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Prophylactic Resections of the Pancreas Pathologies

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Prophylactic Surgery

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Abstract

Pancreatic surgery has been one of the addresses of the most challenging interventions in surgery due to its organ location, neighborhood, and high perioperative morbidity. Pancreatic cancers are generally asymptomatic and among the deadliest cancers. Early diagnosis and management are the most critical factors in the success of the treatment. With the detection of precancerous features of cystic lesions with advanced screening methods, pancreatectomies with various extents and interventional procedures have started to be performed for prophylactic and therapeutic purposes of cystic lesions. In cases where the diagnosis is difficult and risk increases by the remaining lesion, prophylactic resection appears as an option. While nearly 20 different types of cystic lesions are detected in the pancreas, serous cysts, mucinous cysts, intraductal papillary mucinous neoplasias, and solid pseudopapillary tumors constitute 95% of the cases. The majority of pancreatic tumors are sporadic (90%), and 3–10% of the cases are the tumors with a germline (hereditary) transition. The approach to the treatment of sporadic pancreatic tumors is primarily surgical treatment. In hereditary pancreatic tumors, the approach is for prophylactic purposes. In this section, the place of prophylactic surgery in hereditary pancreatic tumors, cystic neoplasms, precursor lesions with benign character, and some miscellaneous conditions are going to be evaluated.

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  1. Department of Surgery, Section of Hepatopancreatobiliary Surgery, Izmir Kâtip Çelebi University School of Medicine, İzmir, Turkey

    Osman Nuri Dilek

  2. Department of General Surgery, İzmir Katip Çelebi University Atatürk Training and Research Hospital, İzmir, Turkey

    Turan Acar

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  1. Department of Surgery, Section of Hepatopancreatobiliary Surgery, Izmir Kâtip Çelebi University School of Medicine, İzmir, Turkey

    Osman Nuri Dilek

  2. Department of Surgery, Section for Surgical Research, Medical University of Graz, Graz, Steiermark, Austria

    Selman Uranues

  3. Department of Surgery, Westchester Medical Center and New York Medical College, Valhalla, NY, USA

    Rifat Latifi

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Dilek, O.N., Acar, T. (2021). Prophylactic Resections of the Pancreas Pathologies. In: Dilek, O.N., Uranues, S., Latifi, R. (eds) Prophylactic Surgery. Springer, Cham. https://doi.org/10.1007/978-3-030-66853-2_10

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