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Acute Complications of Inflammatory Bowel Disease

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The SAGES Manual of Acute Care Surgery

Abstract

Inflammatory bowel disease (IBD) poses a challenging problem for the general surgeon. Despite advances in medical management, ulcerative colitis (UC) and Crohn’s disease (CD) often present with acute and emergent surgical issues. Surgical intervention is generally reserved for failed medical therapy or complications of the disease. The complications that may require urgent surgical intervention include hemorrhage, acute severe colitis, perforation, obstruction, abscess, and fistula disease. For patients with colonic emergencies, an abdominal colectomy with end ileostomy is recommended. Laparoscopy can be safe and beneficial in IBD patients and should be considered in the emergency setting.

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References

  1. Modigliani R, Mary J-Y, Simon J-F, et al. Clinical, biological, and endoscopic picture of attacks of Crohn’s disease. Gastroenterology. 1990;98(4):811–8.

    Article  CAS  Google Scholar 

  2. Turner D, Walsh CM, Steinhart AH, Griffiths AM. Response to corticosteroids in severe ulcerative colitis: a systematic review of the literature and a meta-regression. Clin Gastroenterol Hepatol. 2007;5(1):103–10.

    Article  CAS  Google Scholar 

  3. Burger D, Travis S. Conventional medical management of inflammatory bowel disease. Gastroenterology. 2011;140(6):1827–1837.e2.

    Article  Google Scholar 

  4. Munkholm P, Langholz E, Davidsen M, Binder V. Frequency of glucocorticoid resistance and dependency in Crohn’s disease. Gut. 1994;35(3):360–2.

    Article  CAS  Google Scholar 

  5. Razack R, Seidner DL. Nutrition in inflammatory bowel disease. Curr Opin Gastroenterol. 2007;23(4):400–5.

    Article  Google Scholar 

  6. Sharma A, Chinn BT. Preoperative optimization of crohn disease. Clin Colon Rectal Surg. 2013;26(2):75–9.

    Article  Google Scholar 

  7. Suding P. Definitive risk factors for anastomotic leaks in elective open colorectal resection. Arch Surg. 2008;143(9):907.

    Article  Google Scholar 

  8. Telem DA. Risk factors for anastomotic leak following colorectal surgery. Arch Surg. 2010;145(4):371.

    Article  Google Scholar 

  9. Strong S, Steele SR, Boutrous M, et al. Clinical practice guideline for the surgical management of Crohn’s disease. Dis Colon Rectum. 2015;58(11):1021–36.

    Article  Google Scholar 

  10. Kim K-J, Han BJ, Yang S-K, et al. Risk factors and outcome of acute severe lower gastrointestinal bleeding in Crohn’s disease. Dig Liver Dis. 2012;44(9):723–8.

    Article  Google Scholar 

  11. Robert JR, Sachar DB, Greenstein AJ. Severe gastrointestinal hemorrhage in Crohnʼs disease. Ann Surg. 1991;213(3):207–11.

    Article  CAS  Google Scholar 

  12. Ross H, Steele SR, Varma M, et al. Practice parameters for the surgical treatment of ulcerative colitis. Dis Colon Rectum. 2014;57(1):5–22.

    Article  Google Scholar 

  13. Strong SA. Management of acute colitis and toxic megacolon. Clin Colon Rectal Surg. 2010;23(4):274–84.

    Article  Google Scholar 

  14. Grieco MB, Bordan DL, Geiss AC, Beil AR Jr. Toxic megacolon complicating Crohn’s colitis. Ann Surg. 1980;191(1):75–80.

    Article  CAS  Google Scholar 

  15. Hanauer SB. Inflammatory bowel disease. N Engl J Med. 1996;334(13):841–8.

    Article  CAS  Google Scholar 

  16. Jones JH, Chapman M. Definition of megacolon in colitis. Gut. 1969;10(7):562–4.

    Article  CAS  Google Scholar 

  17. Present DH. Toxic megacolon. Med Clin North Am. 1993;77(5):1129–48.

    Article  CAS  Google Scholar 

  18. Sheth SG, Thomas LaMont J. Toxic megacolon. Lancet. 1998;351(9101):509–13.

    Article  CAS  Google Scholar 

  19. Heppell J, Farkouh E, Dubé S, Péloquin A, Morgan S, Bernard D. Toxic megacolon. An analysis of 70 cases. Dis Colon Rectum. 1986;29(12):789–92.

    Article  CAS  Google Scholar 

  20. Lewis JD. The utility of biomarkers in the diagnosis and therapy of inflammatory bowel disease. Gastroenterology. 2011;140(6):1817–1826.e2.

    Article  CAS  Google Scholar 

  21. Martin S, Vogel J. Restorative procedures in colonic Crohn disease. Clin Colon Rectal Surg. 2013;26(02):100–5.

    Article  Google Scholar 

  22. Hurst RD, Molinari M, Chung TP, Rubin M, Michelassi F. Prospective study of the features, indications, and surgical treatment in 513 consecutive patients affected by Crohn’s disease. Surgery. 1997;122(4):661–7; discussion 667–668.

    Article  CAS  Google Scholar 

  23. Schlussel AT, Steele SR, Alavi K. Current challenges in the surgical management of Crohn’s disease: a systematic review. Am J Surg. 2016;212(2):345–51.

    Article  Google Scholar 

  24. Ambe R, Campbell L, Cagir B. A comprehensive review of strictureplasty techniques in Crohn’s disease: types, indications, comparisons, and safety. J Gastrointest Surg. 2012;16(1):209–17.

    Article  Google Scholar 

  25. Lichtenstein GR, Hanauer SB, Sandborn WJ, Practice Parameters Committee of American College of Gastroenterology. Management of Crohn’s disease in adults. Am J Gastroenterol. 2009;104(2):465–83; quiz 464, 484.

    Article  Google Scholar 

  26. Ajlouni Y, Iser JH, Gibson PR. Endoscopic balloon dilatation of intestinal strictures in Crohn’s disease: safe alternative to surgery. J Gastroenterol Hepatol. 2007;22(4):486–90.

    Article  Google Scholar 

  27. Fornaro R, Caratto E, Caratto M, et al. Post-operative recurrence in Crohn’s disease. Critical analysis of potential risk factors. An update. Surgeon. 2015;13(6):330–47.

    Article  Google Scholar 

  28. Fazio VW, Marchetti F, Church M, et al. Effect of resection margins on the recurrence of Crohn’s disease in the small bowel. A randomized controlled trial. Ann Surg. 1996;224(4):563–71; discussion 571–573.

    Article  CAS  Google Scholar 

  29. Chandra R, Moore JWE. The surgical options and management of intestinal Crohn’s disease. Indian J Surg. 2011;73(6):432–8.

    Article  Google Scholar 

  30. Drenick EJ, Ament ME, Finegold SM, Corrodi P, Passaro E. Bypass enteropathy. Intestinal and systemic manifestations following small-bowel bypass. JAMA. 1976;236(3):269–72.

    Article  CAS  Google Scholar 

  31. Hawker PC, Gyde SN, Thompson H, Allan RN. Adenocarcinoma of the small intestine complicating Crohn’s disease. Gut. 1982;23(3):188–93.

    Article  CAS  Google Scholar 

  32. Yamamoto T, Fazio VW, Tekkis PP. Safety and efficacy of strictureplasty for Crohn’s disease: a systematic review and meta-analysis. Dis Colon Rectum. 2007;50(11):1968–86.

    Article  Google Scholar 

  33. Kim JW, Lee H-S, Ye BD, et al. Incidence of and risk factors for free bowel perforation in patients with Crohn’s disease. Dig Dis Sci. 2017;62(6):1607–14.

    Article  Google Scholar 

  34. Greenstein AJ, Mann D, Sachar DB, Aufses AH Jr. Free perforation in Crohn’s disease: I. A survey of 99 cases. Am J Gastroenterol. 1985;80(9):682–9.

    CAS  PubMed  Google Scholar 

  35. Greenstein AJ, Aufses AH Jr. Differences in pathogenesis, incidence and outcome of perforation in inflammatory bowel disease. Surg Gynecol Obstet. 1985;160(1):63–9.

    CAS  PubMed  Google Scholar 

  36. Graham E, Rao K, Cinti S. Medical versus interventional treatment of intra-abdominal abscess in patients with Crohn disease. Infect Dis: Res Treat. 2017;10:117991611770173.

    Google Scholar 

  37. Feagins LA, Holubar SD, Kane SV, Spechler SJ. Current strategies in the management of intra-abdominal abscesses in Crohn’s disease. Clin Gastroenterol Hepatol. 2011;9(10):842–50.

    Article  Google Scholar 

  38. Clancy C, Boland T, Deasy J, McNamara D, Burke JP. A meta-analysis of percutaneous drainage versus surgery as the initial treatment of Crohn’s disease-related intra-abdominal abscess. J Crohns Colitis. 2016;10(2):202–8.

    Article  Google Scholar 

  39. Golfieri R, Cappelli A, Giampalma E, et al. CT-guided percutaneous pelvic abscess drainage in Crohn’s disease. Tech Coloproctol. 2006;10(2):99–105.

    Article  CAS  Google Scholar 

  40. Gutierrez A, Lee H, Sands BE. Outcome of surgical versus percutaneous drainage of abdominal and pelvic abscesses in Crohn’s disease. Am J Gastroenterol. 2006;101(10):2283–9.

    Article  Google Scholar 

  41. Michelassi F, Balestracci T, Chappell R, Block GE. Primary and recurrent Crohn’s disease. Experience with 1379 patients. Ann Surg. 1991;214(3):230–8; discussion 238–240.

    Article  CAS  Google Scholar 

  42. Leowardi C, Heuschen G, Kienle P, Heuschen U, Schmidt J. Surgical treatment of severe inflammatory bowel diseases. Dig Dis. 2003;21(1):54–62.

    Article  Google Scholar 

  43. Hoffmann M, Siebrasse D, Schlöricke E, Bouchard R, Keck T, Benecke C. Long-term outcome of laparoscopic and open surgery in patients with Crohn’s disease. Open Access Surg. 2017;10:45–54.

    Article  Google Scholar 

  44. Rosman AS, Melis M, Fichera A. Metaanalysis of trials comparing laparoscopic and open surgery for Crohn’s disease. Surg Endosc. 2005;19(12):1549–55.

    Article  CAS  Google Scholar 

  45. Kessler H, Mudter J, Hohenberger W. Recent results of laparoscopic surgery in inflammatory bowel disease. World J Gastroenterol. 2011;17(9):1116–25.

    Article  Google Scholar 

  46. Aarons CB. Laparoscopic surgery for crohn disease: a brief review of the literature. Clin Colon Rectal Surg. 2013;26(2):122–7.

    Article  Google Scholar 

  47. Chung TP, Fleshman JW, Birnbaum EH, et al. Laparoscopic vs. open total abdominal colectomy for severe colitis: impact on recovery and subsequent completion restorative proctectomy. Dis Colon Rectum. 2009;52(1):4–10.

    Article  Google Scholar 

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Correspondence to Suzanne Gillern .

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Bogenberger, K., Conrad, R., Gillern, S. (2020). Acute Complications of Inflammatory Bowel Disease. In: Renton, D., Lim, R., Gallo, A., Sinha, P. (eds) The SAGES Manual of Acute Care Surgery. Springer, Cham. https://doi.org/10.1007/978-3-030-21959-8_12

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  • DOI: https://doi.org/10.1007/978-3-030-21959-8_12

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