Abstract
Discoid lupus erythematosus (DLE) is a chronic, scarring, photosensitive skin inflammation representing the benign type of the lupus erythematosus spectrum. Potent topical steroids and antimalarials are the mainstay of treatment. Case reports and case series of cryotherapy in DLE lesions document improving of itching, erythema, scaling, scarring and pain with a minor chance of relapse. Pain in the thaw period, hypo-pigmented mild scaring, loss of eyelashes, and persistent telangiectasias are reported side effects. In cases of DLE lesions that are resistant to local or systemic therapies, cryotherapy should be considered as alternative local treatment modality in DLE.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Kuhn A, Sontheimer RD, Ruzicka T. Clinical manifestation of cutaneous lupus erythematosus. In: Kuhn A, Lehmann P, Ruzicka T, editors. Cutaneous lupus erythematosus. Berlin: Springer; 2005. p. 59–93.
Fabbri P, Cardinali C, Giomi B, Caproni M. Cutaneous lupus erythematosus: diagnosis and management. Am J Clin Dermatol. 2003;4(7):449–65.
Jessop S, Whitelaw DA, Delamere FM. Drugs for discoid lupus erythematosus. Cochrane Database Syst Rev. 2009;7(4):CD002954.
Panjwani S. Early diagnosis and treatment of discoid lupus erythematosus. J Am Board Fam Med. 2009;22(2):206–13.
Cortés-Hernández J, Torres-Salido M, Castro-Marrero J, Vilardell-Tarres M. Thalidomide in the treatment of refractory cutaneous lupus erythematosus: prognostic factors of clinical outcome. Br J Dermatol. 2012;166(3):616–23.
Goldstein E, Carey W. Discoid lupus erythematosus : successful treatment with oral methotrexate. Arch Dermatol. 1994;130(7):938–9.
Goyal S, Nousari HC. Treatment of resistant discoid lupus erythematosus of the palms and soles with mycophenolate mofetil. J Am Acad Dermatol. 2001;45(1):142–4.
Booken N, Schumann T, Fuchslocher M, Goerdt S, Goebeler M. Successful therapy of discoid lupus erythematosus with efalizumab. Hautarzt. 2010;61(3):246–9.
Ekbäck MP, Troilius A. Laser therapy for refractory discoid lupus erythematosus when everything else has failed. J Cosmet Laser Ther. 2013;15(5):260–5.
Molin L, Tarstedt M. Discoid lupus erythematosus treated with cryotherapy. J Dermatolog Treat. 2003;14(3):182–3.
Wollina U, Prifert K. Cryogenic contact therapy of cutaneous lesions of lupus erythematosus. Dermatol Monatsschr. 1990;176(2–3):105–9.
Koch M, Horwath-Winter J, Aberer E, Salmhofer W, Klein A. Cryotherapy in discoid lupus erythematosus (DLE). Ophthalmologe. 2008;105(4):381–3.
Fernández-Guarino M, Pérez-GarcÃa B, Harto A, Jaén P. Discoid lupus erythematosus: good response to treatment with photodynamic therapy. J Eur Acad Dermatol Venereol. 2008;22(9):1142–3.
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2016 Springer-Verlag London
About this chapter
Cite this chapter
Brandner, M., Klein-Theyer, A. (2016). Lupus, Discoid. In: Abramovits, W., Graham, G., Har-Shai, Y., Strumia, R. (eds) Dermatological Cryosurgery and Cryotherapy. Springer, London. https://doi.org/10.1007/978-1-4471-6765-5_94
Download citation
DOI: https://doi.org/10.1007/978-1-4471-6765-5_94
Published:
Publisher Name: Springer, London
Print ISBN: 978-1-4471-6764-8
Online ISBN: 978-1-4471-6765-5
eBook Packages: MedicineMedicine (R0)