Abstract
Bioactive molecules are secondary metabolites having pharmacological activities. They may be harmful or useful depending upon the nature and dose of respective bioactive molecule. It includes carbohydrate, protein, fats, nucleic acids, enzymes which maintains homeostasis of the body. Fats are the biomolecule which are highly rich in caloric value (9.3 kcal/mole). Fat molecules are present in the body as food reservoirs, structural components, heat insulator, source of hormones and bile acids and act as carrier for vitamins. Oils also help in the absorption and assimilation of nutrients, improves memory power and lubricates connective tissue and organs. Fat and oil consumption can help alleviate various ailments such as dry skin, stiffness, constipation and arthritis.
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References
Abdelwahab SI, Abdul AB, Zain ZN, Hadi AH (2012) Zerumbone inhibits interleukin-6 and induces apoptosis and cell cycle arrest in ovarian and cervical cancer cells. Int Immunopharmacol 12(4):594–602
Albert-Puleo M (1978) Mythobotany, pharmacology, and chemistry of thujone-containing plants and derivatives. Econ Bot 32(1):65–74
Baby S, Dan M, Thaha AR, Johnson AJ, Kurup R, Balakrishnapillai P, Lim CK (2009) High content of zerumbone in volatile oils of Zingiber zerumbet from southern India and Malaysia. Flavour Fragr J 24(6):301–308
Baer E, Pavanaram SK (1961) N-Methylcephalins I. synthesis of distearoyl l-α-glycerylphosphoryl-(n-methyl) ethanolamine. J Biol Chem 236(5):1269–1272
Barceloux DG (2008) Medical toxicology of natural substances: foods, fungi, medicinal herbs, plants, and venomous animals. Wiley, Hoboken
Burke YD, Stark MJ, Roach SL, Sen SE, Crowell PL (1997) Inhibition of pancreatic cancer growth by the dietary isoprenoids farnesol and geraniol. Lipids 32(2):151–156
Clark GS (1998) Geraniol. Perfum Flavor 23(3):19–25
Compher C, Seto RW, Lew JI, Rombeau JL (1997) Dietary fiber and its clinical applications to enteral nutrition. In: Clinical nutrition: enteral and tube feeding. Saunders, Philadelphia, pp 81–95
Crowell PL, Elson CE (2001) Isoprenoids, health and disease. In: Wildman REC (ed) Nutraceuticals and functional foods. CRC Press, Boca Raton, pp 31–54
de Almeida PM, Magalhães RM, Torres DM, Cavalcante RC, Mota FS, Coelho EM, Moreira HP, Lima GC, da Costa Araújo PC, Cardoso JH, de Souza AN (2015) Gastroprotective effect of alpha-pinene and its correlation with antiulcerogenic activity of essential oils obtained from Hyptis species. Pharmacogn Mag 11(41):123
Dietschy JM, Turley SD (2001) Cholesterol metabolism in the brain. Curr Opin Lipidol 12(2):105–112
Fless GM, Rolih CA, Scanu AM (1984) Heterogeneity of human plasma lipoprotein (a). Isolation and characterization of the lipoprotein subspecies and their apoproteins. J Biol Chem 259(18):11470–11478
Gillard BK, Thurmon LT, Marcus DM (1993) Variable subcellular localization of glycosphingolipids. Glycobiology 3(1):57–67
Havel RJ, Eder HA, Bragdon JH (1955) The distribution and chemical composition of ultracentrifugally separated lipoproteins in human serum. J Clin Invest 34(9):1345–1353
Hierro I, Valero A, Navarro MC (2006) In vivo larvicidal activity of monoterpenic derivatives from aromatic plants against L3 larvae of Anisakis simplex sl. Phytomedicine 13(7):527–531
Horton HR, Moran LA, Ochs RS, Rawn JD, Scrimgeour KG (1996) Principles of biochemistry. Prentice Hall, Upper Saddle River
Huang X, Xiao Y, Köllner TG, Zhang W, Wu J, Wu J, Guo Y, Zhang Y (2013) Identification and characterization of (E)-β-caryophyllene synthase and α/β-pinene synthase potentially involved in constitutive and herbivore-induced terpene formation in cotton. Plant Physiol Biochem 73:302–308
Jiang Z, Jacob JA, Loganathachetti DS, Nainangu P, Chen B (2017) β-Elemene: mechanistic studies on cancer cell interaction and its chemosensitization effect. Front Pharmacol 8:105
Kamatou GP, Vermaak I, Viljoen AM (2012) Eugenol—from the remote Maluku Islands to the international market place: a review of a remarkable and versatile molecule. Molecules 17(6):6953–6981
Kolassa N (2013) Menthol differs from other terpenic essential oil constituents. Regul Toxicol Pharmacol 65(1):115–118
Kontush A, Chapman MJ (2010) Antiatherogenic function of HDL particle subpopulations: focus on antioxidative activities. Curr Opin Lipidol 21(4):312–318
Koudinov AR, Koudinova NV (2005) Cholesterol homeostasis failure as a unifying cause of synaptic degeneration. J Neurol Sci 229:233–240
Kuske TT, Feldman EB (1987) Hyperlipoproteinemia, atherosclerosis risk, and dietary management. Arch Intern Med 147(2):357–360
Laszlo P (2008) Citrus: a history. University of Chicago Press, Chicago
Lawrence BM (2006) Mint: the genus Mentha. CRC Press, Boca Raton
Li D, Weng S, Yang B, Zander DS, Saldeen T, Nichols WW, Khan S, Mehta JL (1999) Inhibition of arterial thrombus formation by ApoA1 Milano. Arterioscler Thromb Vasc Biol 19(2):378–383
Lopez LM, Grimes DA, Schulz KF, Curtis KM, Chen M (2014) Steroidal contraceptives: effect on bone fractures in women. Cochrane Database Syst Rev 6
Malhotra R (2012) Membrane glycolipids: functional heterogeneity: a review. Biochem Anal Biochem 1(108):10–4172
Mashaghi S, Jadidi T, Koenderink G, Mashaghi A (2013) Lipid nanotechnology. Int J Mol Sci 14(2):4242–4282
Misra BB, Dey S (2013) Evaluation of in vivo anti-hyperglycemic and antioxidant potentials of α-santalol and sandalwood oil. Phytomedicine 20(5):409–416
Mišurcová L, Ambrožová J, Samek D (2011) Seaweed lipids as nutraceuticals. In: Advances in food and nutrition research, vol 64. Academic Press, Amsterdam, pp 339–355
Morice AH, Marshall AE, Higgins KS, Grattan TJ (1994) Effect of inhaled menthol on citric acid induced cough in normal subjects. Thorax 49(10):1024–1026
Olsen RW (2000) Absinthe and γ-aminobutyric acid receptors. Proc Natl Acad Sci U S A 97(9):4417–4418
Ong KL, Morris MJ, McClelland RL, Hughes TM, Maniam J, Fitzpatrick AL, Martin SS, Luchsinger JA, Rapp SR, Hayden KM, Sandfort V (2017) Relationship of lipids and lipid-lowering medications with cognitive function: the multi-ethnic study of atherosclerosis. Am J Epidemiol 187(4):767–776
Papachristos DP, Karamanoli KI, Stamopoulos DC, Menkissoglu-Spiroudi U (2004) The relationship between the chemical composition of three essential oils and their insecticidal activity against Acanthoscelides obtectus (Say). Pest Manag Sci 60(5):514–520
Pattenden G, Gonzalez MA, McCulloch S, Walter A, Woodhead SJ (2004) A total synthesis of estrone based on a novel cascade of radical cyclizations. Proc Natl Acad Sci U S A 101(33):12024–12029
Riccardi G, Giacco R, Rivellese AA (2004) Dietary fat, insulin sensitivity and the metabolic syndrome. Clin Nutr 23(4):447–456
Sarpietro MG, Di Sotto A, Accolla ML, Castelli F (2015) Interaction of β-caryophyllene and β-caryophyllene oxide with phospholipid bilayers: differential scanning calorimetry study. Thermochim Acta 600:28–34
Scolnik MD, Servadio C, Abramovici A (1994) Comparative study of experimentally induced benign and atypical hyperplasia in the ventral prostate of different sat strains. J Androl 15(4):287–297
Shapiro MD, Fazio S (2017) Apolipoprotein B-containing lipoproteins and atherosclerotic cardiovascular disease. F1000 Res 6:134
Simmons G, Pruitt W, Pruitt K (2015) Diverse roles of SIRT1 in cancer biology and lipid metabolism. Int J Mol Sci 16(1):950–965
Singh G, Marimuthu P, de Heluani CS, Catalan CA (2006) Antioxidant and biocidal activities of Carum nigrum (seed) essential oil, oleoresin, and their selected components. J Agric Food Chem 54(1):174–181
Spoeckner S, Wray V, Nimtz M, Lang S (1999) Glycolipids of the smut fungus Ustilago maydis from cultivation on renewable resources. Appl Microbiol Biotechnol 51(1):33–39
Stamler J, Daviglus ML, Garside DB, Dyer AR, Greenland P, Neaton JD (2000) Relationship of baseline serum cholesterol levels in 3 large cohorts of younger men to long-term coronary, cardiovascular, and all-cause mortality and to longevity. JAMA 284(3):311–318
Stancu C, Sima A (2001) Statins: mechanism of action and effects. J Cell Mol Med 5(4):378–387
Tighe S, Gao YY, Tseng SC (2013) Terpinen-4-ol is the most active ingredient of tea tree oil to kill Demodex mites. Transl Vis Sci Technol 2(7):2
Uauy R, Dangour AD (2006) Nutrition in brain development and aging: role of essential fatty acids. Nutr Rev 64(Suppl_2):S24–S33
Vallianou I, Peroulis N, Pantazis P, Hadzopoulou-Cladaras M (2011) Camphene, a plant-derived monoterpene, reduces plasma cholesterol and triglycerides in hyperlipidemic rats independently of HMG-CoA reductase activity. PLoS One 6(11):e20516
Zak A, Vecka M, Tvrzicka E, Jachymova M, Dusejovska M, Janikova L, Stankova B, Vavrova L, Kodydkova J, Zeman M (2007) Composition of the nonesterified fatty acids and lipid peroxidation in metabolic syndrome. Cas Lek Cesk 146(5):484–491
Zhang Y, Mu XD, Li EZ, Luo Y, Song N, Qu XJ, Hu XJ, Liu YP (2013) The role of E3 ubiquitin ligase Cbl proteins in β-elemene reversing multi-drug resistance of human gastric adenocarcinoma cells. Int J Mol Sci 14(5):10075–10089
Acknowledgement
AKS acknowledge financial support from CSIR, India in the form of Junior Research fellowship. PPK acknowledges financial support from Council of Scientific and Industrial Research (CSIR)-University Grants Commission (UGC), India, in the form of Senior Research fellowship. SK acknowledges DST, India and UGC, India for providing financial support in the form of DST-SERB Grant [EEQ/2016/000350] and UGC-BSR Research Start- Up-Grant [No. F.30–372/2017 (BSR)] respectively. SK also acknowledges DST-FIST India for the financial support provided to Department of Biochemistry, Central University of Punjab, India.
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Kumar, A. et al. (2020). Fats and Oils as Sources of Bioactive Molecules. In: Egbuna, C., Dable Tupas, G. (eds) Functional Foods and Nutraceuticals. Springer, Cham. https://doi.org/10.1007/978-3-030-42319-3_6
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DOI: https://doi.org/10.1007/978-3-030-42319-3_6
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