Abstract
Nanoparticles (NPs) are tiny materials exhibiting a size range of 1–100 nm. Nanoparticles are used in biomedical applications like bioimaging, therapy, drug delivery, and biosensors; therapeutic applications such as treatment of cancer, inflammatory diseases, like inflammatory bowel diseases, inflammatory lung diseases, ophthalmic inflammatory diseases, and rheumatoid arthritis, wound healing, and cardiovascular diseases; nanoremediation; food industry; and agriculture. Metal oxides NPs and gold nanoparticles (AuNPs) are used in magnetic resonance imaging (MRI), positron-emitting tomography (PET), and computed tomography (CT). Nano-conjugates of drugs possess more cytotoxicity as compared to without NPs drug treatment of myeloid leukemia. Nanoparticles like gold half shell multifunctional NPs, polylactic-co-glycolic acid (PLGA) NPs, and solid lipid nanoparticles have been used for the delivery of drugs at the inflammatory site for the treatment of inflammatory diseases. AuNPs can be used as antioxidant, antimicrobial, and anti-inflammation agents for wound healing and burns. Nanoscale metals, carbon nanotubes, zeolites, fibers, metal oxides, and titanium oxides have been explored for remediation of toxic compounds. Nanoscale food additives can be used to increase the shelf life, flavor, texture, nutrient composition or even to detect the contaminants or pathogens in food. Biodegradable plastics such as polybutylene succinate (PBS), polylactic acid (PLA), and polyhydroxybutyrate (PHB) are polymers that can be easily degraded to nontoxic compounds in the presence of microorganisms. Nano-TiO2 enhances the absorption of inorganic nutrients, accelerates the breakdown of organic substance, and can quench oxygen free radicals produced during the photosynthetic, so it can increase the rate of photosynthesis. Nanosensors like parathion, methyl parathion, pirimicarb, fenitrothion, and paraoxon are used to detect the residues of pesticides. Nanoparticles can also be used as biomarkers for the detection of viral, bacterial, and fungal pathogens in agriculture.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Similar content being viewed by others
References
Alam S, Anand C, Ariga K, Mori T, Vinu A (2009) Unusual magnetic properties of size-controlled iron oxide nanoparticles grown in a nanoporous matrix with tunable pores. Angew Chem Int Ed 48(40):7358–7361
Anand P, Thomas SG, Kunnumakkara AB, Sundaram C, Harikumar KB, Sung B, Tharakan ST, Misra K, Priyadarsini IK, Rajasekharan KN (2008) Biological activities of curcumin and its analogues (congeners) made by man and mother nature. Biochem Pharmacol 76(11):1590–1611
Araújo J, Vega E, Lopes C, Egea M, Garcia M, Souto E (2009) Effect of polymer viscosity on physicochemical properties and ocular tolerance of FB-loaded PLGA nanospheres. Colloids Surf B: Biointerfaces 72(1):48–56
Arvizo RR, Bhattacharyya S, Kudgus RA, Giri K, Bhattacharya R, Mukherjee P (2012) Intrinsic therapeutic applications of noble metal nanoparticles: past, present and future. Chem Soc Rev 41(7):2943–2970
Baneyx G, Baugh L, Vogel V (2001) Coexisting conformations of fibronectin in cell culture imaged using fluorescence resonance energy transfer. Proc Natl Acad Sci USA 98(25):14464–14468
Baran E, Hasirci V (2002) In vivo half life of nanoencapsulated L-asparaginase. J Mater Sci Mater Med 13(12):1113–1121
Barrera P, Blom A, Van Lent PL, Van Bloois L, Beijnen JH, Van Rooijen N, De Waal Malefijt MC, Van De Putte L, Storm G, Van Den Berg WB (2000) Synovial macrophage depletion with clodronate-containing liposomes in rheumatoid arthritis. Arthritis Rheum 43(9):1951–1959
Bergeson LL (2010) Nanosilver: US EPA’s pesticide office considers how best to proceed. Environ Qual Manag 19(3):79–85
Bhattacharyya A, Duraisamy P, Govindarajan M, Buhroo AA, Prasad R (2016) Nano-biofungicides: emerging trend in insect pest control. In: Prasad R (ed) Advances and applications through fungal Nanobiotechnology. Springer International Publishing Switzerland, pp 307–319
Bhattacharya R, Mukherjee P, Xiong Z, Atala A, Soker S, Mukhopadhyay D (2004) Gold nanoparticles inhibit VEGF165-induced proliferation of HUVEC cells. Nano Lett 4(12):2479–2481
Bokara KK, Kim JY, Lee YI, Yun K, Webster TJ, Lee JE (2013) Biocompatibility of carbon nanotubes with stem cells to treat CNS injuries. Anat Cell Biol 46(2):85–92
Boonham N, Glover R, Tomlinson J, Mumford R (2008) Exploiting generic platform technologies for the detection and identification of plant pathogens. In: Sustainable disease management in a European context. Springer, New York, NY, pp 355–363
Bordes P, Pollet E, Avérous L (2009) Nano-biocomposites: biodegradable polyester/nanoclay systems. Prog Polym Sci 34(2):125–155
Bouwmeester H, Dekkers S, Noordam MY, Hagens WI, Bulder AS, De Heer C, Ten Voorde SE, Wijnhoven SW, Marvin HJ, Sips AJ (2009) Review of health safety aspects of nanotechnologies in food production. Regul Toxicol Pharmacol 53(1):52–62
Boyd JH, Kan B, Roberts H, Wang Y, Walley KR (2008) S100A8 and S100A9 mediate endotoxin-induced cardiomyocyte dysfunction via the receptor for advanced glycation end products. Circ Res 102(10):1239–1246
Brivio D, Zygmanski P, Arnoldussen M, Hanlon J, Chell E, Sajo E, Makrigiorgos G, Ngwa W (2015) Kilovoltage radiosurgery with gold nanoparticles for neovascular age-related macular degeneration (AMD): a Monte Carlo evaluation. Phys Med Biol 60(24):9203
Cagri A, Ustunol Z, Ryser ET (2004) Antimicrobial edible films and coatings. J Food Prot 67(4):833–848
Cartiera MS, Ferreira EC, Caputo C, Egan ME, Caplan MJ, Saltzman WM (2009) Partial correction of cystic fibrosis defects with PLGA nanoparticles encapsulating curcumin. Mol Pharm 7(1):86–93
Cascone MG, Lazzeri L, Carmignani C, Zhu Z (2002) Gelatin nanoparticles produced by a simple W/O emulsion as delivery system for methotrexate. J Mater Sci Mater Med 13(5):523–526
Cha DS, Chinnan MS (2004) Biopolymer-based antimicrobial packaging: a review. Crit Rev Food Sci Nutr 44(4):223–237
Chartuprayoon N, Rheem Y, Chen W, Myung N (2010) Detection of plant pathogen using LPNE grown single conducting polymer nanoribbon. In: Meeting abstracts, vol 40. The Electrochemical Society, Pennington, NJ, pp 2278–2278
Chaudhry Q, Scotter M, Blackburn J, Ross B, Boxall A, Castle L, Aitken R, Watkins R (2008) Applications and implications of nanotechnologies for the food sector. Food Addit Contam 25(3):241–258
Chellat F, Merhi Y, Moreau A, Yahia LH (2005) Therapeutic potential of nanoparticulate systems for macrophage targeting. Biomaterials 26(35):7260–7275
Cheng X, Murphy W, Recek N, Yan D, Cvelbar U, Vesel A, Mozetič M, Canady J, Keidar M, Sherman JH (2014) Synergistic effect of gold nanoparticles and cold plasma on glioblastoma cancer therapy. J Phys D Appl Phys 47(33):335402
Choi HS, Ipe BI, Misra P, Lee JH, Bawendi MG, Frangioni JV (2009) Tissue-and organ-selective biodistribution of NIR fluorescent quantum dots. Nano Lett 9(6):2354–2359
Corot C, Petry KG, Trivedi R, Saleh A, Jonkmanns C, Le Bas J-F, Blezer E, Rausch M, Brochet B, Foster-Gareau P (2004) Macrophage imaging in central nervous system and in carotid atherosclerotic plaque using ultrasmall superparamagnetic iron oxide in magnetic resonance imaging. Investig Radiol 39(10):619–625
Corot C, Robert P, Idée J-M, Port M (2006) Recent advances in iron oxide nanocrystal technology for medical imaging. Adv Drug Deliv Rev 58(14):1471–1504
Couzin J (2002) Small RNAs make big splash. American Association for the Advancement of Science, Washington, DC
Croce K, Gao H, Wang Y, Mooroka T, Sakuma M, Shi C, Sukhova GK, Packard RR, Hogg N, Libby P (2009) Myeloid-related protein-8/14 is critical for the biological response to vascular injury. Circulation 120(5):427–436
Dalal V, Sharma NK, Biswas S (2017) Oxidative stress: diagnostic methods and application in medical science. In: Oxidative stress: diagnostic methods and applications in medical science. Springer, New York, NY, pp 23–45
de Jong WH, Roszek B, Geertsma RE (2005) Nanotechnology in medical applications: possible risks for human health. RIVM report 265001002/2005. RIVM Rep 2005:1–46
De la Fuente JM, Alcantara D, Eaton P, Crespo P, Rojas TC, Fernandez A, Hernando A, Penades S (2006) Gold and gold – iron oxide magnetic glyconanoparticles: synthesis, characterization and magnetic properties. J Phys Chem B 110(26):13021–13028
Deng Z, Liu Y, Liu C, Xiang X, Wang J, Cheng Z, Shah SV, Zhang S, Zhang L, Zhuang X (2009) Immature myeloid cells induced by a high-fat diet contribute to liver inflammation. Hepatology 50(5):1412–1420
Dhillon N, Wolff R, Abbruzzese J, Hong D, Camacho L, Li L, Braiteh F, Kurzrock R (2006) Phase II clinical trial of curcumin in patients with advanced pancreatic cancer. J Clin Oncol 24(18S):14151–14151
Dillen K, Vandervoort J, Van den Mooter G, Ludwig A (2006) Evaluation of ciprofloxacin-loaded Eudragit® RS100 or RL100/PLGA nanoparticles. Int J Pharm 314(1):72–82
Doane TL, Burda C (2012) The unique role of nanoparticles in nanomedicine: imaging, drug delivery and therapy. Chem Soc Rev 41(7):2885–2911
Dobson J (2006) Magnetic nanoparticles for drug delivery. Drug Dev Res 67(1):55–60
Doyle ME (2006) Nanotechnology: a brief literature review. Food Research Institute, UW-Madison, Madison, WI
Duncan R (2003) The dawning era of polymer therapeutics. Nat Rev Drug Discov 2(5):347–360
Durán N, Marcato PD, Durán M, Yadav A, Gade A, Rai M (2011) Mechanistic aspects in the biogenic synthesis of extracellular metal nanoparticles by peptides, bacteria, fungi, and plants. Appl Microbiol Biotechnol 90(5):1609–1624
Elbashir SM, Harborth J, Lendeckel W, Yalcin A, Weber K, Tuschl T (2001) Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells. Nature 411(6836):494
EPA U (2008) Nanotechnology for site remediation fact sheet. EPA, Zeist
Feng X, Chen A, Zhang Y, Wang J, Shao L, Wei L (2015) Central nervous system toxicity of metallic nanoparticles. Int J Nanomedicine 10:4321
Ferrari M (2005) Cancer nanotechnology: opportunities and challenges. Nat Rev Cancer 5(3):161
Firestein GS (2003) Evolving concepts of rheumatoid arthritis. Nature 423(6937):356
Fox RF, Choi MH (2001) Rectified Brownian motion and kinesin motion along microtubules. Phys Rev E 63(5):051901
Fujisawa H, Nishimura T, Inoue Y, Ogaya S, Shibata Y, Nakagawa Y, Sato S, Kimura K (1990) Antiinflammatory properties of the new antirheumatic agent 4-acetylaminophenylacetic acid. Arzneimittelforschung 40(6):693–697
Fujisawa H, Nishimura T, Motonaga A, Inoue Y, Inoue K, Suzuka H, Yoshifusa H, Kimura K, Muramatsu M (1994) Effect of actarit on type II collagen-induced arthritis in mice. Arzneimittelforschung 44(1):64–68
Gaharwar AK, Peppas NA, Khademhosseini A (2014) Nanocomposite hydrogels for biomedical applications. Biotechnol Bioeng 111(3):441–453
Garinot M, Fiévez V, Pourcelle V, Stoffelbach F, des Rieux A, Plapied L, Theate I, Freichels H, Jérôme C, Marchand-Brynaert J (2007) PEGylated PLGA-based nanoparticles targeting M cells for oral vaccination. J Control Release 120(3):195–204
Ghosh P, Han G, De M, Kim CK, Rotello VM (2008) Gold nanoparticles in delivery applications. Adv Drug Deliv Rev 60(11):1307–1315
Giljohann DA, Seferos DS, Daniel WL, Massich MD, Patel PC, Mirkin CA (2010) Gold nanoparticles for biology and medicine. Angew Chem Int Ed 49(19):3280–3294
Gref R, Minamitake Y, Peracchia MT, Trubetskoy V, Torchilin V, Langer R (1994) Biodegradable long-circulating polymeric nanospheres. Science 263(5153):1600–1603
Guan H, Chi D, Yu J, Li H (2010) Dynamics of residues from a novel nano-imidacloprid formulation in soyabean fields. Crop Prot 29(9):942–946
Hainfeld JF, Slatkin DN, Smilowitz HM (2004) The use of gold nanoparticles to enhance radiotherapy in mice. Phys Med Biol 49(18):N309
Haynes B, Zhang Y, Liu F, Li J, Petit S, Kothayer H, Bao X, Westwell AD, Mao G, Shekhar MP (2016) Gold nanoparticle conjugated Rad6 inhibitor induces cell death in triple negative breast cancer cells by inducing mitochondrial dysfunction and PARP-1 hyperactivation: synthesis and characterization. Nanomedicine 12(3):745–757
Henn KW, Waddill DW (2006) Utilization of nanoscale zero-valent iron for source remediation – a case study. Remediation 16(2):57–77
Higaki M, Ishihara T, Izumo N, Takatsu M, Mizushima Y (2005) Treatment of experimental arthritis with poly (D,L-lactic/glycolic acid) nanoparticles encapsulating betamethasone sodium phosphate. Ann Rheum Dis 64(8):1132–1136
Horisawa E, Hirota T, Kawazoe S, Yamada J, Yamamoto H, Takeuchi H, Kawashima Y (2002a) Prolonged anti-inflammatory action of DL-lactide/glycolide copolymer nanospheres containing betamethasone sodium phosphate for an intra-articular delivery system in antigen-induced arthritic rabbit. Pharm Res 19(4):403–410
Horisawa E, Kubota K, Tuboi I, Sato K, Yamamoto H, Takeuchi H, Kawashima Y (2002b) Size-dependency of DL-lactide/glycolide copolymer particulates for intra-articular delivery system on phagocytosis in rat synovium. Pharm Res 19(2):132–139
Howard KA, Paludan SR, Behlke MA, Besenbacher F, Deleuran B, Kjems J (2009) Chitosan/siRNA nanoparticle-mediated TNF-α knockdown in peritoneal macrophages for anti-inflammatory treatment in a murine arthritis model. Mol Ther 17(1):162–168
Ikai A, Idiris A, Sekiguchi H, Arakawa H, Nishida S (2002) Intra-and intermolecular mechanics of proteins and polypeptides studied by AFM: with applications. Appl Surf Sci 188(3–4):506–512
Ikoba U, Peng H, Li H, Miller C, Yu C, Wang Q (2015) Nanocarriers in therapy of infectious and inflammatory diseases. Nanoscale 7(10):4291–4305
Irani S, Shahmirani Z, Atyabi SM, Mirpoor S (2015) Induction of growth arrest in colorectal cancer cells by cold plasma and gold nanoparticles. Arch Med Sci 11(6):1286
Ishijima A, Yanagida T (2001) Single molecule nanobioscience. Trends Biochem Sci 26(7):438–444
Ishrat M, Nayik GA, Dar SM, Nanda V (2018) Novel food packaging technologies: Innovations and future prospective. Journal of the Saudi Society of Agricultural Sciences 17(4):454–462
Iwamoto S, S-i I, Tsujiyama K, Kurahashi C, Takeshita K, Naoe M, Masunaga A, Ogawa Y, Oguchi K, Miyazaki A (2007) TNF-α drives human CD14+ monocytes to differentiate into CD70+ dendritic cells evoking Th1 and Th17 responses. J Immunol 179(3):1449–1457
Jain KK (2012) Nanobiotechnology-based strategies for crossing the blood–brain barrier. Nanomedicine 7(8):1225–1233
Jiang Z, Sun S, Liang A, Huang W, Qin A (2006) Gold-labeled nanoparticle-based immunoresonance scattering spectral assay for trace apolipoprotein AI and apolipoprotein B. Clin Chem 52(7):1389–1394
Jongstra-Bilen J, Haidari M, Zhu S-N, Chen M, Guha D, Cybulsky MI (2006) Low-grade chronic inflammation in regions of the normal mouse arterial intima predisposed to atherosclerosis. J Exp Med 203(9):2073–2083
Ju HW, Lee OJ, Lee JM, Moon BM, Park HJ, Park YR, Lee MC, Kim SH, Chao JR, Ki CS (2016) Wound healing effect of electrospun silk fibroin nanomatrix in burn-model. Int J Biol Macromol 85:29–39
Kalita S, Kandimalla R, Sharma KK, Kataki AC, Deka M, Kotoky J (2016) Amoxicillin functionalized gold nanoparticles reverts MRSA resistance. Mater Sci Eng C 61:720–727
Kang T-F, Wang F, Lu L-P, Zhang Y, Liu T-S (2010) Methyl parathion sensors based on gold nanoparticles and Nafion film modified glassy carbon electrodes. Sensors Actuators B Chem 145(1):104–109
Khoobchandani M, Katti K, Maxwell A, Fay WP, Katti KV (2016) Laminin receptor-avid nanotherapeutic EGCg-AuNPs as a potential alternative therapeutic approach to prevent restenosis. Int J Mol Sci 17(3):316
Khoury M, Louis-Plence P, Escriou V, Noel D, Largeau C, Cantos C, Scherman D, Jorgensen C, Apparailly F (2006) Efficient new cationic liposome formulation for systemic delivery of small interfering RNA silencing tumor necrosis factor α in experimental arthritis. Arthritis Rheum 54(6):1867–1877
Kumari A, Yadav SK, Yadav SC (2010) Biodegradable polymeric nanoparticles based drug delivery systems. Colloids Surf B: Biointerfaces 75(1):1–18
Kusunoki N, Yamazaki R, Kawai S (2008) Pro-apoptotic effect of nonsteroidal anti-inflammatory drugs on synovial fibroblasts. Mod Rheumatol 18(6):542–551
Kwatra D, Venugopal A, Anant S (2013) Nanoparticles in radiation therapy: a summary of various approaches to enhance radiosensitization in cancer. Transl Cancer Res 2(4):330–342
Lai S-F, Ko B-H, Chien C-C, Chang C-J, Yang S-M, Chen H-H, Petibois C, Hueng D-Y, Ka S-M, Chen A (2015) Gold nanoparticles as multimodality imaging agents for brain gliomas. J Nanobiotechnol 13(1):85
Lamprecht A, Schäfer U, Lehr C-M (2001a) Size-dependent bioadhesion of micro-and nanoparticulate carriers to the inflamed colonic mucosa. Pharm Res 18(6):788–793
Lamprecht A, Ubrich N, Yamamoto H, Schäfer U, Takeuchi H, Maincent P, Kawashima Y, Lehr C-M (2001b) Biodegradable nanoparticles for targeted drug delivery in treatment of inflammatory bowel disease. J Pharmacol Exp Ther 299(2):775–781
Lamprecht A, Yamamoto H, Takeuchi H, Kawashima Y (2005) Nanoparticles enhance therapeutic efficiency by selectively increased local drug dose in experimental colitis in rats. J Pharmacol Exp Ther 315(1):196–202
Lavan DA, McGuire T, Langer R (2003) Small-scale systems for in vivo drug delivery. Nat Biotechnol 21(10):1184
Lee SJ-A, Kavanaugh A (2003) Pharmacological treatment of established rheumatoid arthritis. Clin Rheumatol 17(5):811–829
Lee M-Y, Yang J-A, Jung HS, Beack S, Choi JE, Hur W, Koo H, Kim K, Yoon SK, Hahn SK (2012a) Hyaluronic acid–gold nanoparticle/interferon α complex for targeted treatment of hepatitis C virus infection. ACS Nano 6(11):9522–9531
Lee S-M, Kim HJ, Ha Y-J, Park YN, Lee S-K, Park Y-B, Yoo K-H (2012b) Targeted chemo-photothermal treatments of rheumatoid arthritis using gold half-shell multifunctional nanoparticles. ACS Nano 7(1):50–57
Lee H, Lee M-Y, Bhang SH, Kim B-S, Kim YS, Ju JH, Kim KS, Hahn SK (2014) Hyaluronate–gold nanoparticle/tocilizumab complex for the treatment of rheumatoid arthritis. ACS Nano 8(5):4790–4798
Liu J, Levine AL, Mattoon JS, Yamaguchi M, Lee RJ, Pan X, Rosol TJ (2006) Nanoparticles as image enhancing agents for ultrasonography. Phys Med Biol 51(9):2179
Liu S, Yuan L, Yue X, Zheng Z, Tang Z (2008) Recent advances in nanosensors for organophosphate pesticide detection. Adv Powder Technol 19(5):419–441
Lopez-Rubio A, Gavara R, Lagaron JM (2006) Bioactive packaging: turning foods into healthier foods through biomaterials. Trends Food Sci Technol 17(10):567–575
López MM, Llop P, Olmos A, Marco-Noales E, Cambra M, Bertolini E (2009) Are molecular tools solving the challenges posed by detection of plant pathogenic bacteria and viruses? Curr Issues Mol Biol 11(1):13
Lower SK, Hochella MF, Beveridge TJ (2001) Bacterial recognition of mineral surfaces: nanoscale interactions between Shewanella and α-FeOOH. Science 292(5520):1360–1363
Lyons K, Scrinis G (2009) Under the regulatory radar? Nanotechnologies and their impacts for rural Australia. Tracking rural change: community, policy and technology in Australia, New Zealand and Europe. Australian National University E Press, Canberra, ACT, pp 151–171
Makino H, Yoshinaga Y, Yamasaki Y, Morita Y, Hashimoto H, Yamamura M (2002) Renal involvement in rheumatoid arthritis: analysis of renal biopsy specimens from 100 patients. Mod Rheumatol 12(2):148–154
Matsubara T (1999) The basic and clinical use of DMARDs. Rheumatology 22:81–97
McQuaid HN, Muir MF, Taggart LE, McMahon SJ, Coulter JA, Hyland WB, Jain S, Butterworth KT, Schettino G, Prise KM (2016) Imaging and radiation effects of gold nanoparticles in tumour cells. Sci Rep 6:19442
Meissner Y, Lamprecht A (2008) Alternative drug delivery approaches for the therapy of inflammatory bowel disease. J Pharm Sci 97(8):2878–2891
Miller G, Senjen R (2008) Out of the laboratory and onto our plates: nanotechnology in food and agriculture. A report prepared for Friends of the Earth Australia. Friends of the Earth Europe and Friends of the Earth United States and supported by Friends of the Earth Germany Friends of the Earth Australia Nanotechnology Project, Australia
Moghimi SM, Hunter AC, Murray JC (2001) Long-circulating and target-specific nanoparticles: theory to practice. Pharmacol Rev 53(2):283–318
Moghimi SM, Hunter AC, Murray JC (2005) Nanomedicine: current status and future prospects. FASEB J 19(3):311–330
Mohs AM, Provenzale JM (2010) Applications of nanotechnology to imaging and therapy of brain tumors. Neuroimaging Clin N Am 20(3):283–292
Moravej M, Mantovani D (2011) Biodegradable metals for cardiovascular stent application: interests and new opportunities. Int J Mol Sci 12(7):4250–4270
Morillon V, Debeaufort F, Blond G, Capelle M, Voilley A (2002) Factors affecting the moisture permeability of lipid-based edible films: a review. Crit Rev Food Sci Nutr 42(1):67–89
Morris V (2007) Nanotechnology and food. IUFoST scientific information bulletin. IUFoST–2007-7, Oakville, ON
Morris AW, Sharp MM, Albargothy NJ, Fernandes R, Hawkes CA, Verma A, Weller RO, Carare RO (2016) Vascular basement membranes as pathways for the passage of fluid into and out of the brain. Acta Neuropathol 131(5):725–736
Mu H, Guo F, Niu H, Liu Q, Wang S, Duan J (2014) Chitosan improves anti-biofilm efficacy of gentamicin through facilitating antibiotic penetration. Int J Mol Sci 15(12):22296–22308
Müller DJ, Janovjak H, Lehto T, Kuerschner L, Anderson K (2002) Observing structure, function and assembly of single proteins by AFM. Prog Biophys Mol Biol 79(1–3):1–43
Naraginti S, Kumari PL, Das RK, Sivakumar A, Patil SH, Andhalkar VV (2016) Amelioration of excision wounds by topical application of green synthesized, formulated silver and gold nanoparticles in albino Wistar rats. Mater Sci Eng C 62:293–300
Narayanan NK, Nargi D, Randolph C, Narayanan BA (2009) Liposome encapsulation of curcumin and resveratrol in combination reduces prostate cancer incidence in PTEN knockout mice. Int J Cancer 125(1):1–8
Pankhurst QA, Connolly J, Jones S, Dobson J (2003) Applications of magnetic nanoparticles in biomedicine. J Phys D Appl Phys 36(13):R167
Parham H, Rahbar N (2010) Square wave voltammetric determination of methyl parathion using ZrO2-nanoparticles modified carbon paste electrode. J Hazard Mater 177(1–3):1077–1084
Park JS, Yang HN, Jeon SY, Woo DG, Kim MS, Park K-H (2012) The use of anti-COX2 siRNA coated onto PLGA nanoparticles loading dexamethasone in the treatment of rheumatoid arthritis. Biomaterials 33(33):8600–8612
Pérez-Campaña C, Gómez-Vallejo V, Puigivila M, Martín A, Calvo-Fernández T, Moya SE, Ziolo RF, Reese T, Llop J (2013) Biodistribution of different sized nanoparticles assessed by positron emission tomography: a general strategy for direct activation of metal oxide particles. ACS Nano 7(4):3498–3505
Pittet MJ, Swirski FK, Reynolds F, Josephson L, Weissleder R (2006) Labeling of immune cells for in vivo imaging using magnetofluorescent nanoparticles. Nat Protoc 1(1):73
Poon W, Zhang X, Bekah D, Teodoro JG, Nadeau JL (2015) Targeting B16 tumors in vivo with peptide-conjugated gold nanoparticles. Nanotechnology 26(28):285101
Prasad R, Aranda E (2018) Approaches in bioremediation: the new era of environmental microbiology and nanobiotechnology. Springer International Publishing (978-3-030-02369-0). https://www.springer.com/gp/book/9783030023683
Prasad R, Kumar V, Kumar M (2017a) Nanotechnology: food and environmental paradigm. Springer Nature Singapore Pte Ltd. (ISBN 978-981-10-4678-0)
Prasad R, Kumar M, Kumar V (2017b) Nanotechnology: an agriculture paradigm. Springer Nature Singapore Pte Ltd. (ISBN: 978-981-10-4573-8)
Prasad R, Bhattacharyya A, Nguyen QD (2017c) Nanotechnology in sustainable agriculture: recent developments, challenges, and perspectives. Front Microbiol 8:1014. doi: 10.3389/fmicb.2017.01014
Prasad R, Kumar V, Prasad KS (2017d) Nanotechnology in sustainable agriculture: present concerns and future aspects. Afr J Biotechnol 13(6):705–713
Qu P, Du H, Li Y, Yan C (2009) Myeloid-specific expression of Api6/AIM/Spα induces systemic inflammation and adenocarcinoma in the lung. J Immunol 182(3):1648–1659
Ramesh GV, Kodiyath R, Tanabe T, Manikandan M, Fujita T, Matsumoto F, Ishihara S, Ueda S, Yamashita Y, Ariga K (2014) NbPt3 intermetallic nanoparticles: highly stable and CO-tolerant electrocatalyst for fuel oxidation. ChemElectroChem 1(4):728–732
Ravichandran R (2010) Nanotechnology applications in food and food processing: innovative green approaches, opportunities and uncertainties for global market. Int J Green Nanotechnol Phys Chem 1(2):P72–P96
Ravindran J, Prasad S, Aggarwal BB (2009) Curcumin and cancer cells: how many ways can curry kill tumor cells selectively? AAPS J 11(3):495–510
Reynolds G (2007) FDA recommends nanotechnology research, but not labeling. Food Prod Daily News 26
Rhim J-W (2004) Increase in water vapor barrier property of biopolymer-based edible films and coatings by compositing with lipid materials. Food Sci Biotechnol 13(4):528–535
Roco MC, Williams RS, Alivisatos P (2000) Nanotechnology research directions: IWGN workshop report: vision for nanotechnology in the next decade. Springer, New York, NY
Rogers-Hayden T, Pidgeon N (2007) Moving engagement “upstream”? Nanotechnologies and the Royal Society and Royal Academy of Engineering’s inquiry. Public Underst Sci 16(3):345–364
Saag KG, Teng GG, Patkar NM, Anuntiyo J, Finney C, Curtis JR, Paulus HE, Mudano A, Pisu M, Elkins-Melton M (2008) American College of Rheumatology 2008 recommendations for the use of nonbiologic and biologic disease-modifying antirheumatic drugs in rheumatoid arthritis. Arthritis Care Res 59(6):762–784
Saleh N, Sirk K, Liu Y, Phenrat T, Dufour B, Matyjaszewski K, Tilton RD, Lowry GV (2007) Surface modifications enhance nanoiron transport and NAPL targeting in saturated porous media. Environ Eng Sci 24(1):45–57
Sasidharan A, Monteiro-Riviere NA (2015) Biomedical applications of gold nanomaterials: opportunities and challenges. Wiley Interdiscip Rev Nanomed Nanobiotechnol 7(6):779–796
Schalnus R (2003) Topical nonsteroidal anti-inflammatory therapy in ophthalmology. Ophthalmologica 217(2):89–98
Schiffelers RM, Xu J, Storm G, Woodle MC, Scaria PV (2005) Effects of treatment with small interfering RNA on joint inflammation in mice with collagen-induced arthritis. Arthritis Rheum 52(4):1314–1318
Schmidt C, Collnot EM, Bojarski C, Schumann M, Schulzke JD, Lehr CM, Stallmach A (2010) W1266 confocal laser endomicroscopy (CLE) reveals mucosal accumulation of PLGA-nanoparticles in ulcerous lesions of patients with inflammatory bowel diseases. Gastroenterology 138(5):S-687
Schnabel A, Gross WL (1994) Low-dose methotrexate in rheumatic diseases - efficacy, side effects, and risk factors for side effects. In: Seminars in arthritis and rheumatism, 1994, vol 5. Elsevier, Amsterdam, pp 310–327
Senyei A, Widder K, Czerlinski G (1978) Magnetic guidance of drug-carrying microspheres. J Appl Phys 49(6):3578–3583
Shilo M, Reuveni T, Motiei M, Popovtzer R (2012) Nanoparticles as computed tomography contrast agents: current status and future perspectives. Nanomedicine 7(2):257–269
Shilo M, Sharon A, Baranes K, Motiei M, Lellouche J-PM, Popovtzer R (2015) The effect of nanoparticle size on the probability to cross the blood-brain barrier: an in-vitro endothelial cell model. J Nanobiotechnol 13(1):19–25
Simon T, Tomuleasa C, Bojan A, Berindan-Neagoe I, Boca S, Astilean S (2015) Design of FLT3 inhibitor-gold nanoparticle conjugates as potential therapeutic agents for the treatment of acute myeloid leukemia. Nanoscale Res Lett 10(1):466
Singh S, Singh M, Agrawal VV, Kumar A (2010) An attempt to develop surface plasmon resonance based immunosensor for Karnal bunt (Tilletia indica) diagnosis based on the experience of nano-gold based lateral flow immuno-dipstick test. Thin Solid Films 519(3):1156–1159
Singh S, Kumar V, Dhanjal DS, Datta S, Prasad R, Singh J (2020) Biological biosensors for monitoring and diagnosis. In: Singh J, Vyas A, Wang S, Prasad R (eds) Microbial biotechnology: basic research and applications. Springer Nature Singapore, pp 317–336
Smalley R (2002) Nanotechnology: the wet/dry frontier. In: Proceedings of the small wonders workshop, Washington DC
Soehnlein O, Weber C (2009) Myeloid cells in atherosclerosis: initiators and decision shapers. In: Seminars in immunopathology, 2009, vol 1. Springer, New York, NY, pp 35–47
Sridhar S, Venugopal JR, Sridhar R, Ramakrishna S (2015) Cardiogenic differentiation of mesenchymal stem cells with gold nanoparticle loaded functionalized nanofibers. Colloids Surf B: Biointerfaces 134:346–354
Sugihara K, Morino A, Nomura A, Iida S, Sugiyama M (1990) Pharmacokinetics of 4-acetylaminophenylacetic acid. 1st communication: absorption, distribution, metabolism and excretion in mice, rats, dogs and monkeys after single administration of 14C-labeled compound. Arzneimittelforschung 40(7):800–805
Sul O-J, Kim J-C, Kyung T-W, Kim H-J, Kim Y-Y, Kim S-H, Kim J-S, Choi H-S (2010) Gold nanoparticles inhibited the receptor activator of nuclear factor-κb ligand (RANKL)-induced osteoclast formation by acting as an antioxidant. Biosci Biotechnol Biochem 74(11):2209–2213
Sun D, Zhuang X, Xiang X, Liu Y, Zhang S, Liu C, Barnes S, Grizzle W, Miller D, Zhang H-G (2010) A novel nanoparticle drug delivery system: the anti-inflammatory activity of curcumin is enhanced when encapsulated in exosomes. Mol Ther 18(9):1606–1614
Taylor E, Megson I, Haslett C, Rossi A (2003) Nitric oxide: a key regulator of myeloid inflammatory cell apoptosis. Cell Death Differ 10(4):418
Thakor A, Jokerst J, Zavaleta C, Massoud T, Gambhir S (2011) Gold nanoparticles: a revival in precious metal administration to patients. Nano Lett 11(10):4029–4036
Thurn KT, Brown E, Wu A, Vogt S, Lai B, Maser J, Paunesku T, Woloschak GE (2007) Nanoparticles for applications in cellular imaging. Nanoscale Res Lett 2(9):430
Trantyek P, Johnson R (2006) Nanotechnologies for environmental cleanup. Nanotoday 1:44–48
Tsai CY, Shiau AL, Chen SY, Chen YH, Cheng PC, Chang MY, Chen DH, Chou CH, Wang CR, Wu CL (2007) Amelioration of collagen-induced arthritis in rats by nanogold. Arthritis Rheum 56(2):544–554
Vamvakaki V, Chaniotakis NA (2007) Pesticide detection with a liposome-based nano-biosensor. Biosens Bioelectron 22(12):2848–2853
Van Dyk JS, Pletschke B (2011) Review on the use of enzymes for the detection of organochlorine, organophosphate and carbamate pesticides in the environment. Chemosphere 82(3):291–307
Van Ede AE, Laan RF, Blom HJ, De Abreu RA, van de Putte LB (1998) Methotrexate in rheumatoid arthritis: an update with focus on mechanisms involved in toxicity. In: Seminars in arthritis and rheumatism, 1998, vol 5. Elsevier, Amsterdam, pp 277–292
Vega E, Gamisans F, Garcia M, Chauvet A, Lacoulonche F, Egea M (2008) PLGA nanospheres for the ocular delivery of flurbiprofen: drug release and interactions. J Pharm Sci 97(12):5306–5317
Vij N, Min T, Marasigan R, Belcher CN, Mazur S, Ding H, Yong K-T, Roy I (2010) Development of PEGylated PLGA nanoparticle for controlled and sustained drug delivery in cystic fibrosis. J Nanobiotechnol 8(1):22
Volkova N, Yukhta M, Pavlovich O, Goltsev A (2016) Application of cryopreserved fibroblast culture with Au nanoparticles to treat burns. Nanoscale Res Lett 11(1):22
Wang Z, Wei F, Liu S-Y, Xu Q, Huang J-Y, Dong X-Y, Yu J-H, Yang Q, Zhao Y-D, Chen H (2010) Electrocatalytic oxidation of phytohormone salicylic acid at copper nanoparticles-modified gold electrode and its detection in oilseed rape infected with fungal pathogen Sclerotinia sclerotiorum. Talanta 80(3):1277–1281
Wesley SJ, Raja P, Raj A, Tiroutchelvamae D (2014) Review on-nanotechnology applications in food packaging and safety. Int J Eng Res 3(11):645–651
Wickline SA, Neubauer AM, Winter PM, Caruthers SD, Lanza GM (2007) Molecular imaging and therapy of atherosclerosis with targeted nanoparticles. J Magn Reson Imaging 25(4):667–680
Xing Y, Zhao J, Conti PS, Chen K (2014) Radiolabeled nanoparticles for multimodality tumor imaging. Theranostics 4(3):290
Yan J, Huang K, Wang Y, Liu S (2005) Study on anti-pollution nano-preparation of dimethomorph and its performance. Chin Sci Bull 50(2):108–112
Yang Y, Zhang L, Cai J, Li X, Cheng D, Su H, Zhang J, Liu S, Shi H, Zhang Y (2016) Tumor angiogenesis targeted radiosensitization therapy using gold nanoprobes guided by MRI/SPECT imaging. ACS Appl Mater Interfaces 8(3):1718–1732
Yao KS, Li S, Tzeng K, Cheng TC, Chang CY, Chiu C, Liao C, Hsu J, Lin Z (2009) Fluorescence silica nanoprobe as a biomarker for rapid detection of plant pathogens. Ad Mater Res Trans Tech Publ, In, pp 513–516
Ye J, Wang Q, Zhou X, Zhang N (2008) Injectable actarit-loaded solid lipid nanoparticles as passive targeting therapeutic agents for rheumatoid arthritis. Int J Pharm 352(1–2):273–279
Yoshida H (1987) Effect of MS-932 (4-acetylaminophenylacetic acid) on articular lesions in MRL/1 mice. Int J Immunother 4:261–264
Zhan Y, Zeng W, Jiang G, Wang Q, Shi X, Zhou Z, Deng H, Du Y (2015) Construction of lysozyme exfoliated rectorite-based electrospun nanofibrous membranes for bacterial inhibition. J Appl Polym Sci 132(8):41496
Zhang W (2005) Nano technology for water purification and waste treatment. Front Nanotechnol, US EPA millennium lecture series
Zhang WX, Elliott DW (2006) Applications of iron nanoparticles for groundwater remediation. Remediat J 16(2):7–21
Zhang W, Prausnitz MR, Edwards A (2004) Model of transient drug diffusion across cornea. J Control Release 99(2):241–258
Zheng L, Hong F, Lu S, Liu C (2005) Effect of nano-TiO2 on strength of naturally aged seeds and growth of spinach. Biol Trace Elem Res 104(1):83–91
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2020 Springer Nature Switzerland AG
About this chapter
Cite this chapter
Dalal, V., Biswas, S. (2020). Nanoscience: Convergence with Biomedical and Biological Applications. In: Thangadurai, D., Sangeetha, J., Prasad, R. (eds) Functional Bionanomaterials. Nanotechnology in the Life Sciences. Springer, Cham. https://doi.org/10.1007/978-3-030-41464-1_1
Download citation
DOI: https://doi.org/10.1007/978-3-030-41464-1_1
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-030-41463-4
Online ISBN: 978-3-030-41464-1
eBook Packages: Biomedical and Life SciencesBiomedical and Life Sciences (R0)