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Obesity and Its Complications Pathogenesis

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Pathophysiology of Obesity-Induced Health Complications

Part of the book series: Advances in Biochemistry in Health and Disease ((ABHD,volume 19))

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Abstract

Obesity became an epidemic public health problem and continuously increasing every year. For the longest time, the pathologic framework for obesity had been simple: caloric intake is greater than the energy output, which by far still true, however, the underlying reasons for increased energy intake and reduced energy expenditure remain largely unknown. Emerging data indicate that obesity can be oftentimes secondary to an underlying pathology, which can be due to genetics, inflammation, microbiome dysbiosis, metabolism, drugs and several other reasons. In this chapter, we described the pathology of obesity and underlying factors are linked or contributing in its progression.

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Authors and Affiliations

  1. Department of Internal Medicine-Molecular Medicine, Wake Forest School of Medicine, Winston-Salem, NC, 27101, USA

    Isabella So & Hariom Yadav

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  1. Isabella So
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  2. Hariom Yadav
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Correspondence to Hariom Yadav .

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Editors and Affiliations

  1. Asper Clinical Research Institute and Office of Clinical Research, St. Boniface Hospital, Winnipeg, MB, Canada

    Paramjit S. Tappia

  2. Asper Clinical Research Institute and Office of Clinical Research, St. Boniface Hospital, Winnipeg, MB, Canada

    Bram Ramjiawan

  3. Institute of Cardiovascular Sciences, St. Boniface Hospital Albrechtsen Research Centre, Winnipeg, MB, Canada

    Naranjan S. Dhalla

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So, I., Yadav, H. (2020). Obesity and Its Complications Pathogenesis. In: Tappia, P., Ramjiawan, B., Dhalla, N. (eds) Pathophysiology of Obesity-Induced Health Complications. Advances in Biochemistry in Health and Disease, vol 19. Springer, Cham. https://doi.org/10.1007/978-3-030-35358-2_3

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