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Kidney Tumor

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Practical Genitourinary Pathology

Part of the book series: Practical Anatomic Pathology ((PAP))

Abstract

The spectrum of renal neoplasms continues to expand with better understanding of histology, immunohistochemistry, and genetics, such that many renal cancer variants are now recognized. Diagnostic challenges for the pathologist include classifying renal masses based on biopsy material, as well as distinguishing subtle variants that may have implications for prognosis or diagnosis of hereditary cancer syndromes. This chapter addresses challenges in classifying renal tumor types and distinguishing entities with morphologic overlap. The common questions addressed include grading, staging, and immunohistochemical and molecular tools to resolve diagnostic problems. Most common renal tumor types include clear cell, papillary, chromophobe, and clear cell papillary (tubulopapillary) renal cell carcinomas; however, rarer variants are also discussed including hereditary cancer syndromes, sarcomatoid tumors, metanephric, and nephroblastic tumors.

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  1. Department of Pathology, University of Washington, Seattle, WA, USA

    Maria Tretiakova

  2. Department of Pathology, Cleveland Clinic, Cleveland, OH, USA

    Sean R. Williamson

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    Ximing J. Yang

  2. Department of Pathology and Laboratory Medicine, Tufts Medical Center, Tufts School of Medicine, Boston, MA, USA

    Ming Zhou

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Tretiakova, M., Williamson, S.R. (2021). Kidney Tumor. In: Yang, X.J., Zhou, M. (eds) Practical Genitourinary Pathology. Practical Anatomic Pathology. Springer, Cham. https://doi.org/10.1007/978-3-030-57141-2_1

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