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Preoperative Chemo Versus Chemoradiotherapy for Regionally Advanced Esophageal Adenocarcinoma

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Difficult Decisions in Thoracic Surgery

Part of the book series: Difficult Decisions in Surgery: An Evidence-Based Approach ((DDSURGERY,volume 1))

Abstract

The role of neoadjuvant therapy in patients with resectable locally advanced esophageal cancer has been the focus of multiple trials in the past two decades. This is due to the poor results of surgery alone in this patient population, as well as the disappointing results of trials addressing postoperative adjuvant therapy. The optimal regime, be it preoperative chemotherapy or chemoradiation, has been the subject of debate amongst physicians involved in the care of patients with esophageal cancer. The published data concerning options for neoadjuvant therapy is discussed in detail.

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Authors and Affiliations

  1. Division of Thoracic Surgery, CHUM Endoscopic Tracheobronchial and Oesophageal Center (C.E.T.O.C.), University of Montreal, 1560 Sherbrooke Street East, 8e CD – Pavillon Lachapelle, D-8051, Montreal, QC, H2L 4 M1, Canada

    Basil S. Nasir MBBCh & Moishe Liberman MD, PhD

Authors
  1. Basil S. Nasir MBBCh
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  2. Moishe Liberman MD, PhD
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Correspondence to Moishe Liberman MD, PhD .

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Editors and Affiliations

  1. Surgery, University of Chicago, Chicago, Illinois, USA

    Mark K. Ferguson

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© 2014 Springer-Verlag London

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Nasir, B.S., Liberman, M. (2014). Preoperative Chemo Versus Chemoradiotherapy for Regionally Advanced Esophageal Adenocarcinoma. In: Ferguson, M. (eds) Difficult Decisions in Thoracic Surgery. Difficult Decisions in Surgery: An Evidence-Based Approach, vol 1. Springer, London. https://doi.org/10.1007/978-1-4471-6404-3_23

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  • DOI: https://doi.org/10.1007/978-1-4471-6404-3_23

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  • Publisher Name: Springer, London

  • Print ISBN: 978-1-4471-6403-6

  • Online ISBN: 978-1-4471-6404-3

  • eBook Packages: MedicineMedicine (R0)

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