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RNAi and MicroRNA-Mediated Gene Regulation in Stem Cells

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RNAi and Small Regulatory RNAs in Stem Cells

Part of the book series: Methods in Molecular Biology ((MIMB,volume 1622))

Abstract

Recently, RNAi and microRNAs (miRNAs) have become important tools to investigate the regulatory mechanism of stem cell maintenance and differentiation. In this short review, we give a brief overview of the discovery history, functions, and mechanisms of RNAi and miRNAs. We also discuss the RNAi as a tool to study the stem cell function and the potential future practical applications.

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  1. Department of Physiology, East Carolina University School of Medicine, 6N-98, 600 Moye Blvd, Greenville, NC, 27834, USA

    Alexander K. Murashov M.D., Ph.D.

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  1. Alexander K. Murashov M.D., Ph.D.
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Correspondence to Alexander K. Murashov M.D., Ph.D. .

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  1. Department of Biology, East Carolina University, Greenville, North Carolina, USA

    Baohong Zhang

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Murashov, A.K. (2017). RNAi and MicroRNA-Mediated Gene Regulation in Stem Cells. In: Zhang, B. (eds) RNAi and Small Regulatory RNAs in Stem Cells. Methods in Molecular Biology, vol 1622. Humana Press, New York, NY. https://doi.org/10.1007/978-1-4939-7108-4_2

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  • DOI: https://doi.org/10.1007/978-1-4939-7108-4_2

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