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Overview of Angiogenesis Inhibitors from Natural Sources

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Biochemical Basis and Therapeutic Implications of Angiogenesis

Part of the book series: Advances in Biochemistry in Health and Disease ((ABHD,volume 6))

Abstract

Angiogenesis, the biological process of formation of new blood vessels from pre-existing ones, is essential for many diseases and its modulation is considered to be an important therapeutic strategy. It is controlled by various pro and anti-­angiogenic factors. Plants, animals, microbes, and marine are the natural sources of various chemical constituents possessing anti-angiogenic activity which may act as leads in future angiogenesis inhibitors therapy. This review highlights the anti-­angiogenic activity of many constituents from natural sources along with their biochemical mechanisms.

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Acknowledgments

We express our gratitude to Department of Biotechnology (DBT), Govt. of India for providing financial support and SPP School of Pharmacy & Technology Management, Mumbai, India for providing facilities to carry out the research work.

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Authors and Affiliations

  1. Department of Pharmaceutical Chemistry, SPP School of Pharmacy & Technology Management, SVKM’s NMIMS, V. L. Mehta Road, Mumbai, Maharashtra, India

    Dipti Gatne

  2. Department of Pharmacology, SPP School of Pharmacy & Technology Management, SVKM’s NMIMS, V. L. Mehta Road, Mumbai, 400056, Maharashtra, India

    Veeranjaneyulu Addepalli

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  1. Dipti Gatne
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  2. Veeranjaneyulu Addepalli
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Correspondence to Veeranjaneyulu Addepalli .

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Editors and Affiliations

  1. Div. of Cardiovascular Medicine, UAMS, Little Rock, AR, USA, 4301 W Markham, Little Rock, 72205, Arkansas, USA

    Jawahar L. Mehta

  2. Institute of Cardiovascular Sciences, St. Boniface Hosp. Research, Univ. of Ma, 351 Tache Avenue, Winnipeg, R2H 2A6, Manitoba, Canada

    Naranjan S. Dhalla

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Gatne, D., Addepalli, V. (2013). Overview of Angiogenesis Inhibitors from Natural Sources. In: Mehta, J., Dhalla, N. (eds) Biochemical Basis and Therapeutic Implications of Angiogenesis. Advances in Biochemistry in Health and Disease, vol 6. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-5857-9_26

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