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Introduction to Macroporous Cryogels

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Affinity Chromatography

Part of the book series: Methods in Molecular Biology ((MIMB,volume 1286))

Abstract

Cryogels are highly elastic three-dimensional materials consisting of a network of interconnected macropores. This unique morphology combined with high mechanical and chemical stability provides excellent mass flow properties. The matrices are synthesized at subzero temperatures from almost any gel-forming precursor. The main fields of application are in biotechnology as 3D-scaffold for cell cultivation, and tissue engineering, or bioseparation as chromatographic media for the separation and purification of biomolecules. This chapter briefly highlights the preparation, properties, and application of these materials.

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Authors and Affiliations

  1. Leibniz-Institut für Oberflächenmodifizierung, Permoserstraße 15, Leipzig, 04318, Germany

    Senta Reichelt

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  1. Senta Reichelt
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Correspondence to Senta Reichelt .

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  1. Leibniz-Institut für Oberflächenmodifizierung, Leipzig, Germany

    Senta Reichelt

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Reichelt, S. (2015). Introduction to Macroporous Cryogels. In: Reichelt, S. (eds) Affinity Chromatography. Methods in Molecular Biology, vol 1286. Humana Press, New York, NY. https://doi.org/10.1007/978-1-4939-2447-9_14

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  • DOI: https://doi.org/10.1007/978-1-4939-2447-9_14

  • Publisher Name: Humana Press, New York, NY

  • Print ISBN: 978-1-4939-2446-2

  • Online ISBN: 978-1-4939-2447-9

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