzos SA, Margioris AN. Sarcopenic obesity. Hormones. 2018;17(3):321–31. https://doi.org/10.1007/s42000-018-0049-x.

    Article  PubMed  Google Scholar 

  30. Dieli-Conwright CM, Courneya KS, Demark-Wahnefried W, Sami N, Lee K, Buchanan TA, et al. Effects of aerobic and resistance exercise on metabolic syndrome, sarcopenic obesity, and circulating biomarkers in overweight or obese survivors of breast cancer: a randomized controlled trial. J Clin Oncol. 2018;36(9):875–83. https://doi.org/10.1200/JCO.2017.75.7526.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  31. Villareal DT, Aguirre L, Gurney AB, Waters DL, Sinacore DR, Colombo E, et al. Aerobic or resistance exercise, or both, in dieting obese older adults. N Engl J Med. 2017;376(20):1943–55.

    Article  PubMed  PubMed Central  Google Scholar 

  32. Kim D-I, Lee DH, Hong S, Jo S-W, Won Y-S, Jeon JY. Six weeks of combined aerobic and resistance exercise using outdoor exercise machines improves fitness, insulin resistance, and chemerin in the Korean elderly: a pilot randomized controlled trial. Arch Gerontol Geriatr. 2018;75:59–64. https://doi.org/10.1016/j.archger.2017.11.006.

    Article  PubMed  Google Scholar 

  33. Shiotsu Y, Yanagita M. Intervention study on the exercise order of combined aerobic & resistance training in the elderly. J Sports Sci. 2017;5:322–31.

    Google Scholar 

  34. Shiotsu Y, Yanagita M. Comparisons of low-intensity versus moderate-intensity combined aerobic and resistance training on body composition, muscle strength, and functional performance in older women. Menopause. 2018;25(6):668–75. https://doi.org/10.1097/gme.0000000000001060.

    Article  PubMed  Google Scholar 

  35. Porter MM. The effects of strength training on sarcopenia. Can J Appl Physiol. 2001;26(1):123–41. https://doi.org/10.1139/h01-009.

    Article  CAS  PubMed  Google Scholar 

  36. Waters DL, Hale L, Grant AM, Herbison P, Goulding A. Osteoporosis and gait and balance disturbances in older sarcopenic obese new Zealanders. Osteoporos Int. 2010;21(2):351–7. https://doi.org/10.1007/s00198-009-0947-5.

    Article  CAS  PubMed  Google Scholar 

  37. Lam P. Tai Chi for Health Institute. Australia. 2018. https://taichiforhealthinstitute.org/what-is-tai-chi/. Accessed 8 Mar 2020.

  38. Wu G. Evaluation of the effectiveness of tai chi for improving balance and preventing falls in the older population—a review. J Am Geriatr Soc. 2002;50(4):746–54. https://doi.org/10.1046/j.1532-5415.2002.50173.x.

    Article  PubMed  Google Scholar 

  39. Zhou M, Peng N, Dai Q, Li H-W, Shi R-G, Huang W. Effect of tai chi on muscle strength of the lower extremities in the elderly. Chin J Integr Med. 2016;22(11):861–6. https://doi.org/10.1007/s11655-015-2104-7.

    Article  PubMed  Google Scholar 

  40. Wu G, Zhao F, Zhou X, Wei L. Improvement of isokinetic knee extensor strength and reduction of postural sway in the elderly from long-term tai chi exercise. Arch Phys Med Rehabil. 2002;83(10):1364–9. https://doi.org/10.1053/apmr.2002.34596.

    Article  PubMed  Google Scholar 

  41. Li JX, Xu DQ, Hong Y. Changes in muscle strength, endurance, and reaction of the lower extremities with tai chi intervention. J Biomech. 2009;42(8):967–71. https://doi.org/10.1016/j.jbiomech.2009.03.001.

    Article  PubMed  Google Scholar 

  42. Woo J, Hong A, Lau E, Lynn H. A randomised controlled trial of tai chi and resistance exercise on bone health, muscle strength and balance in community-living elderly people. Age Ageing. 2007;36(3):262–8. https://doi.org/10.1093/ageing/afm005.

    Article  PubMed  Google Scholar 

  43. Qi M, Moyle W, Jones C, Weeks B. Tai chi combined with resistance training for adults aged 50 years and older: a systematic review. J Geriatr Phys Ther. 2020;43(1):32–41. https://doi.org/10.1519/jpt.0000000000000218.

    Article  PubMed  Google Scholar 

  44. Zou L, Han J, Li C, Yeung AS, Hui SS, Tsang WWN, et al. Effects of Tai Chi on lower limb proprioception in adults aged over 55: a systematic review and meta-analysis. Arch Phys Med Rehabil. 2019;100(6):1102–13. https://doi.org/10.1016/j.apmr.2018.07.425.

    Article  PubMed  Google Scholar 

  45. Leung PM, Ejupi A, van Schooten KS, Aziz O, Feldman F, Mackey DC, et al. Association between sedentary behaviour and physical, cognitive, and psychosocial status among older adults in assisted living. Biomed Res Int. 2017;2017:9160504. https://doi.org/10.1155/2017/9160504.

    Article  PubMed  PubMed Central  Google Scholar 

  46. Aggio DA, Sartini C, Papacosta O, Lennon LT, Ash S, Whincup PH, et al. Cross-sectional associations of objectively measured physical activity and sedentary time with sarcopenia and sarcopenic obesity in older men. Prev Med. 2016;91:264–72. https://doi.org/10.1016/j.ypmed.2016.08.040.

    Article  PubMed  PubMed Central  Google Scholar 

  47. Gianoudis J, Bailey CA, Daly RM. Associations between sedentary behaviour and body composition, muscle function and sarcopenia in community-dwelling older adults. Osteoporos Int. 2015;26(2):571–9. https://doi.org/10.1007/s00198-014-2895-y.

    Article  CAS  PubMed  Google Scholar 

  48. Smith L, Thomas EL, Bell JD, Hamer M. The association between objectively measured sitting and standing with body composition: a pilot study using MRI. BMJ Open. 2014;4(6):e005476. https://doi.org/10.1136/bmjopen-2014-005476.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  49. Peake J, Gatta PD, Cameron-Smith D. Aging and its effects on inflammation in skeletal muscle at rest and following exercise-induced muscle injury. Am J Physiol Regul Integr Comp Physiol. 2010;298(6):R1485–R95. https://doi.org/10.1152/ajpregu.00467.2009.

    Article  CAS  PubMed  Google Scholar 

  50. Dalle S, Rossmeislova L, Koppo K. The role of inflammation in age-related sarcopenia. Front Physiol. 2017;8:1045. https://doi.org/10.3389/fphys.2017.01045.

    Article  PubMed  PubMed Central  Google Scholar 

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Smith, L., Alkahtani, S. (2021). The Role of Physical Activity in Sarcopenia. In: Veronese, N., Beaudart, C., Sabico, S. (eds) Sarcopenia. Practical Issues in Geriatrics. Springer, Cham. https://doi.org/10.1007/978-3-030-80038-3_12

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