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Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS) Method to Quantify Gabapentin and Pregabalin in Urine

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LC-MS in Drug Analysis

Part of the book series: Methods in Molecular Biology ((MIMB,volume 1872))

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Abstract

Gabapentin and pregabalin are anticonvulsant drugs that are also utilized for pain management. A mass spectrometry method was developed and validated to quantify gabapentin and pregabalin in urine to support testing for adherence.

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Acknowledgments

The authors would like to thank the ARUP Institute for Clinical and Experimental Pathology for support.

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Correspondence to Kamisha L. Johnson-Davis .

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Merrigan, S., Johnson-Davis, K.L. (2019). Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS) Method to Quantify Gabapentin and Pregabalin in Urine. In: Langman, L., Snozek, C. (eds) LC-MS in Drug Analysis. Methods in Molecular Biology, vol 1872. Humana Press, New York, NY. https://doi.org/10.1007/978-1-4939-8823-5_12

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  • DOI: https://doi.org/10.1007/978-1-4939-8823-5_12

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  • Publisher Name: Humana Press, New York, NY

  • Print ISBN: 978-1-4939-8822-8

  • Online ISBN: 978-1-4939-8823-5

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