Abstract
Iron is needed in micro-quantities for cellular homeostasis. In humans, iron is bound to transferrin and ferritin, the essential proteins for cellular functions. The human body maintains an optimal iron content through an intrinsic mechanism. The accumulation of iron in soft tissues leads to clinical attention. In microorganisms such as bacteria and fungi, iron is required for their optimal growth. The microorganisms acquire iron from the hosts they infect by secreting siderophores. Siderophores are the iron-chelating agents with low molecular weight. While a large number of studies are available on the siderophores secreted by bacteria, a minimum information is known about the siderophores secreted by fungi. In this chapter, we summarized the basic information on fungal siderophores based on the information available in the published biomedical literature. We focused on the classification, iron uptake and storage, chemistry and biosynthesis, and application of fungal siderophores, with a special reference to potential research areas.
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Arputhanantham, S.S., Raja, K., Shanmugam, L., Raman, V. (2021). Basics of Fungal Siderophores: Classification, Iron Transport and Storage, Chemistry and Biosynthesis, Application, and More. In: Dhusia, K., Raja, K., Ramteke, P. (eds) Fungal Siderophores. Fungal Biology. Springer, Cham. https://doi.org/10.1007/978-3-030-53077-8_1
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