Abstract
In recent years, 3D segmentation of the pancreas has received a lot of attention from researchers because of its importance for clinical diagnosis and treatment. However, there are many problems with 3D pancreatic segmentation: 1) because the shape of the pancreas is not regular enough compared to other organs in the abdomen, it has a relatively small shape and there is also an excessive background of interference, resulting in inaccurate segmentation results for the pancreas; 2) one of the main drawbacks of 3D convolutional neural networks for segmentation is the excessive memory occupation, which requires censoring of the network structure to fit a given memory budget. To address the above issues, this paper proposes a new coarse-to-fine method based on convolutional neural networks (CNNs). In the first stage, the segmentation is trained to obtain candidate regions. In the second stage, the approximate location of the pancreas is obtained after the first stage, and then the pancreas is finely segmented in this approximate location. The convolutional neural network used in this paper is a modified 3DUnet network, which is improved to require less memory and higher segmentation accuracy compared to the traditional 3DUnet network. This segmentation method requires a less demanding experimental environment than other algorithms, and can also improve accuracy by eliminating a large amount of irrelevant background interference. The combination of our proposed network structure and the two-stage segmentation method achieves advanced performance.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Roth, H.R., et al.: DeepOrgan: multi-level deep convolutional networks for automated pancreas segmentation. In: Navab, N., Hornegger, J., Wells, W.M., Frangi, A.F. (eds.) MICCAI 2015. LNCS, vol. 9349, pp. 556–564. Springer, Cham (2015). https://doi.org/10.1007/978-3-319-24553-9_68
Isensee, F., Petersen, J., Kohl, S.A.A, et al.: Nnu-net: breaking the spell on successful medical image segmentation (2019)
Roth, H.R., Oda, H., Zhou, X., et al.: An application of cascaded 3D fully convolutional networks for medical image segmentation. Comput. Med. Imaging Graph. Off. J. Comput. Med. Imaging Soc. 66, 90 (2018)
Milletari, F., Navab, N., Ahmadi, S.A.: V-net: Fully convolutional neural networks for volumetric medical image segmentation. In: 2016 Fourth International Conference on 3D Vision (3DV), pp. 565–571 (2016)
Çiçek, Ö., Abdulkadir, A., Lienkamp, S.S., Brox, T., Ronneberger, O.: 3D U-Net: learning dense volumetric segmentation from sparse annotation. In: Ourselin, S., Joskowicz, L., Sabuncu, M.R., Unal, G., Wells, W. (eds.) MICCAI 2016. LNCS, vol. 9901, pp. 424–432. Springer, Cham (2016). https://doi.org/10.1007/978-3-319-46723-8_49
Qiu, Z., Yao, T., Mei, T.: Learning spatio-temporal representation with pseudo-3D residual networks. In: 2017 IEEE International Conference on Computer Vision (ICCV). IEEE (2017)
Wang, Z.H., Liu, Z., Song, Y.Q., et al.: Densely connected deep U-Net for abdominal multi-organ segmentation. In: 2019 IEEE International Conference on Image Processing (ICIP). IEEE (2019)
Zhao, N., Tong, N., Ruan, D., Sheng, K.: Fully automated pancreas segmentation with two-stage 3D convolutional neural networks. In: Shen, D., Liu, T., Peters, T.M., Staib, L.H., Essert, C., Zhou, S., Yap, P.-T., Khan, A. (eds.) MICCAI 2019. LNCS, vol. 11765, pp. 201–209. Springer, Cham (2019). https://doi.org/10.1007/978-3-030-32245-8_23
Szegedy, C., Vanhoucke, V., Ioffe, S., Shlens, J., Wojna, Z.: Rethinking the inception architecture for computer vision. In: Proceedings of the IEEE Conference on Computer Vision and Pattern Recognition, pp. 2818–2826.AWERTQ (2016)
Wu, Y., He, K.: Group normalization. Int. J. Comput. Vis. (2018)
Lee, C., Xie, S., Gallagher, P.W., et al.: Deeply-supervised nets. Int. Conf. Artif. Intell. Stat. 562–570 (2015)
Duta, I.C., Liu, L., Zhu, F., et al.: Pyramidal convolution: rethinking convolutional neural networks for visual recognition. arXiv preprint arXiv:2006.11538 (2020)
Yu, Q., Xie, L., Wang, Y., et al.: Recurrent Saliency Transformation Network: Incorporating Multi-Stage Visual Cues for Small Organ Segmentation. In: 2018 IEEE/CVF Conference on Computer Vision and Pattern Recognition. IEEE (2018)
Zhou, X., Ito, T., Takayama, R., Wang, S., Hara, T., Fujita, H.: Three-dimensional CT image segmentation by combining 2D fully convolutional network with 3D majority voting. In: Carneiro, G., Mateus, D., Peter, L., Bradley, A., Tavares, J.M.R.S., Belagiannis, V., Papa, J.P., Nascimento, J.C., Loog, M., Lu, Z., Cardoso, J.S., Cornebise, J. (eds.) LABELS/DLMIA -2016. LNCS, vol. 10008, pp. 111–120. Springer, Cham (2016). https://doi.org/10.1007/978-3-319-46976-8_12
Roth, H.R., et al.: Deep learning and its application to medical image segmentation. Med. Imaging Technol. 36(2), 63–71 (2018)
Long, J., Evan, S., Trevor, D.: Fully convolutional networks for semantic segmentation. In: Proceedings of the IEEE Conference on Computer Vision and Pattern Recognition (2015)
Yushkevich, P.A., Piven, J., Hazlett, H.C., et al.: User-guided 3D active contour segmentation of anatomical structures: significantly improved efficiency and reliability. Neuroimage 31(3), 1116–1128 (2006)
Cheng, J., Liu, Y., Tang, X., Sheng, V.S., Li, M., et al.: DDOS attack detection via multi-scale convolutional neural network. Comput. Mater. Continua 62(3), 1317–1333 (2020)
Acknowledgment
This work was supported by Zhenjiang Key Deprogram “Fire Early Warning Technology Based on Multimodal Data Analysis” (SH2020011) Jiangsu Emergency Management Science and Technology Project “Research on Very Early Warning of Fire Based on Multi-modal Data Analysis and Multi-Intelligent Body Technology” (YJGL-TG-2020–8).
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2021 Springer Nature Switzerland AG
About this paper
Cite this paper
Wang, W. et al. (2021). Efficient 3D Pancreas Segmentation Using Two-Stage 3D Convolutional Neural Networks. In: Sun, X., Zhang, X., Xia, Z., Bertino, E. (eds) Artificial Intelligence and Security. ICAIS 2021. Lecture Notes in Computer Science(), vol 12736. Springer, Cham. https://doi.org/10.1007/978-3-030-78609-0_17
Download citation
DOI: https://doi.org/10.1007/978-3-030-78609-0_17
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-030-78608-3
Online ISBN: 978-3-030-78609-0
eBook Packages: Computer ScienceComputer Science (R0)