Skip to main content

Basic Lung Ultrasonography for the Nephrologist

  • Chapter
  • First Online:
Imaging in Nephrology

Abstract

Hyperhydration is characterized by increased quantity and altered distribution of body fluids. Fluid overload is frequently found in critically ill patients with acute kidney injury (AKI) and in heart failure patients and is associated with adverse outcomes. Although physical examination is still the first choice for the assessment of the hydration state, it is imprecise and often unreliable. Nowadays novel techniques are employed, sometimes together, in a comprehensive assessment strategy previously proposed as the “5B” approach: body weight changes, blood volume online monitoring, bioimpedance spectroscopy (BIS), B-natriuretic peptide, and body ultrasound (US), which includes inferior vena cava (IVC) diameter measure and lung US (LUS). The modern LUS has extended its field of clinical application from cardiology and intensive care setting to hemodialysis patients since the clinical evaluation alone has proven to be rather imprecise in estimating the correct “dry weight.” B-line detection by LUS has recently been confirmed to be superior in sensitivity to clinical signs of fluid overload such as lung crackles and peripheral edema. Furthermore, LUS has shown a greater predictive power for hydration-related cardiovascular morbidity and mortality than NYHA score or echocardiography. Based on evidence, LUS can be considered a valid diagnostic and prognostic tool for pulmonary congestion measurement in both extracorporeal and peritoneal dialysis patients.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 129.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Hardcover Book
USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Volpicelli G. Lung sonography. J Ultrasound Med. 2013;32:165–71.

    Article  Google Scholar 

  2. Agarwal R. Hypervolemia is associated with increased mortality among hemodialysis patients. Hypertension. 2010;56(3):512–7.

    Article  CAS  Google Scholar 

  3. Onofriescu MS, Voroneanu L, Hogas S, et al. Overhydration, cardiac function and survival in hemodialysis patients. PLoS One. 2015;10(8):e0135691.

    Article  Google Scholar 

  4. Covic A, Siriopol D, Voroneanu L. Use of lung ultrasound for the assessment of volume status in CKD. Am J Kidney Dis. 2018;71(3):412–22.

    Article  Google Scholar 

  5. Noble VE, Murray AF, Capp R, Sylvia-Reardon MH, Steele DJR, Liteplo A. Ultrasound assessment for extravascular lung water in patients undergoing hemodialysis. Time course for resolution. Chest. 2009;135(6):1433–9.

    Article  Google Scholar 

  6. Mallamaci F, Benedetto FA, Tripepi R, Rastelli S, Castellino P, Tripepi G, et al. Detection of pulmonary congestion by chest ultrasound in dialysis patients. JACC Cardiovasc Imaging. 2010;3(6):586–94.

    Article  Google Scholar 

  7. Trezzi M, Torzillo D, Ceriani E, Costantino G, Caruso S, Damavandi PT, et al. Lung ultrasonography for the assessment of rapid extravascular water variation: evidence from hemodialysis patients. Intern Emerg Med. 2013;8(5):409–15.

    Article  Google Scholar 

  8. Vitturi N, Dugo M, Soattin M, Simoni F, Maresca L, Zagatti R, et al. Lung ultrasound during hemodialysis: the role in the assessment of volume status. Int Urol Nephrol. 2014;46(1):169.

    Article  CAS  Google Scholar 

  9. Donadio C, Bozzoli L, Colombini E, Pisanu G, Ricchiuti G, Picano E, et al. Effective and timely evaluation of pulmonary congestion: qualitative comparison between lung ultrasound and thoracic bioelectrical impedance in maintenance hemodialysis patients. Medicine (Baltimore). 2015;94(6):e473.

    Article  CAS  Google Scholar 

  10. Enia G, Torino C, Panuccio V, Tripepi R, Postorino M, Aliotta R, et al. Asymptomatic pulmonary congestion and physical functioning in hemodialysis patients. Clin J Am Soc Nephrol. 2013;8(8):1343–8.

    Article  Google Scholar 

  11. Panuccio V, Enia G, Tripepi R, Torino C, Garozzo M, Battaglia GG, et al. Chest ultrasound and hidden lung congestion in peritoneal dialysis patients. Nephrol Dial Transplant. 2012;27(9):3601–5.

    Article  Google Scholar 

  12. Enia G, Tripepi R, Panuccio V, Torino C, Garozzo M, Battaglia GG, et al. Pulmonary congestion and physical functioning in peritoneal dialysis patients. Perit Dial Int. 2012;32(5):531–6.

    Article  CAS  Google Scholar 

  13. Paudel K, Kausik T, Visser A, Ramballi C, Fan SL. Comparing lung ultrasound with bioimpedance spectroscopy for evaluating hydration in peritoneal dialysis patients. Nephrology. 2015;20(1):1–5.

    Article  CAS  Google Scholar 

  14. Torino C, Gargani L, Sicari R, Letachowicz K, Ekart R, Fliser D, et al. The agreement between auscultation and lung ultrasound in hemodialysis patients: the LUST study. Clin J Am Soc Nephrol. 2016;11(10):2005–11.

    Article  Google Scholar 

  15. Allinovi M, Saleem M, Romagnani P, Nazerian P, Hayes W. Lung ultrasound: a novel technique for detecting fluid overload in children on dialysis. Nephrol Dial Transpl. 2016:1–6.

    Google Scholar 

  16. Marino F, Martorano C, Tripepi R, Bellantoni M, Tripepi G, Mallamaci F, Zoccali C. Subclinical pulmonary congestion is prevalent in nephrotic syndrome. Kidney Int. 2016;89(2):421–8.

    Article  Google Scholar 

  17. Zoccali C, Torino C, Tripepi R, Tripepi G, D’Arrigo G, Postorino M, et al. Pulmonary congestion predicts cardiac events and mortality in ESRD. J Am Soc Nephrol. 2013;24(4):639–46.

    Article  Google Scholar 

  18. Saad MM, Kamal J, Moussaly E, Karam B, Mansour W, Gobran E, Abbasi SH, Mahgoub A, Singh P, Hardy R, Das D, Brown C, Kapoor M, Demissie S, Kleiner MJ, El Charabaty E, El Sayegh SE. Relevance of B-lines on lung ultrasound in volume overload and pulmonary congestion: clinical correlations and outcomes in patients on hemodialysis. Cardiorenal Med. 2018;8(2):83–91.

    Article  Google Scholar 

  19. Siriopol D, Hogas S, Voroneanu L, Onofriescu M, Apetrii M, Oleniuc M, et al. Predicting mortality in haemodialysis patients: a comparison between lung ultrasonography, bioimpedance data and echocardiography parameters. Nephrol Dial Transplant. 2013;28(July):2851–9.

    Article  Google Scholar 

  20. Siriopol D, Voroneanu L, Hogas S, Apetrii M, Gramaticu A, Dumea R, et al. Bioimpedance analysis versus lung ultrasonography for optimal risk prediction in hemodialysis patients. Int J Cardiovasc Imaging. 2016;32(2):263–70.

    Article  Google Scholar 

  21. Basso F, Milan Manani S, Cruz DN, Teixeira C, Brendolan A, Nalesso F, et al. Comparison and reproducibility of techniques for fluid status assessment in chronic hemodialysis patients. Cardiorenal Med. 2013;3(2):104–12.

    Article  CAS  Google Scholar 

  22. Bedetti G, Gargani L, Corbisiero A, Frassi F, Poggianti E, Mottola G. Evaluation of ultrasound lung comets by hand-held echocardiography. Cardiovasc Ultrasound. 2006;4:34.

    Article  CAS  Google Scholar 

  23. Noble VE, Lamhaut L, Capp R, Bosson N, Liteplo A, Marx J-S, et al. Evaluation of a thoracic ultrasound training module for the detection of pneumothorax and pulmonary edema by prehospital physician care providers. BMC Med Educ. 2009 Jan;9:3.

    Article  Google Scholar 

  24. Gargani L, Sicari R, Raciti M, Serasini L, Passera M, Torino C, et al. Efficacy of a remote web-based lung ultrasound training for nephrologists and cardiologists: a LUST trial sub-project. Nephrol Dial Transplant. 2016:gfw329.

    Google Scholar 

  25. Jambrik Z, Monti S, Coppola V, Agricola E, Mottola G, Miniati M, et al. Usefulness of ultrasound lung comets as a nonradiologic sign of extravascular lung water. Am J Cardiol. 2004;93(10):1265–70.

    Article  Google Scholar 

  26. Gargani L. Lung ultrasound: a new tool for the cardiologist. Cardiovasc Ultrasound. 2011;9:6.

    Article  Google Scholar 

  27. Volpicelli G, Elbarbary M, Blaivas M, Lichtenstein DA, Mathis G, Kirkpatrick AW, et al. International evidence-based recommendations for point-of-care lung ultrasound. Intensive Care Med. 2012;38(4):577–91.

    Article  Google Scholar 

  28. Gargani L, Volpicelli G. How I do it: lung ultrasound. Cardiovasc Ultrasound. 2014;12(1):1–10.

    Article  Google Scholar 

  29. Narula J, Chandrashekhar Y, Braunwald E. Time to add a fifth pillar to bedside physical examination: inspection, palpation, percussion, auscultation, and insonation. JAMA Cardiol. 2018;3(4):346–50.

    Article  Google Scholar 

  30. Di Nicolò P, Magnoni G, Granata A. In-depth review lung ultrasound in hemodialysis: a card to be played? Blood Purif. 2017;44:1–7.

    Article  Google Scholar 

  31. Zoccali C. Lung ultrasound in the management of fluid volume in dialysis patients: potential usefulness. Semin Dial. 2017;30(1):6–9.

    Article  Google Scholar 

  32. Sherman RA. Crackles and comets: lung ultrasound to detect pulmonary congestion in patients on dialysis is coming of age. Clin J Am Soc Nephrol. 2016:1–3.

    Google Scholar 

  33. Sicari R, Galderisi M, Voigt J-U, Habib G, Zamorano JL, Lancellotti P, et al. The use of pocket-size imaging devices: a position statement of the European Association of Echocardiography. Eur J Echocardiogr. 2011 Feb;12(2):85–7.

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2021 Springer Nature Switzerland AG

About this chapter

Check for updates. Verify currency and authenticity via CrossMark

Cite this chapter

Gargani, L., Volpicelli, G., Cardinale, L. (2021). Basic Lung Ultrasonography for the Nephrologist. In: Granata, A., Bertolotto, M. (eds) Imaging in Nephrology. Springer, Cham. https://doi.org/10.1007/978-3-030-60794-4_27

Download citation

  • DOI: https://doi.org/10.1007/978-3-030-60794-4_27

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-60792-0

  • Online ISBN: 978-3-030-60794-4

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics