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Staging and Grouping of Retinoblastoma

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Albert and Jakobiec's Principles and Practice of Ophthalmology

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Abstract

The classification of most tumors results from an interaction between pathologists, oncologists, and the surgeon often aided by a tissue biopsy. Retinoblastoma is unique among childhood malignancies in that a direct biopsy is not done for diagnosis and currently classification is based on clinical features only. Additionally, for solid childhood malignancies, survival of the patient is generally the sole endpoint to measure therapeutic efficacy. However, in retinoblastoma, effective salvage of the globe is another critical and clinically relevant endpoint. For this reason group classifications for retinoblastoma are often tumor classifications; to be successful, they must reflect clinical reality and must be updated as the treatments change.

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Author information

Authors and Affiliations

  1. The Vision Center, Children’s Hospital Los Angeles, Los Angeles, CA, USA

    Jesse L. Berry

  2. USC Roski Eye Institute, Keck School of Medicine of USC, University of Southern California (USC), Los Angeles, CA, USA

    Jesse L. Berry

Authors
  1. Jesse L. Berry
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Editor information

Editors and Affiliations

  1. Casey Eye Institute, Oregon Health & Science, Portland, OR, USA

    Daniel M. Albert

  2. Department of Ophthalmology, Massachusetts Eye and Ear, Massachusetts General Hospital, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, USA

    Joan W. Miller

  3. Department of Ophthalmology, University of Illinois College of Medicine, University of Illinois at Chicago, Chicago, IL, USA

    Dimitri T. Azar

  4. Department of Ophthalmology, Massachusetts Eye and Ear, Harvard Medical School, Boston, MA, USA

    Lucy H. Young

Section Editor information

  1. Department of Ophthalmology, Scheie Eye Institute, University of Pennsylania, Philadelphia, USA

    Joan Marie O’Brien

  2. Department of Ophthalmology, Retina Service, Harvard Medical School; Massachusetts Eye and Ear Infirmary, Boston, MA, USA

    Evangelos S. Gragoudas

  3. The MD Anderson Cancer Center, Texas, USA

    Dan S. Gombos

  4. Retina Service, Massachusetts Eye and Ear, Harvard Medical School, Boston, USA

    Mary E. Aronow

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Berry, J.L. (2022). Staging and Grouping of Retinoblastoma. In: Albert, D.M., Miller, J.W., Azar, D.T., Young, L.H. (eds) Albert and Jakobiec's Principles and Practice of Ophthalmology. Springer, Cham. https://doi.org/10.1007/978-3-030-42634-7_267

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  • DOI: https://doi.org/10.1007/978-3-030-42634-7_267

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-42633-0

  • Online ISBN: 978-3-030-42634-7

  • eBook Packages: MedicineReference Module Medicine

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