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Retinoblastoma: Staging and Grouping

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Clinical Ophthalmic Oncology

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Abstract

A commonly used tumor classification is essential in order to plan initial treatment, determine prognosis, assess treatment response, compare outcomes, and plan clinical trials. Berman maintains that for tumor classifications to be successful, they must reflect clinical reality and must be changed as information is accrued. Almost never does the staging of the tumor rest solely with the subspecialty surgeon. It usually results from interaction between pathologists, oncologists, and the surgeon often aided by a tissue biopsy. This is not the case for retinoblastoma, and currently classification is based on clinical features. For almost all solid childhood malignancies, survival of the patient is the sole end point against which to assess treatment efficacy and side effects. In retinoblastoma, effective salvage of the globe is a secondary end point.

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Author information

Authors and Affiliations

  1. Department of Ophthalmology, USC Roski Eye Institute, Keck School of Medicine of USC, Children’s Hospital Los Angeles, Los Angeles, CA, USA

    Jesse L. Berry

  2. Department of Ophthalmology, Children’s Hospital Los Angeles, University of Southern California, Los Angeles, CA, USA

    A. Linn Murphree

  3. USC Roski Eye Institute, Department of Ophthalmology, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA

    A. Linn Murphree

Authors
  1. Jesse L. Berry
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  2. A. Linn Murphree
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Corresponding author

Correspondence to Jesse L. Berry .

Editor information

Editors and Affiliations

  1. Associate Professor of Ophthalmology, Children’s Hospital Los Angeles, The USC Roski Eye Institute Keck School of Medicine, Los Angeles, CA, USA

    Jesse L. Berry

  2. Children’s Hospital Los Angeles, The USC Roski Eye Institute, Keck School of Medicine, Los Angeles, CA, USA

    Jonathan W. Kim

  3. University of Oxford, Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, Oxford, UK

    Bertil E. Damato

  4. Department of Ophthalmic Oncology, Cole Eye Institute, Cleveland Clinic, Cleveland, OH, USA

    Arun D. Singh

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Berry, J.L., Murphree, A.L. (2019). Retinoblastoma: Staging and Grouping. In: Berry, J., Kim, J., Damato, B., Singh, A. (eds) Clinical Ophthalmic Oncology. Springer, Cham. https://doi.org/10.1007/978-3-030-11123-6_3

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  • DOI: https://doi.org/10.1007/978-3-030-11123-6_3

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-11122-9

  • Online ISBN: 978-3-030-11123-6

  • eBook Packages: MedicineMedicine (R0)

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